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Analysis of Uropathogenic-specific protein and development of the mucosal vaccine by using of USP

Research Project

Project/Area Number 20590436
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Bacteriology (including Mycology)
Research InstitutionObihiro University of Agriculture and Veterinary Medicine

Principal Investigator

KURAZONO Hisao  Obihiro University of Agriculture and Veterinary Medicine, 畜産学部, 教授 (90186487)

Co-Investigator(Kenkyū-buntansha) YAMAMOTO Shingo  兵庫医科大学, 医学部, 教授 (80322741)
YAMASAKI Eiki  帯広畜産大学, 畜産学部, 助教 (40514708)
Project Period (FY) 2008 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2010: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2009: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2008: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywords病原性 / 粘膜ワクチン / 細菌 / 尿路感染症 / 蛋白質 / 免疫学 / 粘膜 / 感染症
Research Abstract

Uropathogenic-specific protein (USP) is one of the important virulence factors in UPEC. We established a highly-sensitive bead-ELISA system against USP. The minimum detection concentration of USP in the sample is 100 pg/ml. By using of this detection system, we try to clarify the relationship between the production of USP in UPEC and the symptoms of the patients suffered from UPEC infections.

Report

(4 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (84 results)

All 2011 2010 2009 2008 Other

All Journal Article (48 results) (of which Peer Reviewed: 24 results) Presentation (35 results) Remarks (1 results)

  • [Journal Article] Helicobacter pylori VacA reduces cellular expression of STAT3 and pro-survival Bcl-2 family proteins, Bcl-2 and Bcl-X_L, leading to apoptosis in gastric epithelial cells.2011

    • Author(s)
      Matsumoto A, Kurazono H, Kohno S
    • Journal Title

      Digestive Diseases and Science 56

      Pages: 999-1006

    • Related Report
      2010 Final Research Report
  • [Journal Article] Hybrid & El Tor variant biotypes of Vibrio cholerae Ol in Thailand2011

    • Author(s)
      Na-Ubol M, Kurazono H, Chaicumpa W
    • Journal Title

      Indian J.Med.Res. 133

      Pages: 387-394

    • Related Report
      2010 Final Research Report
  • [Journal Article] Double short-time exposure to pirarubicin produces higher cytotoxity against T24 bladder cancer cells.2011

    • Author(s)
      Maruyama T, Yamamoto S, Shima H
    • Journal Title

      J.Infect.Chemother. 17

      Pages: 11-16

    • NAID

      10027816598

    • Related Report
      2010 Final Research Report
  • [Journal Article] A single-dose regimen for antimicrobial prophylaxis to prevent perioperative infection in urological clean and clean-contaminated surgery.2011

    • Author(s)
      Higuchi Y, Takesue Y, Yamamoto S
    • Journal Title

      J.Infect.Chemother. 17

      Pages: 219-222

    • NAID

      10028171475

    • Related Report
      2010 Final Research Report
  • [Journal Article] Helicobacter pylori VacA reduces cellular expression of STAT3 and pro-survival Bcl-2 family proteins, Bcl-2 and Bcl-X_L, leading to apoptosis in gastric epithelial cells2011

    • Author(s)
      Matsumoto A, Isomoto H, Nakayama M, Hisatsune J, Nishi Y, Nakashima Y, Matsushima K, Kurazono H, Nakao K, Hirayama T, Kohno S
    • Journal Title

      Digestive Diseases and Science

      Volume: 56 Pages: 999-1006

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Hybrid & EI Tor variant biotypes of Vibrio cholerae O1 in Thailand2011

    • Author(s)
      Na-Ubol, M, Srimanote P, Chongsa-nguan M, Indrawattana N, Sookrung N, Tapchaisri P, Yamazaki S, Bodhidatta L, Eampokalap B, Kurazono H, Hayashi H, Nair GB, Takeda Y, Chaicumpa W
    • Journal Title

      Indian Journal of Medical Research

      Volume: 133 Pages: 387-394

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A single-dose regimen for antimicrobial prophylaxis to prevent perioperative infection in urological clean and clean-contaminated surgery2011

    • Author(s)
      Higuchi Y, Takesue Y, Yamada Y, Ueda Y, Suzuki T, Aihara K, Mane yama T, Kondoh N, Nojima M, Yamamoto S
    • Journal Title

      Journal of Infection and Chemotheraphy

      Volume: 17 Pages: 219-222

    • NAID

      10028171475

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Double short-time exposure to pirarubicin produces higher cytotoxity against T24 bladder cancer cells2011

    • Author(s)
      Maruyama T, Higuchi Y, Suzuki T, Qiu J, Yamamoto S, Shima H
    • Journal Title

