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Molecular phylogeny of species of Rattus and Mus and its use for biodiversity studies

Research Project

Project/Area Number 20570078
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Biodiversity/Systematics
Research InstitutionHokkaido University

Principal Investigator

SUZUKI Hitoshi  Hokkaido University, 大学院・地球環境科学研究院, 准教授 (40179239)

Project Period (FY) 2008 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2009: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2008: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywordsハツカネズミ / クマネズミ / 遺伝子 / 毛色 / 分子系統 / 適応進化 / ハプロタイプ構造解析 / Mc1r / 人為的移入 / 毛色多型 / モデル生物 / 遺伝的多様性 / 遺伝子進化 / 自然選択 / 適応放散
Research Abstract

Two lineages of Mus from Myanmar were shown to be valid species from our molecular phylogenetic study. The ancestral lineage of the subgenus Mus was shown to have an accelerated rate of dN/dS in the coat color related gene Mc1r, implying the presence of adaptive evolution associated with coat color. The black rat Rattus rattus with agouti and melanistic forms in dorsal coat color possessed a responsible SNP, G280A, in Mc1r. Our newly developed system, haplotype structure analysis, is proven to be effective to reveal introgressive hybridization events at both historical and contemporary ages.

Report

(4 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (54 results)

All 2011 2010 2009 2008 Other

All Journal Article (24 results) (of which Peer Reviewed: 20 results) Presentation (28 results) Book (2 results)

  • [Journal Article] Origin of agouti-melanistic polymorphism in wild Black Rats (Rattus rattus) inferred from Mclr gene sequences.2011

    • Author(s)
      Yoshikazu Kambe
    • Journal Title

      Zoological Science

      Volume: (in press)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Detection of recombinant haplotypes in wild mice (Mus musculus) provides new insights into the origin of Japanese mice.2010

    • Author(s)
      Nunome, M., Ishimori, C., Aplin, K., Tsuchiya, K., Yonekawa, H., Moriwaki, K., Suzuki H.
    • Journal Title

      Molecular Ecology 19

      Pages: 2474-2489

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] The influence of Pleistocene refugia on the evolutionary history of the Japanese hare, Lepus brachyurus.2010

    • Author(s)
      Nunome, M., Torii, H., Matsuki, R., Kinoshita, G., Suzuki H.
    • Journal Title

      Zoological Science 27

      Pages: 746-754

    • NAID

      40017358638

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Mitochondrial phylogeography and population history of the large Japanese wood mouse (Apodemus speciosus) on Sado Island.2010

    • Author(s)
      Tomozawa, M., Tomida, H., Suzuki H., Tsuchiya, K.
    • Journal Title

      Japan. Mammal Study 25

      Pages: 273-285

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Mus lepidoides (Muridae, Rodentia) of Central Burma is a Distinct Species of Potentially Great Evolutionary and Biogeographic Significance.2010

    • Author(s)
      Shimada, T., Aplin, K. P., Suzuki H.
    • Journal Title

      Zoological Science 27

      Pages: 449-459

    • NAID

      40017358602

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] The influence of Pleistocene refugia on the evolutionary history of the Japanese hare, Lepus brachyurus2010

    • Author(s)
      Nunome Mitsuo
    • Journal Title

      Zoological Science

      Volume: 27 Pages: 746-754

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Mus lepidoides(Muridae, Rodentia)of Central Burma is a Distinct Species of Potentially Great Evolutionary and Biogeographic Significance.2010

    • Author(s)
      Shimada Tomofumi
    • Journal Title

      Zoological Science (in press)

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Detection of recombinant haplotypes in wild mice(Mus musculus)provides new insights into the origin of Japanese mice.2010

    • Author(s)
      Nunome Mitsuo
    • Journal Title

      Molecular Ecology (in press)

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Deciphering and dating the red panda's ancestry and early adaptive radiation of Musteloidea.2009

    • Author(s)
      Sato, J.J., Wolsan, M., Minami, S., Hosoda, T., Sinaga, H.H., Hiyama, K., Yamaguchi, Y., Suzuki H.
    • Journal Title

