• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

The molecular mechanism of Golgi cisternal maturation

Research Project

Project/Area Number 20580073
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Applied microbiology
Research InstitutionThe University of Tokyo

Principal Investigator

NODA Yoichi  The University of Tokyo, 農学生命科学研究科, 助教 (90282699)

Project Period (FY) 2008 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2008: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywords微生物機能 / 出芽酵母 / 小胞輸送 / 糖転移酵素
Research Abstract

We found that Svp26, a yeast ER-Golgi resident membrane protein, is involved in the Golgi localization of the N-mannosyltransferases Mnn2 and Mnn5, and the O-mannosyltransferases Ktr3, Kre2 and Ktr1. We also found the membrane proteins involved in the Golgi localization of Ktr4, whose Golgi localization is independent of Svp26. We found that mannosyltransferases display distinct detergent solubility.

Report

(4 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (27 results)

All 2011 2010 2009 2008

All Journal Article (10 results) (of which Peer Reviewed: 8 results) Presentation (17 results)

  • [Journal Article] Kre6 Protein Essential for Yeast Cell Wall -1,6-GlucanSynthesis Accumulates at Sites of Polarized Growth2011

    • Author(s)
      Tomokazu Kurita, Yoichi Noda, Tomoko Takagi, Masako Osumi, Koji Yoda
    • Journal Title

      J.Biol.Chem. 286

      Pages: 7429-7438

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Kre6 Protein Essential for Yeast Cell Wall -1,6-GlucanSynthesis Accumulates at Sites of Polarized Growth2011

    • Author(s)
      Tomokazu Kurita, Yoichi Noda, Tomoko Takagi, Masako Osumi, Koji Yodi
    • Journal Title

      Journal of Biological Chemistry

      Volume: 286 Pages: 7429-7438

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Svp26 Facilitates Endoplasmic Reticulum-to-Golgi Transport of a Set of Mannosyltransferases in Saccharomyces cerevisiae2010

    • Author(s)
      Yoichi Noda, Koji Yoda
    • Journal Title

      J.Biol.Chem. 285

      Pages: 15420-15429

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Inhibitory activity of blasticidin A, a strong aflatoxin production inhibitor, on protein synthesis of yeast : selective inhibition of aflatoxin production by protein synthesis inhibitors.2010

    • Author(s)
      Yoshinari T, Noda Y, Yoda K, Sezaki H, Nagasawa H, Sakuda S
    • Journal Title

      J.Antibiot (Tokyo) 63

      Pages: 309-314

    • NAID

      10030708631

    • Related Report
      2010 Final Research Report
  • [Journal Article] Svp26 Facilitates Endoplasmic Reticulum-to-Golgi Transport of a Set of Mannosyltransferases in Saccharomyces cerevisiae2010

    • Author(s)
      Yoichi Noda, Koji Yoda
    • Journal Title

      Journal of Biological Chemistry

      Volume: 285 Pages: 15420-15429

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Inhibitory activity of blasticidin A, astrong aflatoxin production inhibitor, on protein synthesis of yeast : selective inhibition of aflatoxin production by protein synthesis inhibitors2010

    • Author(s)
      Yoshinari, T., Noda, Y., Yoda, K., Sezaki, H., Nagasawa, H., Sakuda, S.
    • Journal Title

      Journal of Antibiotics (Tokyo)

      Volume: 63 Pages: 309-314

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Kei1 : a Novel Subunit of Inositolphosphorylceramide Synthase, Essential for Its Enzyme Activity and Golgi Localization2009

    • Author(s)
      Keisuke Sato, Yoichi Noda, Koji Yoda
    • Journal Title

      Mol.Biol.Cell. 20

      Pages: 4444-4457

    • Related Report
      2010 Final Research Report
  • [Journal Article] Keil : A Novel Subunit of Inositolphosphorylceramide Synthase, Essential for Its Enzyme Activity and Golgi Localization2009