      Journal of Infection and Chemotheraphy

      Volume: 17 Pages: 11-16

    • NAID

      10027816598

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The nationwide study of bacterial pathogens associated with urinary tract infections conducted by the Japanese Society of Chemotherapy2011

    • Author(s)
      Ishikawa K, Matsumoto T, Yasuda M, Uehara S, Muratani T, Yagisawa M, Sato J, Niki Y, Totsuka K, Sunakawa K, Hanaki H, Hattori R, Terada M, Kozuki T, Maruo A, Morita K, Ogasawara K, Takahashi Y, Matsuda K, Hirose T, Miyao N, Hayashi T, Takeyama K, Kiyota H, Tomita M, Yusu H, Koide H, Kimura S, Yanaoka M, Sato H, Ito T, Deguchi T, Fujimoto Y, Komeda H, Asano Y, Takahashi Y, Ishihara S, Arakawa S, Nakano Y, Tanaka K, Fujisawa M, Matsui T, Fujii A, Yamamoto S, Nojima M, Higuchi Y, Ueda Y, Kanamaru S, Monden K, Tsushima T, Seno Y, Tsugawa M, Takenaka T, Hamasuna R, Fujimoto N, Sho T, Takahashi K, Inatomi H, Takahashi N, Ikei Y, Hayami H, Yamane T, Nakagawa M, Kariya S, Arima T
    • Journal Title

      Journal of Infection and Chemotheraphy

      Volume: 17 Pages: 126-138

    • NAID

      10027816979

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A V_HH that neutralizes the zinc-metalloproteinase activity of botulinum neurotoxin type A.2010

    • Author(s)
      Thanongsaksrikul J, Kurazono H, Chaicumpa W
    • Journal Title

      J.Biol.Chem. 285

      Pages: 9657-9666

    • Related Report
      2010 Final Research Report
  • [Journal Article] Helicobacter pylori CagA Inhibits Endocytosis of Cytotoxin VacA in Host Cells.2010

    • Author(s)
      Akada KJ, Kurazono H, Nakamura K
    • Journal Title

      Disease Models & Mechanisms 3

      Pages: 605-617

    • Related Report
      2010 Final Research Report
  • [Journal Article] Far-infrared rays control prostate cancer cells in vitro and in vivo.2010

    • Author(s)
      Shima H, Yamamoto S
    • Journal Title

      Cent.Eur.J.Biol. 5

      Pages: 178-189

    • Related Report
      2010 Final Research Report
  • [Journal Article] Prognostic of Japanese metastatic renal cell carcinoma (mRCC) patients in the cytokine era-a cooperative group report of 1,463 mRCC patients.2010

    • Author(s)
      Naito S, Yamamoto S, Tomita Y
    • Journal Title

      Eur.Urol. 57

      Pages: 317-315

    • Related Report
      2010 Final Research Report
  • [Journal Article] A transient increase of calcineurin phosphatase activity in living-donor kidney transplant recipient with acute rejection.2010

    • Author(s)
      Fukudo M, Yamamoto S, Inui K
    • Journal Title

      Drug Metab.Pharmacokinet 25

      Pages: 411-417

    • NAID

      10027583568

    • Related Report
      2010 Final Research Report
  • [Journal Article] The antitumour effect of γδ T Cells is enhanced by valproic acid-induced up-regulation of NKG2D ligands.2010

    • Author(s)
      Suzuki T, Terao S, Acharya B, Naoe M, Yamamoto S, Okamura H, Gotoh A
    • Journal Title

      Anticancer Res. 30

      Pages: 4509-4514

    • Related Report
      2010 Final Research Report
  • [Journal Article] Direct binding of gangliosides to Helicobacter pylori vacuolating cytotoxin (VacA) neutralizes its toxin activity.2010

    • Author(s)
      Wada A, Yamasaki E, Senba M
    • Journal Title

      Glycobiology 20

      Pages: 668-678

    • NAID

      120006984983

    • Related Report
      2010 Final Research Report
  • [Journal Article] A V_HH that neutralizes the zinc-metalloproteinase activity of botulinum neurotoxin type A2010

    • Author(s)
      Thanongsaksrikul J, Srimanote P, Maneewatch S, Choowongkomon K, Tapchaisri P, Makino S-I, Kurazono H, Chaicumpa W
    • Journal Title

      Journal of Biological Chemistry

      Volume: 285 Pages: 9657-9666

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Helicobacter pylori CagA Inhibits Endocytosis of Cytotoxin VacA in Host Cells2010

    • Author(s)
      Akada KJ, Aoki H, Torigoe Y, Kitagawa T, Kurazono H, Hoshida H, Nishikawa J, Terai S, Matsuzaki M, Hirayama T, Nakazawa T, Akada R, Nakamura K
    • Journal Title

