| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2009: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2008: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Research Abstract |
The circadian clock can be reconstituted in vitro by the KaiA, KaiB, and KaiC proteins in the presence of ATP. In this study, LdpA presumed to be a redox sensor in cyanobacteria was analyzed biochemically. The structure of the molecule was changed by a redox state. Moreover, it was found that pH of the KaiABC reconstitution system have an effect on the length of the cycle. The two factors, pH in the cell and LdpA, could get involved in the change of the period length the cycle by light.
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