The molecular mechanism of Golgi cisternal maturation
| Project/Area Number |
20580073
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Applied microbiology
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| Research Institution | The University of Tokyo |
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Principal Investigator |
NODA Yoichi The University of Tokyo, 農学生命科学研究科, 助教 (90282699)
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| Project Period (FY) |
2008 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2008: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | 微生物機能 / 出芽酵母 / 小胞輸送 / 糖転移酵素 |
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| Research Abstract |
We found that Svp26, a yeast ER-Golgi resident membrane protein, is involved in the Golgi localization of the N-mannosyltransferases Mnn2 and Mnn5, and the O-mannosyltransferases Ktr3, Kre2 and Ktr1. We also found the membrane proteins involved in the Golgi localization of Ktr4, whose Golgi localization is independent of Svp26. We found that mannosyltransferases display distinct detergent solubility.
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Report
(4 results)
Research Products
(27 results)
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[Journal Article] Inhibitory activity of blasticidin A, astrong aflatoxin production inhibitor, on protein synthesis of yeast : selective inhibition of aflatoxin production by protein synthesis inhibitors2010
Author(s)
Yoshinari, T., Noda, Y., Yoda, K., Sezaki, H., Nagasawa, H., Sakuda, S.
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Journal Title
Journal of Antibiotics (Tokyo)
Volume: 63
Pages: 309-314
Related Report
Peer Reviewed
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