      Disease Models & Mechanisms

      Volume: 3 Pages: 605-617

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Far-infrared rays control prostate cancer cells in vitro and in vivo2010

    • Author(s)
      Shima H, Yamamoto S, Qiu J, Shin cho M, Hirota S, Yoshikawa Y, Yoshikawa R, Hashimoto-Tamaoka T
    • Journal Title

      Central European Journal of Biology

      Volume: 5 Pages: 178-189

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Prognostic of Japanese metastatic renal cell carcinoma (mRCC) patients in the cytokine era-a cooperative group report of 1,463 mRCC patients2010

    • Author(s)
      Naito S, Yamamoto N, Takayama T, Muramoto M, Shinohara N, Nishiyama K, Takahashi A, Maruyama R, Saika T, Hoshi S, Nagao K, Yamamoto S, Sugimura I, Umemura H, Koga S, Takahashi M, Ito F, Ozono S, Terachi T, Naito S, Tomita Y
    • Journal Title

      European Journal of Urology

      Volume: 57 Pages: 317-325

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A transient increase of calcineurin phosphatase activity in living-donor kidney transplant recipient with acute rejection2010

    • Author(s)
      Fukudo M, Yano I, Katsuya T, Ito N, Yamamoto S, Kamoto T, Ogawa O, Inui K
    • Journal Title

      Drug Metab pharmacokinet

      Volume: 25 Pages: 411-417

    • NAID

      10027583568

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The antitumour effect of γ δ T Cells is enhanced by valproic acid-induced up-regulation of NKG2D ligands2010

    • Author(s)
      Suzuki T, Terao S, Acharya B, Naoe M, Yamamoto S, Okamura H, Gotoh A
    • Journal Title

      Anticancer Research

      Volume: 30 Pages: 4509-4514

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Direct binding of gangliosides to Helicobacter pylori vacuolating cytotoxin (VacA) neutralizes its toxin activity2010

    • Author(s)
      Wada A, Hasegawa M, Wong P F, Shirai E, Shirai N, Tan L J, Llanes R, Hojo H., Yamasaki E, Ichinose A, Ichinose Y, Senba M
    • Journal Title

      Glycobiology

      Volume: 20 Pages: 668-678

    • NAID

      120006984983

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A V_HH that neutralizes the zinc-metalloproteinase activity of botulinum neurotoxin type A.2010

    • Author(s)
      Thanongsaksrikul J, Srimanote P, Maneewatch S, Choowongkomom K, Tapchaisri P, Makino S-I, Kurazono H, Chaicumpa W.
    • Journal Title

      Journal of Biological Chemistry 285

      Pages: 9657-9666

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Direct binding of gangliosides to Helicobacter pylori vacuolating cytotoxin(VacA)neutralizes its toxin activity.2010

    • Author(s)
      Wada A, Hasegawa M, Wong P F, Shirai E, Shirai N, Tan L J, Llanes R, Hojo H, Yamasaki E, Ichinose A, Ichinose Y, Senba M
    • Journal Title

      Glycobiology (印刷中)

    • NAID

      120006984983

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Current therapy of acute uncomplicated cystitis.2010

    • Author(s)
      Yamamoto S, Higuchi Y, Nojima M
    • Journal Title

      International Journal of Urology (印刷中)

    • NAID

      10027258465

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Helicobacter pylori VacA-induced inhibition of GSK3 through the PI3K/Akt signaling pathway.2009

    • Author(s)
      Nakayama M, Yamasaki E, Kurazono H, Hirayama T
    • Journal Title

      J.Biol.Chem. 284

      Pages: 1612-1619

    • Related Report
      2010 Final Research Report
  • [Journal Article] Genetic profiles of fluoroquinolone-resistant Escherichia coli isolated from cystitis : phylogeny, virulence factors, PAlusp-subtypes, and mutation patterns.2009

    • Author(s)
      Takahashi A, Kurazono H, Yamamoto S
    • Journal Title

      J.Clin.Microbiol. 47

      Pages: 791-795

    • Related Report
      2010 Final Research Report
  • [Journal Article] Human monoclonal ScFv neutralize lethal Thai cobra, Naja kaouthia, neurotoxin.2009

    • Author(s)
      Kulkeaw K, Kurazono H, Chaicumpa W
    • Journal Title

      J.Proteomics 72

      Pages: 270-282

    • Related Report
      2010 Final Research Report
  • [Journal Article] Clinical efficacy of oral administration of 200 mg gatifloxacin once daily for 3 days for the treatment of patients with uncomplicated cystitis.2009

