Characterization and physiological significance of the interaction between mannan-binding protein and matrix metalloproteases.
| Project/Area Number |
20590074
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Biological pharmacy
|
|---|
| Research Institution | Ritsumeikan University |
|---|
Principal Investigator |
KAWASAKI Nobuko Ritsumeikan University, 総合理工学研究機構, 教授 (70077676)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
KAWASAKI Toshisuke 立命館大学, 総合理工学研究機構, 教授 (50025706)
|
|---|
| Project Period (FY) |
2008 – 2010
|
| Project Status |
Completed (Fiscal Year 2010)
|
| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2010: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2009: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2008: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
|
|---|
| Keywords | マンナン結合タンパク質 / マンナン結合レクチン / メプリン / マトリックスメタロプロテアーゼ / レクチン / 糖鎖 / 補体活性化 / 腎虚血再灌流 / マンノース結合レクチン / 酵素 / 糖タンパク質 |
|---|
| Research Abstract |
The molecular mechanism of the interaction between a Ca^<2+>-dependent lectin, mannanbinding protein (MBP) and metalloproteases, meprins and its functional roles in the ischemia/reperfusion-operated mouse kidneys were studied.
|
Report
(4 results)
Research Products
(44 results)
-
[Journal Article] Dendritic cellspecific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN) recognizes a novel ligand, Mac-2-binding protein, characteristically expressed on human colorectal carcinomas2011
Author(s)
M.Nonaka, BY.Ma, H.Imaeda, K.Yamaguchi, N.Kawasaki, K.Hodohara, N.Kawasaki, A.Andoh, Y.Fujiyama, T.Kawasaki
-
Journal Title
Journal of Biological Chemistry(First Published Online on April 22, 2011) (in press)
Related Report
Peer Reviewed
-
-
-
-
-
[Journal Article] Highly Fucosylated N-Glycan Ligands for Mannan-binding Protein Expressed Specifically on CD26 (DPPVI) Isolated from a Human Colorectal Carcinoma Cell Line, SW1116.2009
Author(s)
N.Kawasaki, C-W.Lin, R.Inoue, K-H.Koo, N.Kawasaki, B-Y.Ma, S.Oka, M.Ishiguro, T.Sawada, H.Ishida, T.Hashimoto, T.Kawasaki
-
Journal Title
Glycobiology 19
Pages: 437-450
Related Report
Peer Reviewed
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
