Project/Area Number |
20580314
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Applied animal science
|
Research Institution | Tokyo University of Agriculture |
Principal Investigator |
YOKOHAMA Michinari Tokyo University of Agriculture, 生物産業学部, 教授 (40220561)
|
Co-Investigator(Renkei-kenkyūsha) |
KIKKAWA Yoshiaki 東京農業大学, 生物産業学部, 准教授 (20280787)
|
Research Collaborator |
SEKI Yuta 東京農業大学, 大学院・生物産業学研究科, 博士後期課程
|
Project Period (FY) |
2008 – 2010
|
Project Status |
Completed (Fiscal Year 2010)
|
Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2008: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
|
Keywords | 育種 / 遺伝子マーカー / マイクロサテライト / ヤギ / カシミヤ / QTL / カシミヤ毛 / タイプIIケラチン / IGF1 / ケラチン |
Research Abstract |
To date, goat genetic markers have been limited in number compared with those of other livestock. To increase the number of potentially useful goat genetics studies, we isolated microsatellite sequences from the goat genome. A total of 260 new microsatellites were successfully optimised as genetic markers. Next, we performed QTLanalysis to identify loci associated with cashmere production used developed geneticmarkers. The QTL analysis showed that markers on chromosome 5 were suggestive linked to cashmere production. Given its genomic localization and its involvement in the hair production in mammals, the IGF1 and type II keratin genes were the candidate gene for the goat cashmere production.
|