    • Author(s)
      Yamamoto S
    • Journal Title

      J.Infect.Chemother. 15

      Pages: 104-107

    • NAID

      10025128556

    • Related Report
      2010 Final Research Report
  • [Journal Article] Diagnostic accuracy of volume-rendered computed tomography movie and other computed tomography-based imaging methods in assessment of renal vascular anatomy for laparoscopic donor nephrectomy.2009

    • Author(s)
      Yamamoto S
    • Journal Title

      Int.Urol.Nephrol. 41

      Pages: 785-790

    • Related Report
      2010 Final Research Report
  • [Journal Article] Basic fibroblast growth factor causes urinary bladder overactivity trough gap junction generation in the smooth muscle.2009

    • Author(s)
      Imamura M, Yamamoto S, Ogawa O
    • Journal Title

      Am.J.Pysiol.Renal Physiol. 297

    • Related Report
      2010 Final Research Report
  • [Journal Article] Human monoclonal ScFv neutralize lethal Thai cobra, Naja kaouthia, neurotoxin.2009

    • Author(s)
      Kulkeaw K, Sakolvaree Y, Srimanote P, Tongtawe P, Maneewatch S, Sookrung N, Tungtrongchitr A, Tapchaisri P, Kurazono H, Chaicumpa W.
    • Journal Title

      Journal of Proteomics 72

      Pages: 270-282

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] ピロリ菌の空胞化毒素VacAの多機能性-感染における役割2009

    • Author(s)
      山崎栄樹, 磯本一, 平山壽哉
    • Journal Title

      蛋白質核酸酵素 54

      Pages: 607-613

    • Related Report
      2009 Annual Research Report
  • [Journal Article] Genetic profiles of fluoroquinolone-resistant Escherichia coli isolated from cystitis : phylogeny, virulence factors, PAIusp-subtypes, and mutation patterns.2009

    • Author(s)
      Takahashi A, Muratani T, Yasuda M, Takahashi S, Monden K, Ishikawa K, Kiyota H, Arakawa S, Matsumoto T, Shima, H, Kurazono H, Yamamoto S
    • Journal Title

      Journal of Clinical Microbiology 47

      Pages: 791-785

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Clinical efficacy of oral administration of 200mg gatifloxacin once daily for 3 days for the treatment of patients with uncomplicated cystitis.2009

    • Author(s)
      Yamamoto S, Akiyama K, Yoshimoto T, Kanokogi M, Yabumoto H, Ihara H, Ishikawa E, Yoshioka M, Kokura K, Hiroki Shima
    • Journal Title

      Journal of infection and chemotherapy 15

      Pages: 104-107

    • NAID

      10025128556

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Genetic profiles of fluoroquinolone-resistant Escherichia colt isolated from cystitis : phylogeny, virulence factors, PAlusp-subtypes, and mutation patterns2009

    • Author(s)
      Takahashi A, Muratani T, Yasuda M, Takahashi S, Monden K, Ishikawa K, Kiyota H, Arakawa S, Matsumoto T, Shima, H, Kurazono H. Yamamoto S
    • Journal Title

      Journal of Clinical Microbiology 47

      Pages: 791-795

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Helicobacter pylori VacA-induced inhibition of GSK3 through the PI3K/Akt signaling pathway2009

    • Author(s)
      Nakayama M, Hisatsune J, Yamasaki E, Isomoto H, Kurazono H, Hatakeyama M, Azuma T, Yamaoka Y, Yahiro K. Moss J, Hirayama T.
    • Journal Title

      Journal of Biological Chemistry 284

      Pages: 1612-1619

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Human monoclonal ScFv neutralize lethal Thai cobra, Naja kaouthia, neurotoxin2009

    • Author(s)
      Kulkeaw K, SaKolvaree Y, Srimanote P, Tongtawe P, Maneewatch S, Sookrung N, Tungtrongchitr A, Tapchaisri P, Kurazono H, Chaicumpa W
    • Journal Title

      Journal of Proteomics (印刷中)

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 【泌尿器科感染症の今日的話題-難治性要因と対応-】尿路感染症における病原因子の役割2009

    • Author(s)
      山本新吾
    • Journal Title

      化学療法の領域 25

      Pages: 404-411

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Molecular characterization of Helicobacter pylori VacA-induction of IL-8 in U937 cells reveals a prominent role for p38MAP kinase in ATF-2, CREB and NF K B activation.2008

    • Author(s)
      Hisatsune J, Kurazono H, Yamasaki E
    • Journal Title

      J.Immunol. 180

      Pages: 5017-5027

    • Related Report
      2010 Final Research Report
  • [Journal Article] Molecular typing of Vibrio cholerae O1 isolates from Thailand by pulsed-field gel electrophoresis.2008