    • Author(s)
      Keisuke Sato, Yoichi Noda, Koji Yoda
    • Journal Title

      Molecular Biology of the Cell 20

      Pages: 4444-4457

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Ypt11 functions in bud-directed transport of the Golgi by l inking Myo2 to the coatomer subunit Ret22008

    • Author(s)
      Seisuke Arai, Yoichi Noda, Satoko Kainuma, Ikuo Wada, Koji Yoda
    • Journal Title

      Curr.Biol. 18

      Pages: 987-991

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Ypt11 functions in bud-directed transport of the Golgi by linking Myo2 to the coatomer subunit Ret22008

    • Author(s)
      Seisuke Arai, Yoichi Noda, Satoko Kainuma, lkuo Wada and Koji Yoda
    • Journal Title

      Current Biology 18

      Pages: 987-991

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Presentation] 出芽酵母Svp26 はゴルジ体マンノース転移酵素Ktr1の小胞体搬出アダプターとして機能する2011

    • Author(s)
      野田陽一,依田幸司
    • Organizer
      日本農芸化学会2011年度大会
    • Place of Presentation
      京都女子大学
    • Year and Date
      2011-03-27
    • Related Report
      2010 Final Research Report
  • [Presentation] Kre2ファミリーマンノース転移酵素Ktr4のゴルジ体局在機構2011

    • Author(s)
      石井美奈子,野田陽一,依田幸司
    • Organizer
      日本農芸化学会2011年度大会
    • Place of Presentation
      京都女子大学
    • Year and Date
      2011-03-27
    • Related Report
      2010 Annual Research Report 2010 Final Research Report
  • [Presentation] 出芽酵母Svp26はゴルジ体マンノース転移酵素Ktrlの小胞体搬出アダプターとして機能する2011

    • Author(s)
      野田陽一, 依田幸司
    • Organizer
      日本農芸化学会2011年度大会
    • Place of Presentation
      京都女子大学
    • Year and Date
      2011-03-27
    • Related Report
      2010 Annual Research Report
  • [Presentation] Saccharomyces cerevisiaeのβ-1, 6-グルカン合成関連遺伝子KRE6産物の細胞内局在と機能2011

    • Author(s)
      栗田朋和, 野田陽一, 高木智子, 大隅正子, 依田幸司
    • Organizer
      日本農芸化学会2011年度大会
    • Place of Presentation
      京都女子大学
    • Year and Date
      2011-03-27
    • Related Report
      2010 Annual Research Report
  • [Presentation] Saccharomyces cerevisiaeのゴルジ体に見いだされた新規タンパク質Gvp36の解析2011

    • Author(s)
      井上一郎, 稲留弘乃, 樫原裕治郎, 野田陽一, 依田幸司
    • Organizer
      日本農芸化学会2011年度大会
    • Place of Presentation
      京都女子大学
    • Year and Date
      2011-03-27
    • Related Report
      2010 Annual Research Report
  • [Presentation] Kre2ファミリーマンノース転移酵素のゴルジ体局在におけるSvp26の役割2010

    • Author(s)
      石井美奈子,原武浩,野田陽一,依田幸司
    • Organizer
      酵母遺伝学フォーラム第43回研究報告会
    • Place of Presentation
      奈良町センター
    • Year and Date
      2010-09-09
    • Related Report
      2010 Annual Research Report 2010 Final Research Report
  • [Presentation] 出芽酵母のβ-1, 6-グルカン合成関連遺伝子KRE6産物の解析2010

    • Author(s)
      栗田朋和, 野田陽一, 高木智子, 大隅正子, 依田幸司
    • Organizer
      酵母遺伝学フォーラム第43回研究報告会
    • Place of Presentation
      奈良町センター
    • Year and Date
      2010-09-09
    • Related Report
      2010 Annual Research Report
  • [Presentation] Saccharomyces cerevisiaeのゴルジ体に見いだされた新規タンパク質Gvp36の解析2010

