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Effect of green odor on physiological responses to mental stress in humans

Research Project

Project/Area Number 20590231
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Environmental physiology (including Physical medicine and Nutritional physiology)
Research InstitutionShimane University

Principal Investigator

SHIDO Osamu  Shimane University, 医学部, 教授 (40175386)

Co-Investigator(Kenkyū-buntansha) MATSUZAKI Kentaro  島根大学, 医学部, 助教 (90457185)
KATAKURA Masanori  島根大学, 医学部, 助教 (40383179)
HASHIMOTO Michio  島根大学, 医学部, 准教授 (70112133)
Project Period (FY) 2008 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2008: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Keywordsみどりの香り / (Z)-3-hexenol / (E)-2-hexenal / ACTH / 体温調節 / Stroop Color-Word Test / 指先血流量 / 隔離ストレス / 精神ストレス / 医療現場 / コルチゾール
Research Abstract

We investigated the influence of green odor (a mixture of equal amounts of (Z)-3-hexenol and (E)-2-hexenal diluted to 0.03% (w/w)) administration on various physiological responses to two types of mild mental stress in human subjects. Stroop Color-Word Test significantly reduced finger blood flow and cutaneous temperature, and raised palmer sweating rate. These responses were clearly attenuated by green odor inhalation. In addition, green odor tended to depress plasma ACTH level after the mental stress. During 24-h isolation in a hospital room, green odor spray significantly lowered rectal temperature of subjects only during sleeping time. At the end of isolation, plasma glucose level was significantly elevated by green odor treatments. These results suggest a good possibility that green odor inhalation may attenuate physiological responses to acute mild mental stress in humans.

Report

(4 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (36 results)

All 2011 2010 2009 2008 Other

All Journal Article (10 results) (of which Peer Reviewed: 10 results) Presentation (24 results) Book (1 results) Remarks (1 results)

  • [Journal Article] Proliferation of neuronal progenitor cells and neuronal diggerentiation in the hypothalamus are enhanced in heat-acclimated rats.2009

    • Author(s)
      Kentaro Matsuzaki, Masanori Katakura, Toshiko Hara, Guanghua Li, Michio Hashimoto, Osamu Shido
    • Journal Title

      Pfugers Arch-Eur J Physiol Vol.458

      Pages: 661-673

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Docosahexaenoic acid promotes neuronal differentiation by regulating basic helix-loop-helix transcription factors and cell cycle in neural stem cells.2009

    • Author(s)
      Katakura M, Hashimoto M, H.M.Shahdat, S.Gamoh, T Okui, Kentaro Matsuzaki, Shido O
    • Journal Title

      Neuroscience Vol.160

      Pages: 651-660

    • NAID

      120006938660

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Docosahexaenoic acid promotes neuronal differentiation by regulating basic helix-loop-helix transcription factors and cell cycle in neural stem cells.2009

    • Author(s)
      M.Katakura, M.Hashimoto, H.M. Shahdat, S.Gamoh, T.Okui, K.Matsuzaki, O.Shido
    • Journal Title

      Neuroscience 160(3)

      Pages: 651-660

    • NAID

      120006938660

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Long-term administration of green tea catechins increases antioxidative actions and enhances neurogenesis in the hippocampus of rats.2009

    • Author(s)
      Himi, M.Hashimoto, M.Katakura, A.M.Haque, Y.Hara, O.Shido
    • Journal Title

      Cur Top Nutraceutical Res 7(3/4)

      Pages: 131-140

    • NAID

      120006938674

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Proliferation of neuronal progenitor cells and neuronal differentiation in the hypothalamus are enhanced in heat-acclimated rats.2009

    • Author(s)
      K.Matsuzaki, M.Katakura, T.Hara, G.Li, M.Hashimoto, O.Shido.
    • Journal Title

      Pflugers Arch 458(4)

      Pages: 661-673

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Mechanism of docosahexaenoic acid- induced inhibition of in vitro Aβ_(1-42) fibrillation and Aβ_(1-42)-induced toxicity in SH-SY5Y cells.2009