    • Author(s)
      Tapchaisri P, Kurazono H, Chaicumpa W
    • Journal Title

      J.Health Popul.Nutr. 26

      Pages: 79-87

    • Related Report
      2010 Final Research Report
  • [Journal Article] 21-hydroxylase deficiency presenting as an adrenal incidentaloma : Endocrinological evaluation and mutational analysis.2008

    • Author(s)
      Takahashi S, Yamamoto S
    • Journal Title

      Endocrinologist 18

      Pages: 207-210

    • Related Report
      2010 Final Research Report
  • [Journal Article] Diagnostic efficacy of free to total ratio of prostate-specific antigen and prostate-specific antigen velocity, singly and in combination, in detecting prostate cancer in patients with total serum prostate-specific antigen between 4 and 10 ng/ml.2008

    • Author(s)
      Yamamoto S
    • Journal Title

      Int.Urol.Nephrol. 40

      Pages: 85-89

    • Related Report
      2010 Final Research Report
  • [Journal Article] Antibiotic prophylaxis for transrectal prostate biopsy : a prospective randomized study of tosufloxacin versus levofloxacin.2008

    • Author(s)
      Yamamoto S
    • Journal Title

      Int J Urol 15

      Pages: 604-606

    • NAID

      10021278929

    • Related Report
      2010 Final Research Report
  • [Journal Article] Salvage therapy trial for erectile dysfunction using phosphodiestrase type 5 inhibitors and vitamin E : Preliminary report.2008

    • Author(s)
      Kondoh N, Yamamoto S
    • Journal Title

      Aging Male 11

      Pages: 167-170

    • Related Report
      2010 Final Research Report
  • [Journal Article] Molecular characterization of Helicobacter pylori VacA-induction of IL-8 in U937 cells reveals a prominent role for p38MAP kinase in ATF-2, CREB and NF-κB activation2008

    • Author(s)
      Hisatsune, J., Nakayama, M., Isomoto. H., Kurazono, H., Mukaida, N., Mukhopadhyay, A. K., Sap, J, Yamasaki, E., Yahiro, Y., Moss, J., and Hirayama, T.
    • Journal Title

      Journal of Immunology 180

      Pages: 5017-5027

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Molecular typing of Vibrio cholerae O1 isolates from Thailand by pulsed-field gel electrophoresis2008

    • Author(s)
      Tapchaisri, P., Na-Ubol, M., Tiyasuttipan, W., Chaiyaroj, S. C., Yamasaki, S., Wougsaroj, T., Hayashi, H., Nair, G. B., Chougsa-nguan, M., Kurazono, H, Chaimmma, W.
    • Journal Title

      Journal of Health, Population and Nutrition 26

      Pages: 79-87

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Presentation] A randomized clinical trial to evaluate the preventive effect of cranberry juice(UR65)for patients with recurrent urinary tract infection2011

    • Author(s)
      Takahashi S, Hamasuna R, Yasuda M, Arakawa S, Tanaka K, Ishikawa K, Kiyota H, Hayami H, Yamamoto S, Matsumoto T
    • Organizer
      IICC/ECCMID 2011
    • Place of Presentation
      Milan, Italy
    • Year and Date
      2011-05-07
    • Related Report
      2010 Annual Research Report
  • [Presentation] on behalf of the Japanese UTI Research Group : A randomized clinical trial to evaluate the preventive effect of cranberry juice (UR65) for patients with recurrent urinary tract infection.2011

    • Author(s)
      Takahashi S, Hamasuna R, Yasuda M, Arakawa S, Tanaka K, Ishikawa K, Kiyota H, Hayami H, Yamamoto S, Matsumoto T
    • Organizer
      ICC/ECCMID 2011
    • Place of Presentation
      Milan, Italy
    • Related Report
      2010 Final Research Report
  • [Presentation] Analysis of Pthogenicity island of Uropathogenic Escherichia coli which encodes the USP.2010

    • Author(s)
      倉園久生倉園久生
    • Organizer
      SPU Forum : Updates on Common Viral and Bacterial Infections.
    • Place of Presentation
      Universiti Malaysia Sabah, School of Medicine
    • Year and Date
      2010-10-25
    • Related Report
      2010 Final Research Report
  • [Presentation] Analysis of Pthogenicity island of Uropathogenic Escherichia coli which encodes the USP2010

    • Author(s)
      Kurazono H
    • Organizer
      SPU Forum : Updates on Common Viral and Bacterial Infections
    • Place of Presentation
      Universiti Malaysia Sabah, Malaysia
    • Year and Date
      2010-10-25
    • Related Report
      2010 Annual Research Report
  • [Presentation] Education for Sustainable Development (ESD) on Infectious Diseases and Global Environmental Issues2010