    • Author(s)
      井上一郎, 稲留弘乃, 樫原裕治郎, 野田陽一, 依田幸司
    • Organizer
      酵母遺伝学フォーラム第43回研究報告会
    • Place of Presentation
      奈良町センター
    • Year and Date
      2010-09-09
    • Related Report
      2010 Annual Research Report
  • [Presentation] 出芽酵母ゴルジ体インヘリタンスの分子機構2010

    • Author(s)
      野田陽一
    • Organizer
      日本農芸化学会2010年度大会シンポジウム
    • Place of Presentation
      東京大学駒場キャンパス
    • Year and Date
      2010-03-30
    • Related Report
      2010 Final Research Report 2009 Annual Research Report
  • [Presentation] 出芽酵母Svp26はゴルジ体マンノース転移酵素のルーメン領域を認識し小胞体搬出アダプターとして機能する2010

    • Author(s)
      野田陽一・依田幸司
    • Organizer
      日本農芸化学会2010 年度大会一般講演
    • Place of Presentation
      東京大学駒場キャンパス
    • Year and Date
      2010-03-29
    • Related Report
      2010 Final Research Report
  • [Presentation] Kre2ファミリータンパク質のゴルジ体局在におけるSvp26の機能2010

    • Author(s)
      原武浩・石井美奈子・野田陽一・依田幸司
    • Organizer
      日本農芸化学会2010年度大会一般講演
    • Place of Presentation
      東京大学駒場キャンパス
    • Year and Date
      2010-03-29
    • Related Report
      2010 Final Research Report 2009 Annual Research Report
  • [Presentation] 出芽酵母Svp26はゴルジ体マンノース転移酵素のルーメン領域を認識し小胞体搬出アダプターとして機能する2010

    • Author(s)
      野田陽一・依田幸司
    • Organizer
      日本農芸化学会2010年度大会一般講演
    • Place of Presentation
      東京大学駒場キャンパス
    • Year and Date
      2010-03-29
    • Related Report
      2009 Annual Research Report
  • [Presentation] Saccharomyces cerevisiaeのβ-1,6-グルカン合成関連遺伝子Kre6産物の解析2010

    • Author(s)
      栗田朋和・野田陽一・依田幸司
    • Organizer
      日本農芸化学会2010年度大会一般講演
    • Place of Presentation
      東京大学駒場キャンパス
    • Year and Date
      2010-03-29
    • Related Report
      2009 Annual Research Report
  • [Presentation] 出芽酵母ゴルジ体膜蛋白質Svp26はマンノース転移酵素の局在に関与する2009

    • Author(s)
      野田陽一・依田幸司
    • Organizer
      酵母遺伝学フォーラム第42回研究報告会
    • Place of Presentation
      つくばノバホール
    • Year and Date
      2009-07-29
    • Related Report
      2010 Final Research Report 2009 Annual Research Report
  • [Presentation] 出芽酵母のゴルジ体IPC合成新規サブユニットKeilの機能解析2009

    • Author(s)
      佐藤啓介・野田陽一・依田幸司
    • Organizer
      酵母遺伝学フォーラム第42回研究報告会
    • Place of Presentation
      つくばノバホール
    • Year and Date
      2009-07-29
    • Related Report
      2009 Annual Research Report
  • [Presentation] 出芽酵母の新規必須ゴルジ体膜蛋白質Keilの解析2008

    • Author(s)
      佐藤啓介・野田陽一・依田幸司
    • Organizer
      酵母遺伝学フォーラム
    • Place of Presentation
      北海道大学
    • Year and Date
      2008-09-12
    • Related Report
      2008 Annual Research Report
  • [Presentation] Keil is an essential component of the inositol phosphorylceramide synthase of Saccharomvces cerevisiae2008

    • Author(s)
      佐藤啓介・野田陽一・依田幸司
    • Organizer
      2008 YEAST GENETICS AND MOLECULAR BIOLO GY MEETING
    • Place of Presentation
      トロント(カナダ)
    • Year and Date
      2008-07-24
    • Related Report
      2008 Annual Research Report

URL: 

Published: 2008-04-01   Modified: 2016-04-21  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi