| Budget Amount *help |
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2011: ¥260,000 (Direct Cost: ¥200,000、Indirect Cost: ¥60,000)
Fiscal Year 2010: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2009: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2008: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
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| Research Abstract |
We revealed that molluscan troponin-tropomyosin, the regulatory protein of muscle contraction, functions through the novel molecular mechanism that is different from those known for vertebrate troponin-tropomyosin. In addition, we suggested that the novel mechanism is present in arthropods and echinoderms and ubiquitous for invertebrate animals. Furthermore, we revealed that molluscs express various isoforms of the regulatory proteins, the biochemical properties of which are significantly different from each other. We proposed that the presence of these isoforms should be associated with the temperature adaptation of the molluscs and the difference of the locomotor habits of molluscan species.
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