    • Author(s)
      Smith M, Kurazono H
    • Organizer
      14^<th> UNESCO-APEID International Conference Education for Human Resource Development
    • Place of Presentation
      Imperial Queen's Park Hotel, Bangkok, Thailand
    • Year and Date
      2010-10-23
    • Related Report
      2010 Annual Research Report
  • [Presentation] Optimal treatment with antibiotics : single dose, short course(3 days), or standard course(7 days)therapy2010

    • Author(s)
      Yamamoto S
    • Organizer
      10th Asian Congress of Urology, Urological Association of Asia
    • Place of Presentation
      Taipei, Taiwan
    • Year and Date
      2010-08-29
    • Related Report
      2010 Annual Research Report
  • [Presentation] Assessment of a single-dose regimen for antimicrobial prophylaxis to prevent perioperative infection in urologic surgery2010

    • Author(s)
      Yamamoto S
    • Organizer
      German-Japanese Confederation of Urology 9th Scientific Meeting
    • Place of Presentation
      Munster, Germany
    • Year and Date
      2010-06-19
    • Related Report
      2010 Annual Research Report
  • [Presentation] Assessment of a single-dose regimen for antimicrobial prophylaxis to prevent perioperative infection in urologic surgery.2010

    • Author(s)
      Higuchi Y, Yamada Y, Ueda Y, Suzuki Y, Aihara K, Maruyama T, Nojima M, Yamamoto S
    • Organizer
      Society for Infection and Inflammation (SIIU) at AUA Annual Meeting '10.
    • Place of Presentation
      San Francisco, USA
    • Year and Date
      2010-05-30
    • Related Report
      2010 Final Research Report
  • [Presentation] Enhancement of γ δ T cell antitumor activity against prostate cancer cell through Toll-like receptor 2 and 3 ligand dependent activation2010

    • Author(s)
      Suzuki T, Tacharya B, Terao S, Nojima M, Yamamoto S, Gotoh A
    • Organizer
      AUA Annual Meeting'10
    • Place of Presentation
      San Francisco, USA
    • Year and Date
      2010-05-29
    • Related Report
      2010 Annual Research Report
  • [Presentation] Assessment of a single-dose regimen for antimicrobial prophylaxis to prevent perioperative infection in urologic surgery2010

    • Author(s)
      Higuchi Y, Yamada Y, Ueda Y, Suzuki Y, Aihara K, Maruyama T, Noiima M, Yamamoto S
    • Organizer
      AUA Annual Meeting'10
    • Place of Presentation
      San Francisco, USA
    • Year and Date
      2010-05-29
    • Related Report
      2010 Annual Research Report
  • [Presentation] Antimicrobial Prophylaxis in Urological Surgery2010

    • Author(s)
      Yamamoto S
    • Organizer
      8^<th> Annual Congress of the KAUTII
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2010-05-01
    • Related Report
      2010 Annual Research Report
  • [Presentation] 尿路病原性大腸菌の産生するUSPに対する特異的同定法の開発2010

    • Author(s)
      山崎栄樹、高橋彰、山本新吾、星英之、牧野壮一、倉園久生
    • Organizer
      第83回日本細菌学会総会
    • Place of Presentation
      パシフィコ横浜、横浜市
    • Related Report
      2010 Final Research Report
  • [Presentation] Enhancement of γδ T cell antitumor activity against prostate cancer cell through Toll-like receptor 2 and 3 ligand dependent activation.2010

    • Author(s)
      Suzuki T, Tacharya B, Terao S, Noj ima M, Yamamoto S, Gotoh A
    • Organizer
      AUA Annual Meeting '10
    • Place of Presentation
      San Francisco, USA
    • Related Report
      2010 Final Research Report
  • [Presentation] Assessment of a single-dose regimen for antimicrobial prophylaxis to prevent perioperative infection in urologic surgery.2010

    • Author(s)
      Yamamoto S
    • Organizer
      German-Japanese Confederation of Urology 9th Scientific Meeting.
    • Place of Presentation
      Munster, Germany
    • Related Report
      2010 Final Research Report
  • [Presentation] 尿路病原性大腸菌の産生するUSPに対する特異的同定法の開発2010

    • Author(s)
      山崎栄樹, 高橋彰, 山本新吾, 星英之, 牧野壮一, 倉園久生
    • Organizer
      第83回日本細菌学会総会
    • Place of Presentation
      パシフィコ横浜
    • Related Report
      2009 Annual Research Report
  • [Presentation] Diversity in the expression of Salmonella enterotoxin that has a cytotoxic effect on cultured cells by various Salmonella species.2009