    • Author(s)
      S.Hossain, M.Hashimoto, M.Katakura, K.Miwa, T.Shimada, O.Shido
    • Journal Title

      J Neurochem 111(2)

      Pages: 568-579

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Effects of docosahexaenoic acid on in vitro amyloid βpeptide 25-35 fibrillation.2009

    • Author(s)
      M.Hashimoto, H.M.Shahdat, M.Katakura, Y.Tanabe, S.Gamoh, K.Miwa, T.Shimada, O.Shido
    • Journal Title

      Biochim Biophys Acta 1791(4)

      Pages: 289-296

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Effects of redecoration of a hospital isolation room with natural materials on stress levels of denizens in cold season2008

    • Author(s)
      Hiromi Ohta, Megumi Maruyama, Yoko Tanabe, Toshiko Hara, Yoshihiko Nishino, Yoshio Tsujino, Eishin Morita, Shotai Kobayashi, Osamu Shido
    • Journal Title

      Int J Biometeorol Vol.52

      Pages: 331-340

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Proliferation of neuronal progenitor cells and neuronal differentiation in the hypothalamus are enhanced in heat-acclimated rats.

    • Author(s)
      Matsuzaki K., et al.
    • Journal Title

      Pflugers Arch (in press)

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Docosahexaenoic Acid Promotes Neuronal Differentiation by Regulating Basic Hellx-Loop-Helix Transcription Factors and Cell Cycle in Neural Stem Cells.

    • Author(s)
      Katakura M, et al.
    • Journal Title

      Neuroscience (in press)

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Presentation] Anapyrexia in endotherm2011

    • Author(s)
      Shido Osamu, Matsuzaki Kentaro, Katakura Masanori, Tanabe Yoko, Hara Toshiko
    • Organizer
      第88回日本生理学会大会
    • Place of Presentation
      横浜市
    • Year and Date
      2011-03-28
    • Related Report
      2010 Final Research Report
  • [Presentation] Neuronal phenotype and localization of heat exposure-generated newborn neurons in the hypothalamus of rats.2011

    • Author(s)
      Matsuzaki Kentaro, Katakura Masanori, Hara Toshiko, Li Guanghua, Hashimoto Michio, Shido Osamu
    • Organizer
      第88回日本生理学会大会
    • Place of Presentation
      横浜市
    • Year and Date
      2011-03-28
    • Related Report
      2010 Final Research Report
  • [Presentation] Mechanism of docosahexaenoic acid-induced inhibition of in vitro amyloid β-induced fibrillation and toxicity in neuronal cells.2011

    • Author(s)
      Hashimoto Michio, Shahdat Hosssain, Katakura Masanori, Shido Osamu
    • Organizer
      第88回日本生理学会大会
    • Place of Presentation
      横浜市
    • Year and Date
      2011-03-28
    • Related Report
      2010 Final Research Report
  • [Presentation] Green tea catechins prevet memory impairment in Alzheimer's diseases model rats by decreasing amyloid βlevels and oxidative stress in cerebral cortex.2010

    • Author(s)
      Abdul Haque, Michio Hashimoto, Kentaro Matsuzaki, Osamu Shido
    • Organizer
      第62回日本生理学会中国四国地方会
    • Place of Presentation
      出雲
    • Year and Date
      2010-11-21
    • Related Report
      2010 Final Research Report
  • [Presentation] 長期暑熱馴化形成時に視床下部で新生した神経細胞の機能性解析2010

    • Author(s)
      松崎健太郎, 片倉賢紀、井上隆之、Abdul Haque, 原俊子, 橋本道男、紫藤治
    • Organizer
      第62回日本生理学会中国四国地方会
    • Place of Presentation
      出雲
    • Year and Date
      2010-11-21
    • Related Report
      2010 Final Research Report
  • [Presentation] "みどりの香り"が精神的ストレスに対する生理的応答へ及ぼす影響2010

