Application of transposon based transgene technique for mammals
| Project/Area Number |
20590190
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
General anatomy (including Histology/Embryology)
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| Research Institution | Osaka University |
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Principal Investigator |
YAGITA Kazuhiro Osaka University, 医学研究科, 教授 (90324920)
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| Project Period (FY) |
2008 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2009: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2008: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | トランスポゾン / 概日リズム / ES細胞 / Tol2 / 生体リズム / iPS細胞 / 発生 / 遺伝子導入 / 分化 / 細胞時計 / 遺伝子導入法 |
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| Research Abstract |
Circadian clock resides in most of cells in our body, and it is important to observe the circadian clock oscillation in various functional tissues. In this study, using Tol2 transposon based vector, we have succeeded to observe the development of circadian oscillator during the ES cell differentiation in vitro.
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Report
(4 results)
Research Products
(22 results)
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[Journal Article] Development of circadian oscillator during differentiation of mouse embryonic stem cell in vitro.2010
Author(s)
Yagita K, Horie K, Koinuma S, Nakamura W, Yamanaka I, Urasaki A, Shigeyoshi Y, Kawakami K, Shimada S, Takeda J, Uchiyama Y
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Journal Title
Proc.Natl.Acad.Sci.USA 107
Pages: 3846-3851
Related Report
Peer Reviewed
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