    • Author(s)
      Yamasaki E, Nakano M, Hoshi H, Seto Y, Chongsa-nguan M, Chicumpa W, Nair G B, Makino S-I, Hirayama T, Kurazono H
    • Organizer
      3rd ASM Conference on Salmonella : Biology, Pathogenesis & Prevention
    • Place of Presentation
      Aix-en-Provence, フランス
    • Year and Date
      2009-10-07
    • Related Report
      2009 Annual Research Report
  • [Presentation] Diversity in the expression of Salmonella enterotoxin that has a cytotoxic effect on cultured cells by various Salmonella species.2009

    • Author(s)
      Yamasaki E, Nakano M, Hoshi H, Seto Y, Chongsa-nguan M, Chicumpa W, Nair G B, Makino S-I, Hirayama T, Kurazono H
    • Organizer
      平成21年度日米医学協力会コレラ・細菌性腸管感染症専門部会総会
    • Place of Presentation
      京都大学稲盛記念ホール
    • Year and Date
      2009-07-29
    • Related Report
      2009 Annual Research Report
  • [Presentation] The phylogenetic and virulence profiles of quinolone-resistant Escherichia coli isolated from cystitis are different from quinolone-susceptible counterparts.2009

    • Author(s)
      Yamamoto S, Takahashi A, Muratani T, Yasuda M, Takahashi S, Monden K, Ishikawa K, Kiyota H, Arakawa S, Matsumoto T, Shima H, Kurazono H
    • Organizer
      America Urology Association Annual Meeting
    • Place of Presentation
      シカゴ、米国
    • Year and Date
      2009-04-28
    • Related Report
      2009 Annual Research Report
  • [Presentation] Diversity in the expression of Salmonella enterotoxin that has a cytotoxic effect on cultured cells by various Salmonella species.2009

    • Author(s)
      Yamasaki E, Nakano M, Hoshi H, Seto Y, Chongsa-nguan M, Chicumpa W, Nair G B, Makino S-I, Hirayama T, Kurazono H
    • Organizer
      3rd ASM Conference on Salmonella : Biology, Pathogenesis & Prevention.
    • Place of Presentation
      Aix-en-Provence, France
    • Related Report
      2010 Final Research Report
  • [Presentation] The phylogenetic and virulence profiles of quinolone-resistant Escherichia coli isolated from cystitis are different from quinolone-susceptible counterparts.2009

    • Author(s)
      Yamamoto S, Takahashi A, Muratani T, Yasuda M, Takahashi S, Monden K, Ishikawa K, Kiyota H, Arakawa S, Matsumoto T, Shima H, Kurazono H
    • Organizer
      AUA Annual Meeting '09
    • Place of Presentation
      Chicago, USA
    • Related Report
      2010 Final Research Report
  • [Presentation] The antitumor effect of y6T cells against bladder cancer cells is enhanced following upregulation of NKG2D ligands by valproic acid.2009

    • Author(s)
      Foru Suzuki, Bishnu Acharya, Shuji Terao, Shingo Yamamoto, Hiroki Shima, Haruki Okamura, Akinobu Gotoh
    • Organizer
      AUA Annual Meeting '09
    • Place of Presentation
      Chicago, USA
    • Related Report
      2010 Final Research Report
  • [Presentation] Transient disappearance of donor-specific antibody on post-transplant day 1 may indicate high risk for antibody-mediated acute rejection following kidney transplantation in sensitized recipients.2009

    • Author(s)
      Ueda Y, Nojima M, Hashimoto M, Higuchi Y, Kinoshita T, Hao H, Kyo M, Ichikawa Y, Hirota S, Yamamoto S, Shima H
    • Organizer
      European Society for Organ Transplantation 2009
    • Place of Presentation
      Paris, France
    • Related Report
      2010 Final Research Report
  • [Presentation] Salmonella enterotoxin (Stn)精製法の確立及び細胞毒性解析2009

    • Author(s)
      山崎栄樹、星英之、牧野壮一、平山壽哉、倉園久生
    • Organizer
      第82回日本細菌学会総会
    • Place of Presentation
      名古屋市
    • Related Report
      2008 Annual Research Report
  • [Presentation] H. pylori VacAの細胞毒性に及ぼすSphingomyelinaseの影響2009

    • Author(s)
      久恒順三、小田真隆、櫻井純、由崎栄樹、倉園久生、平山壽哉
    • Organizer
      第82回日本細菌学会総会
    • Place of Presentation
      名古屋市
    • Related Report
      2008 Annual Research Report
  • [Presentation] Helicobacter pylori CagA inhibits VacA endocytosis during infection2009

    • Author(s)
      赤田純子、倉園久生、平山壽哉、中澤晶子、中村和行
    • Organizer
      第82回日本細菌学会総会
    • Place of Presentation
      名古屋市
    • Related Report
      2008 Annual Research Report
  • [Presentation] Proteomic analysis of growth promoting factor in Shigella flexneri2009