      Molecular Phylogenetics and Evolution 53

      Pages: 907-922

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Comparative analysis of evolutionary modes in Mc1r coat color gene in wild mice and mustelids.2009

    • Author(s)
      Shimada, T, Sato, JJ, Aplin, KP, Suzuki H.
    • Journal Title

      Genes & Genetic Systems 84

      Pages: 225-231

    • NAID

      10026091041

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] A molecular phylogenetic view of mammals in the "three-story museum" of Hokkaido, Honshu, and Ryukyu Islands.2009

    • Author(s)
      鈴木仁
    • Journal Title

      The Wild Mammals of Japan.(Eds., Ohdachi SD, Ishibashi Y, Iwasa MA, Saitoh T. Shoukadoh, Kyoto.)

      Pages: 261-263

    • Related Report
      2010 Final Research Report
  • [Journal Article] Mozaic genome structure of multiple subspecies in the Japanese wild mouse Mus musculus.2009

    • Author(s)
      Nunome., M., Suzuki H., Moriwaki K.
    • Journal Title

      The Wild Mammals of Japan.(Eds., Ohdachi SD, Ishibashi Y, Iwasa MA, Saitoh T Shoukadoh, Kyoto.)

      Pages: 180-181

    • Related Report
      2010 Final Research Report
  • [Journal Article] オキナワトゲネズミ再発見とトゲネズミ研究の最近2009

    • Author(s)
      山田文雄、黒岩麻里、鈴木仁、村田智慧
    • Journal Title

      哺乳類科学 49

      Pages: 133-135

    • NAID

      10030471878

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Comparative analysis of evolutionary modes in Mc1r coat color gene in wild mice and mustelids.2009

    • Author(s)
      Tomofumi Shimada
    • Journal Title

      Genes & Genetic Systems 84

      Pages: 225-231

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article]2009

    • Author(s)
      Nunome Mitsuo
    • Journal Title

      The Wild Mammals of Japan(Shoukadoh, Kyoto)

      Pages: 180-181

    • Related Report
      2009 Annual Research Report
  • [Journal Article] A biogeographic view of Apodemus in Asia and Europe inferred from nuclear and mitochondrial gene sequences.2008

    • Author(s)
      Suzuki H., Filippucci, MG., Chelomina, GN., Sato, JJ., Serizawa, K. Nevo, E.
    • Journal Title

      Biochemical Genetics 46

      Pages: 329-346

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] A trend of central versus peripheral structuring in mitochondrial and nuclear gene sequences of the Japanese wood mouse, Apodemus speciosus.2008

    • Author(s)
      Tomozawa, M., Suzuki H.
    • Journal Title

      Zoological Science 25

      Pages: 273-285

    • NAID

      40016029301

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Phylogenetic relationships of the short-faced mole, Scaptochirus moschatus (Mammalia : Eulipotyphla), among Eurasian fossorial moles, as inferred from mitochondrial and nuclear gene sequences.2008

    • Author(s)
      Shinohara,A., Kawada, S., Harada, M., Koyasu, K., Oda, S., Suzuki H.
    • Journal Title

      Mammal Study 33

      Pages: 77-82

    • NAID

      10027006818

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Isolation and development of microsatellite markers for the Japanese dormouse, Glirulus japonicus.2008

    • Author(s)
      Yasuda, SP., Nakayama, A., Iwabuchi, M., Minato, S., Tsuchiya, K., Suzuki H.
    • Journal Title

      Molecular Ecology Resources 9

      Pages: 569-571

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] 日本の野生哺乳類にみる毛色の進化2008

    • Author(s)
      鈴木仁
    • Journal Title

      生物の科学遺伝 62

      Pages: 60-61

    • Related Report
      2010 Final Research Report
  • [Journal Article] A biogeographic view of Apodemus in Asia and Europe inferred from nucl ear and mitochondrial eene seauences2008

