| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2010: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2009: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2008: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
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| Research Abstract |
To investigate the possible influence of the polymorphism of the estrogen receptor-β gene against menopausal disease and rheumatoid arthritis (RA). As a result, it was found that CA repeat polymorphism affected on the sensitivity to a Kampo-drug, keishibukuryogan. On the other hand, Rsa polymorphism was revealed to have significant relationship to RA severity. These results could contribute to improve the clinical use of drugs based on gender specific medicine.
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