    • Author(s)
      吉岡みち子, 松崎健太郎, 田邊洋子, 片倉賢紀、原俊子, 紫藤治
    • Organizer
      第49回日本生気象学会大会
    • Place of Presentation
      東京
    • Year and Date
      2010-11-06
    • Related Report
      2010 Final Research Report
  • [Presentation] 暑熱曝露によるラット視床下部神経新生と暑熱馴化形成の加齢変化2010

    • Author(s)
      松崎健太郎, 片倉賢紀、原俊子, 紫藤治
    • Organizer
      第49回日本生気象学会大会
    • Place of Presentation
      東京
    • Year and Date
      2010-11-06
    • Related Report
      2010 Final Research Report
  • [Presentation] "みどりの香り"が精神的ストレスに対する生理的応答へ及ぼす影響2010

    • Author(s)
      吉岡みち子, 松崎健太郎, 田邊洋子, 片倉賢紀, 原俊子, 紫藤治
    • Organizer
      第49回日本生気象学会大会
    • Place of Presentation
      文化女子大学(東京)
    • Year and Date
      2010-11-06
    • Related Report
      2010 Annual Research Report
  • [Presentation] 暑熱馴化によるラット唾液分泌促進の分子メカニズム2010

    • Author(s)
      松崎健太郎、杉本直俊、片倉賢紀、原俊子、橋本道男、紫藤治
    • Organizer
      平成22年度生理研研究会「温熱生理研究会」
    • Place of Presentation
      岡崎
    • Year and Date
      2010-09-09
    • Related Report
      2010 Final Research Report
  • [Presentation] Effects of polyunsaturated fatty acids on the cell cycle and the expression of bHLH transcription factors in neural stem cells.2010

    • Author(s)
      Katakura M, Hashimoto M, Okui T, Shido O
    • Organizer
      9th Congress of the International Society for the Study of Fatty Acids & Lipis incorporating the 8th international congress on Essential Fatty Acids and Eicosanoids and the 5th PUFA in Maternal and infant Health meeting.
    • Place of Presentation
      Maastricht, The Netherlands
    • Related Report
      2010 Final Research Report
  • [Presentation] Anapyrexia in endotherm.2010

    • Author(s)
      Osamu Shido, Kentaro Matsuzaki, Masanori Katakura, Yoko Tanabe, Toshiko Hara
    • Organizer
      The 87th Annual Meeting of the Physiological Society of Japan.
    • Place of Presentation
      Morioka, Iwate
    • Related Report
      2010 Final Research Report
  • [Presentation] Neuronal phenotype and localization of heat exposure-generated newborn neurons in the hypothalamus of rats.2010

    • Author(s)
      Kentaro Matsuzaki, Masanori Katakura, Toshiko Hara, Guanghua Li, Michio Hashimoto, Osamu Shido
    • Organizer
      The 87th Annual Meeting of the Physiological Society of Japan.
    • Place of Presentation
      Morioka, Iwate
    • Related Report
      2010 Final Research Report
  • [Presentation] Effect of polyunsaturated fatty acids on the cell cycle and the expression of bHLT transcriptional factors in niural trem cells.2009

    • Author(s)
      Masanori Katakura, Michio Hashimoto, Shuji Gamoh, Toshiyuki Okui, Kentaro Matsuzaki, Osamu Shido
    • Organizer
      The 36th congress of the international Union of Physiological Sciences.
    • Place of Presentation
      Kyoto
    • Year and Date
      2009-07-27
    • Related Report
      2010 Final Research Report
  • [Presentation] 暑熱曝露によるラット視床下部神経新生の加齢による変化2009

    • Author(s)
      松崎健太郎, 片倉賢紀, 原俊子, 李光華, 紫藤治
    • Organizer
      第48回日本生気象学会大会
    • Place of Presentation
      つくば市
    • Related Report
      2010 Final Research Report
  • [Presentation] ラット視床下部における暑熱曝露による神経新生の加齢変化2009