    • Author(s)
      Hitoshi Suzuki
    • Journal Title

      Biochemical Genetics 46

      Pages: 329-334

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A Trend of Central versus Peripheral Structuring Appeared in Mitochondrial a nd Nuclear Gene Sequences of the Japanese Wood Mouse Apodemus speciosus2008

    • Author(s)
      Morihiko Tomozawa
    • Journal Title

      Zoologicl Science 25

      Pages: 273-285

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Phylogenetic relationships of the short-faced mole, Scaptochirus mo schatus (Mammalia : Eulipotyphla), among Eurasian fossorial moles, as inferred from mitochondrial and nuclear gene sequences2008

    • Author(s)
      Akio Shinohara
    • Journal Title

      Mammal Study 33

      Pages: 77-82

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Origin of agouti-melanistic polymorphism in wild Black Rats (Rattus rattus) inferred from Mc1r gene sequences.

    • Author(s)
      Kambe, Y., Tanikawa, T., Matsumoto, Y, Tomozawa, M., Aplin, K.P, Suzuki H.
    • Journal Title

      Zoological Science in press

    • NAID

      40018937059

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Presentation] 野生哺乳類にみる毛色の進化2010

    • Author(s)
      鈴木仁
    • Organizer
      日本動物学会
    • Place of Presentation
      東京都・東京大学
    • Year and Date
      2010-09-24
    • Related Report
      2010 Annual Research Report
  • [Presentation] マウス亜種とその地理的展開2010

    • Author(s)
      鈴木仁
    • Organizer
      国立遺伝学研究所・研究集会「マウスを中心としたForward geneticsの新展開」
    • Place of Presentation
      三島
    • Year and Date
      2010-04-23
    • Related Report
      2010 Final Research Report
  • [Presentation] 野生哺乳類にみる毛色の進化2010

    • Author(s)
      鈴木仁、友澤森彦、布目三夫、佐藤淳
    • Organizer
      第81回日本動物学会
    • Place of Presentation
      東京
    • Related Report
      2010 Final Research Report
  • [Presentation] クマネズミのMclr遺伝子の変異と毛色多型の解析2010

    • Author(s)
      神戸嘉一、谷川力・松本泰治・友澤森彦・Ken P.Aplin・鈴木仁
    • Organizer
      第82回日本遺伝学会
    • Place of Presentation
      札幌
    • Related Report
      2010 Final Research Report
  • [Presentation] ハツカネズミの毛色関連遺伝子Mclr周辺領域の塩基多様度の減少2010

    • Author(s)
      児玉紗也香、布目三夫、森脇和郎、鈴木仁
    • Organizer
      第82回日本遺伝学会
    • Place of Presentation
      札幌
    • Related Report
      2010 Final Research Report
  • [Presentation] 複数遺伝子座を用いたニホンノウサギ4亜種の遺伝的背景の解析2009

    • Author(s)
      布目三夫, 鳥居春己, 松木吏弓, 木下豪太, 鈴木仁
    • Organizer
      日本哺乳類学会2009年度大会
    • Place of Presentation
      台湾台北
    • Year and Date
      2009-11-24
    • Related Report
      2010 Final Research Report
  • [Presentation] ミトコンドリアDNAから見た台湾産イタチ類相の形成史2009

    • Author(s)
      細田徹治・林良恭・鈴木仁・岩佐真宏・原田正史・佐藤淳・土屋公幸
    • Organizer
      日本哺乳類学会
    • Place of Presentation
      台湾台北
    • Year and Date
      2009-11-24
    • Related Report
      2010 Final Research Report
  • [Presentation] ユーラシア産野生ハツカネズミの系統地理学的解析2009

    • Author(s)
      臼田大輝、高田豊行、森脇和郎、吉川欣亮、城石俊彦、鈴木仁
    • Organizer
      日本遺伝学会第81回大会
    • Place of Presentation
      松本
    • Year and Date
      2009-09-17
    • Related Report
      2010 Final Research Report
  • [Presentation] 日本産小型哺乳類の系統地理学的概観と進化遺伝学への活用2009

