| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2009: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2008: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Research Abstract |
The development of brain is a multiple processes consisting of neurogenesis, axon guidance, and the formation of neural layers. Although the Drosophila brain is much simpler than the human brain, its development is under the control of a conserved genetic program that is in common with the development of the vertebrate brain. In this study, we have performed molecular genetic analysis of the development of higher order brain structures, focusing on the mushroom body and the antennal lobe, prominent neural structures in Drosophila. Our study has disclosed novel control mechanisms of axodendritic development that include homeodomain transcription factors and intracellular transport regulators.
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