    • Author(s)
      川瀬摂、門田修子、倉園久生、牧野壮一、川本恵子
    • Organizer
      第82回日本細菌学会総会
    • Place of Presentation
      名古屋市
    • Related Report
      2008 Annual Research Report
  • [Presentation] 「ワークショップ : 大腸菌の病原性」尿路病原性大腸菌の病原因子2009

    • Author(s)
      山本新吾
    • Organizer
      第82回日本細菌学会総会
    • Place of Presentation
      名古屋市
    • Related Report
      2008 Annual Research Report
  • [Presentation] AAUS Symposium : Catheter Associated UTI : CAUTI European and Asian guidelines.2008

    • Author(s)
      Yamamoto S
    • Organizer
      Pre-congress meeting of the 5th Asian Association of UTI and STD
    • Place of Presentation
      Taipei, Taiwan
    • Year and Date
      2008-11-29
    • Related Report
      2010 Final Research Report
  • [Presentation] 膀胱炎由来キノロン耐性大腸菌のキノロン耐性決定領域変異と系統分類・病原因子の相関2008

    • Author(s)
      高橋彰、山本新吾、村谷哲郎、石川清仁、安田満、高橋聡、門田晃一、清田浩、荒川創一、松本哲朗
    • Organizer
      第19回尿路感染症研究会
    • Place of Presentation
      東京都
    • Year and Date
      2008-11-01
    • Related Report
      2008 Annual Research Report
  • [Presentation] Biological activities of Salmonella enterotoxin2008

    • Author(s)
      Yamasaki E, Hoshi H, Seto Y, Chongsa-nguan M, Chicumpa W, GB Nair, Makino S-I, Hirayama T, Kurazono H
    • Organizer
      平成20年度日米医学協力会コレラ・細菌性腸管感染症専門部会総会
    • Place of Presentation
      大阪市
    • Year and Date
      2008-07-30
    • Related Report
      2008 Annual Research Report
  • [Presentation] Helicobacter pylori VacA-induced IL-8 production in U937 cells is mediated by an increase in intracellular Ca2+, followed by activation of ATF-2, CREB and NF-kB2008

    • Author(s)
      Toshiya Hirayama, Jyunzo Hisatsune, Eiki Yamasaki, Hisao Kurazono, Kinnosuke Yahiro, and Joel Moss
    • Organizer
      平成20年度日米医学協力会コレラ・細菌性腸管感染症専門部会総会
    • Place of Presentation
      大阪市
    • Year and Date
      2008-07-30
    • Related Report
      2008 Annual Research Report
  • [Presentation] Biological activities of Salmonella enterotoxin.2008

    • Author(s)
      Yamasaki E, Hoshi H, Seto Y, Chongsa-nguan M, Chicumpa W, G B Nair, Makino S-I, Hirayama T, Kurazono H
    • Organizer
      The 43rd Joint Conference US-Japan Cooperative Medical Science Program, Cholera Panel
    • Place of Presentation
      Fukuoka, Japan
    • Related Report
      2010 Final Research Report
  • [Presentation] 尿路由来キノロン耐性大腸菌の系統分類、保有病原因子検討2008

    • Author(s)
      高橋彰、山本新吾、石川清仁、安田満、高橋聡、門田晃一、村谷哲郎、清田浩、荒川創一、松本哲朗
    • Organizer
      第96回日本泌尿器科学会総会
    • Place of Presentation
      横浜市
    • Related Report
      2008 Annual Research Report
  • [Presentation] Biological activities of Salmonella enterotoxin2008

    • Author(s)
      Yamasaki E, Hoshi H, Seto Y, Chongsa-nguan M, Chicumpa W, GB Nair, Makino S-I, Hirayama T, Kurazono H
    • Organizer
      The 43rd Joint Conference US -Japan Cooperative Medical Science Program, Cholera Panel
    • Place of Presentation
      福岡市
    • Related Report
      2008 Annual Research Report
  • [Presentation] Helicobacter pylori VacA-induced IL-8 production in U937 cells is mediated by an increase in intracellular Ca2+, followed by activation of ATF-2, CREB and NF-kB2008

    • Author(s)
      Toshiya Hirayama, Jyunzo Hisatsune, Eiki Yamasaki, Hisao Kurazono, Kinnosuke Yahiro, and Joel Moss
    • Organizer
      The 43rd Joint Conference US-Japan Cooperative Medical Science Program, Cholera Panel
    • Place of Presentation
      福岡市
    • Related Report
      2008 Annual Research Report
  • [Remarks] ホームページ等

    • Related Report
      2010 Final Research Report

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Published: 2008-04-01   Modified: 2016-04-21  

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