    • Author(s)
      鈴木仁
    • Organizer
      日本遺伝学会 ワークショップ:遺伝学の素材としての日本の野生生物
    • Place of Presentation
      松本(オーガナイザー)
    • Year and Date
      2009-09-16
    • Related Report
      2010 Final Research Report
  • [Presentation] 日本産小型哺乳類の系統地理学的概観と進化遺伝学への活用2009

    • Author(s)
      鈴木仁
    • Organizer
      日本遺伝学会
    • Place of Presentation
      長野県・信州大学
    • Year and Date
      2009-09-16
    • Related Report
      2009 Annual Research Report
  • [Presentation] 野生ネズミ類の多様陛の歴史とゲノム学への活用2009

    • Author(s)
      鈴木仁
    • Organizer
      第89回理研バイオリソースセンターセミナー
    • Place of Presentation
      つくば(招待講演)
    • Year and Date
      2009-08-04
    • Related Report
      2010 Final Research Report
  • [Presentation] Mus属のユーラシア亜熱帯域での展開とモロシヌスの来た道2009

    • Author(s)
      鈴木仁
    • Organizer
      第23回モロシヌス研究会
    • Place of Presentation
      大津市
    • Year and Date
      2009-07-11
    • Related Report
      2010 Final Research Report
  • [Presentation] 哺乳類の多様陛研究2009

    • Author(s)
      桐原崇・鈴木仁
    • Organizer
      (北海道大学・地球環境科学研究院)日本産モグラ類の分子系統と系統地理研究交流会
    • Place of Presentation
      札幌
    • Year and Date
      2009-06-23
    • Related Report
      2010 Final Research Report
  • [Presentation] A role of Pleistocene refugia in shaping genetic diversity of the Japanese hare, Lepus brach yurus2009

    • Author(s)
      Mitsuo Nunome, Harumi Torii, Rikyu Matsuki, Fumio Yamada, Kimiyuki Tsuchiya, Hitoshi Suzuki
    • Organizer
      第10回国際哺乳類学会議(10th International Mammalogical Congress
    • Place of Presentation
      アノレビンチン
    • Related Report
      2010 Final Research Report
  • [Presentation] 食肉類における毛色関連遺伝子Mclrの進化的動態2009

    • Author(s)
      幡中迫彦、友澤森彦、佐藤淳、細田徹治、鈴木仁
    • Organizer
      第11回日本進化学会大会
    • Place of Presentation
      札幌
    • Related Report
      2010 Final Research Report
  • [Presentation] トゲネズミの進化的位置づけ2008

    • Author(s)
      鈴木仁
    • Organizer
      日本哺乳類学会
    • Place of Presentation
      山口
    • Year and Date
      2008-09-13
    • Related Report
      2010 Final Research Report
  • [Presentation] ミトコンドリアDNAおよび核遺伝子配列からみたコウベモグラMogera wogura2008

    • Author(s)
      桐原崇・篠原明男・土屋公幸・原田正史・Kryukov Alexei P.・鈴木仁
    • Organizer
      日本哺乳類学会
    • Place of Presentation
      山口
    • Year and Date
      2008-09-13
    • Related Report
      2010 Final Research Report
  • [Presentation] 複数の遺伝子配列の変異に基づく日本産野生ハツカネズミの起源2008

    • Author(s)
      鈴木仁, 臼田大輝, 布目三夫, 森脇和郎
    • Organizer
      日本動物学会第79回大会
    • Place of Presentation
      福岡
    • Year and Date
      2008-09-06
    • Related Report
      2010 Final Research Report
  • [Presentation] 複数の遺伝子配列の変異に基づく日本産野生ハツカネズミの起源2008

    • Author(s)
      鈴木仁
    • Organizer
      日本動物学会第79回大会
    • Place of Presentation
      福岡大学(福岡)
    • Year and Date
      2008-09-06
    • Related Report
      2008 Annual Research Report
  • [Presentation] 日本産野生ハツカネズミのが持つことなる亜種に由来する4つの遺伝的要素の特定2008

