| Budget Amount *help |
¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Fiscal Year 2011: ¥390,000 (Direct Cost: ¥300,000、Indirect Cost: ¥90,000)
Fiscal Year 2010: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2009: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2008: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
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| Research Abstract |
In this study, we demonstrate that deletion of 8p22-23 is not only an important event in the initiation and/or promotion of hepatocellular carcinoma, but also closely associated with subsequent progression, especially during metastasis. The part of results was collected in Genetic Alteration in Cancer database of NIH. On the other hand, we found that PROM1, which was usually recognized as a marker of cancer stem cell, might be have a function as tumor suppressor gene in the hepatogenesis.
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