Development and characterization of genetic markers in goat : Application for QTL analysis of cashmere production used developed-genetic markers.
| Project/Area Number |
20580314
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Applied animal science
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| Research Institution | Tokyo University of Agriculture |
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Principal Investigator |
YOKOHAMA Michinari Tokyo University of Agriculture, 生物産業学部, 教授 (40220561)
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| Co-Investigator(Renkei-kenkyūsha) |
KIKKAWA Yoshiaki 東京農業大学, 生物産業学部, 准教授 (20280787)
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| Research Collaborator |
SEKI Yuta 東京農業大学, 大学院・生物産業学研究科, 博士後期課程
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| Project Period (FY) |
2008 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2008: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | 育種 / 遺伝子マーカー / マイクロサテライト / ヤギ / カシミヤ / QTL / カシミヤ毛 / タイプIIケラチン / IGF1 / ケラチン |
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| Research Abstract |
To date, goat genetic markers have been limited in number compared with those of other livestock. To increase the number of potentially useful goat genetics studies, we isolated microsatellite sequences from the goat genome. A total of 260 new microsatellites were successfully optimised as genetic markers. Next, we performed QTLanalysis to identify loci associated with cashmere production used developed geneticmarkers. The QTL analysis showed that markers on chromosome 5 were suggestive linked to cashmere production. Given its genomic localization and its involvement in the hair production in mammals, the IGF1 and type II keratin genes were the candidate gene for the goat cashmere production.
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Report
(4 results)
Research Products
(18 results)
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[Journal Article] Genetic structure of Monglian goat populations using mctosatelllite loci.2008
Author(s)
Takahashi, H., Nyamsamba, D., Mandakh, B., Zagdsuren, Y., Amano, T., Nomura, K., Yokohama, M., Ito, S., Minezawa, M
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Journal Title
Asian Australas.J.Anim.Sci. 21
Pages: 947-953
Related Report
Peer Reviewed
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[Presentation] 遺伝解析に基づくヤギカシミヤ毛生産に関与するQTLの検出2009
Author(s)
関優太, 石川大樹, 鏡味優介, 相良嘉彦, 藤田優, 名倉義夫, 小谷麻衣, 野村こう, 菅野雅子, 天野卓, 横濱道成, 吉川欣亮
Organizer
日本遺伝学会第81回大会
Place of Presentation
信州大学理学部(松本)
Year and Date
2009-09-17
Related Report
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