| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2008: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
|
|---|
| Research Abstract |
In this study, we investigated the possibility whether microglia can be used for brain-targeting drug delivery system, since it was reported that microglia is able to enter the brain from blood flow. At first, we studied the effect of nucleotides on the migration of microglia in our assay system. We found that adenosine triphosphate (ATP), thymidine triphosphate (TTP) and cytidine triphosphate (CTP) induced the migration of microglia.
|
