Establishment of Detection Method of Endocrine Disrupter by Avian Yolk-Related Gene Expression
| Project/Area Number |
20580307
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Applied animal science
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| Research Institution | Shizuoka University |
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Principal Investigator |
MORI Makoto Shizuoka University, 農学部, 教授 (90143411)
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| Project Period (FY) |
2008 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2010: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2008: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | 代謝 / 内分泌制御 / 畜産学 / 内分泌 / 発生・分化 / 家禽 / 内分泌撹乱 / ウズラ / ホルモン / 肝臓 / 卵黄 |
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| Research Abstract |
A sensitive method by using the gene expression related to avian yolk protein was established to detect the effect of endocrine disrupters. Especially focusing on oogenesis and embryonic growth, the most appropriate gene is suggested to be quail very-low-density-lipoprotein. The effect of heavy metals and antioxidants as well as diethylstilbestrol was examined with the causal relationship with dose-related manner at molecular level.
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Report
(4 results)
Research Products
(38 results)
