Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2008: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
|
Research Abstract |
We found that Svp26, a yeast ER-Golgi resident membrane protein, is involved in the Golgi localization of the N-mannosyltransferases Mnn2 and Mnn5, and the O-mannosyltransferases Ktr3, Kre2 and Ktr1. We also found the membrane proteins involved in the Golgi localization of Ktr4, whose Golgi localization is independent of Svp26. We found that mannosyltransferases display distinct detergent solubility.
|