| Project/Area Number |
20580090
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Applied microbiology
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| Research Institution | Kwansei Gakuin University |
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Principal Investigator |
FUJIWARA Shinsuke Kwansei Gakuin University, 理工学部, 教授 (90263219)
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| Co-Investigator(Renkei-kenkyūsha) |
IMANAKA Tadayuki 立命館大学, 生命科学部, 教授 (30029219)
ATOMI Haruyuki 京都大学, 工学研究科, 教授 (90243047)
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| Project Period (FY) |
2008 – 2010
|
| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2010: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2009: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2008: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | アーキア / 超好熱菌 / 環境適応 / ポリアミン / 分子シャペロニン / ストレス / プロテオーム / シャペロニン / RNAヘリカーゼ / Thermococcus / 膜脂質 / 低温ストレス / 生育依存性 / リボソーム |
|---|
| Research Abstract |
Living microorganisms face various kinds of stress and protect themselves by inducing several stress-responsive proteins. Among all microorganism, hyperthemophiles that grow above 85℃ are considered as one of most primitive microorganisms. It is unclear how hyperthermophile adapts to environmental changes such as temperature stress and nutrient starvation. In the present study, adaptation mechanisms of hyperthermophiles to environmental changes were focused and analyzed using hyperthermophilic archaeon Thermococcus kodakaraensis as a model microorganism.
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