| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2009: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2008: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
|
|---|
| Research Abstract |
Since 2004, we have worked to make the zebrafish a new genetic model to unravel the function of candidate gene involved in lymphangiogenesis. As the first step, we have compiled the developing anatomical atlas of the lymphatic vascular system from the embryo through the adult. We established EGFP transgenic lines whose have lethal defects on the formation of lymphatic vascular system, and revealed the cause of defects morphologically using 2-photon laser microscope. Based on the observations, Weinstein's lab of NIH showed that chemokine signaling provides a crucial guidance cue directing early lymphatic vascular formation (submitted).
|
