Expression of Toll-like receptor and avian b-defensin in response to bacterium in Japanese quail

• Project/Area Number: 20580327
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Basic veterinary science/Basic zootechnical science
• Research Institution: Tokyo University of Agriculture
• Principal Investigator: HARA Hiromi Tokyo University of Agriculture, 農学部, 講師 (00343567)
• Project Period (FY): 2008 – 2010
• Project Status: Completed (Fiscal Year 2010)
• Budget Amount: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000); Fiscal Year 2010: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000); Fiscal Year 2009: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000); Fiscal Year 2008: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
• Keywords: ニホンウズラ / 自然免疫 / TLR / 腸内細菌 / IgG / 16S rDNA / TLR2 / TLR4 / 幼雛 / 偽好酸球顆粒 / 抗菌活性 / 抗体 / mRNA / 正常血漿IgG濃度

Research Abstract

It was shown that the expression of each molecule which becomes the go-between of the acquired immunity from the innate immunity in the early stages ofchick related to the intestinal flora colonization and they activation becomes a trigger.