    • Author(s)
      松崎健太郎, 片倉賢紀, 原俊子, 李光華, 橋本道男, 紫藤治
    • Organizer
      第61回日本生理学会中国四国地方会
    • Place of Presentation
      宇部市
    • Related Report
      2010 Final Research Report
  • [Presentation] 「省エネ型体温調節」暑熱馴化の意義-個体レベルと社会レベルの観点から2009

    • Author(s)
      紫藤治, 松崎健太郎, 片倉賢紀, 丸山めぐみ, 李光華
    • Organizer
      平成21年度体温調節、温度受容研究会
    • Place of Presentation
      岡崎市
    • Related Report
      2010 Final Research Report
  • [Presentation] Possible central mechanism of long-term heat acclimation.2009

    • Author(s)
      松崎健太郎
    • Organizer
      The 3rd International Symposium on Physiology and Pharmacology of Temperature Regulation.
    • Place of Presentation
      松江
    • Related Report
      2010 Final Research Report
  • [Presentation] Modification of proliferation and defferentiation of hypothalamus progenitor cells by exercise in adult rats.2009

    • Author(s)
      Li G, Matsuzaki K, Katakura M, Hara T, Shido O
    • Organizer
      The 3rd International Symposium on Physiology and Pharmacology of Temperature Regulation.
    • Place of Presentation
      松江
    • Related Report
      2010 Final Research Report
  • [Presentation] 脳底動脈における血管収縮物質による収縮後・弛緩反応はEDHF が介在する2009

    • Author(s)
      Enkhjaragal Budbazar, 橋本道男, 坂井泰, 紫藤治
    • Organizer
      第82回日本薬理学会年会
    • Place of Presentation
      横浜
    • Related Report
      2010 Final Research Report
  • [Presentation] Docosahexaenoic acid attenuates in vitro AB fibrillation with concomitant decreases of AB peptide levels in brain of AD model rats.2009

    • Author(s)
      M Hashimoto, S.Hossain, M Katakura, Y Tanabe, S Gamoh, O Shido
    • Organizer
      9^<th> International Conference AD/PD 2009.
    • Place of Presentation
      Prague, Czech Republic
    • Related Report
      2010 Final Research Report
  • [Presentation] The protective effects of prescription omega-3 Ffatty acids on the impairment of spatial cognition learning ability in amyloid β-infused rats.2009

    • Author(s)
      S.Nishimoto, Hashimoto M, R.Tozawa, M.Katakura, S.Hossain, A.Haque, O.Shido
    • Organizer
      9^<th> International Conference AD/PD 2009.
    • Place of Presentation
      Prague, Czech Republic
    • Related Report
      2010 Final Research Report
  • [Presentation] ドコサヘキサエン酸による神経幹細胞のbHLH転写因子の発現量と細胞周期の変化2008

    • Author(s)
      片倉賢紀、橋本道男、松崎健太郎、紫藤治
    • Organizer
      第60回日本生理学会中国四国地方会
    • Place of Presentation
      愛媛
    • Year and Date
      2008-11-15
    • Related Report
      2010 Final Research Report
  • [Presentation] 運動トレーニングによる視床下部神経前駆細胞の分裂と分化2008

    • Author(s)
      李光華、松崎健太郎、片倉賢紀、原俊子、紫藤治
    • Organizer
      第47回日本生気象学会大会
    • Place of Presentation
      奈良
    • Related Report
      2010 Final Research Report
  • [Presentation] ラット暑熱馴化の成立に視床下部神経前駆細胞の分裂と分化が関与する可能性2008

    • Author(s)
      松崎健太郎、片倉賢紀、丸山めぐみ、原俊子、橋本道男、紫藤治
    • Organizer
      平成20年度生理研研究会「体温調節、温度受容研究会」
    • Place of Presentation
      岡崎
    • Related Report
      2010 Final Research Report
  • [Book] からだの温度の事典(B.臨床医学(編集))2010

    • Author(s)
      紫藤治, 他
    • Publisher
      朝倉書店、東京
    • Related Report
      2010 Final Research Report
  • [Remarks] ホームページ等

    • Related Report
      2010 Final Research Report

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Published: 2008-04-01   Modified: 2016-04-21  

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