    • Author(s)
      鈴木仁, 臼田大輝, 布目三夫, 土屋公幸, 米川博通, 森脇和郎
    • Organizer
      日本遺伝学会第80回大会
    • Place of Presentation
      名古屋
    • Year and Date
      2008-09-03
    • Related Report
      2010 Final Research Report
  • [Presentation] ESU策定のための汎用分子マーカー開発の試み-ニホンヤマネをモデルとして-2008

    • Author(s)
      安田俊平・岩渕真奈美・湊秋作・土屋公幸・鈴木仁
    • Organizer
      日本進化学会第10回大会
    • Place of Presentation
      東京
    • Year and Date
      2008-08-22
    • Related Report
      2010 Final Research Report
  • [Presentation] 第三紀後期以降の哺乳類の断続的放散と日本産小型哺乳類の起源~韓国から日本への系統移入の多様な物語~2008

    • Author(s)
      鈴木仁
    • Organizer
      韓国国立バイオリソースセンター(National Institute of Biological Resources (NIBR))
    • Place of Presentation
      韓国仁川
    • Year and Date
      2008-05-21
    • Related Report
      2010 Final Research Report
  • [Presentation] マイクロサテライトを用いたニホンヤマネの配偶システムと巣箱共有個体の血縁関係解析2008

    • Author(s)
      安田俊平・岩渕真奈美・中山文・湊秋作・鈴木仁
    • Organizer
      日本哺乳類学会
    • Place of Presentation
      山口
    • Related Report
      2010 Final Research Report
  • [Presentation] マイクロサテライトマーカーを用いたアカネズミ島唄集団の遺伝解析2008

    • Author(s)
      友澤森彦, 鈴木仁, 土屋公幸
    • Organizer
      日本哺乳類学会
    • Place of Presentation
      山口
    • Related Report
      2010 Final Research Report
  • [Presentation] 第四紀の複数のレフユージアがニホンノウサギの遺伝的多様性に与えた影響についての系統地理学的解析2008

    • Author(s)
      布目三夫, 鳥居春己, 山田文雄, 土屋公幸, 鈴木仁
    • Organizer
      日本哺乳類学会
    • Place of Presentation
      山口
    • Related Report
      2010 Final Research Report
  • [Presentation] 野生ハツカネズミの系統地理学的研究へのSNPsの活用2008

    • Author(s)
      臼田大輝、吉川欣亮、森脇和郎、鈴木仁
    • Organizer
      日本哺乳類学会
    • Place of Presentation
      山口
    • Related Report
      2010 Final Research Report
  • [Presentation] Mclr遺伝子の変異に基づく日本産クマネズミRattus rattusの遺伝的背景の解析2008

    • Author(s)
      神戸嘉一・谷川力・矢部辰男・前園泰徳・石田健・土屋公幸・鈴木荘介・松本泰治・Aplin Ken P.・鈴木仁
    • Organizer
      日本哺乳類学会
    • Place of Presentation
      山口
    • Related Report
      2010 Final Research Report
  • [Presentation] The role of Pleistocene refugia in shaping genetic diversity of the Japanese hare (Lepus brachyurus).2008

    • Author(s)
      布目三夫
    • Organizer
      Hokkaido University Sustainability Weeks G8 Sutninit Round
    • Place of Presentation
      札幌
    • Related Report
      2010 Final Research Report
  • [Book] カラスの自然史(第1章「カラス類の系統進化史」)(樋口広芳・黒沢令子編)2010

    • Author(s)
      Kyrukov A.P., Haring E., 鈴木仁
    • Publisher
      北海道大学出版会
    • Related Report
      2010 Final Research Report
  • [Book] ボルネオ(大崎満、岩熊敏男編)(第3章レッドエコシステム)2008

    • Author(s)
      甲山隆司、鈴木仁
    • Publisher
      岩波出版
    • Related Report
      2010 Final Research Report

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Published: 2008-04-01   Modified: 2016-04-21  

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