Molecular biology and epidemiological analysis of Ent plasmid transmission in Enterotoxigenic Escherichia coli.
Project/Area Number |
20590459
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Bacteriology (including Mycology)
|
Research Institution | Fujita Health University |
Principal Investigator |
OCHI Sadayuki 藤田保健衛生大学, 医学部, 准教授 (80268705)
|
Project Period (FY) |
2008 – 2012
|
Project Status |
Completed (Fiscal Year 2012)
|
Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2012: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2011: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2010: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2009: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2008: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
|
Keywords | 病原細菌 / プラスミド / 下痢原性大腸菌 / 毒素原性大腸菌 / エントプラスミド / 易熱性エンテロトキシン / 病原プラスミド |
Research Abstract |
The complete nucleotide sequence was determined for an Ent plasmid (pEntH10407) in enterotoxigenic Escherichia coli H10407. Sequence analysis indicated that pEntH10407 contains three distinct major regions: (i) a pathogenicity islet containing enterotoxin genes, (ii) a region involved in plasmid replication and maintenance, and (iii) a region including tra genes that cause the self-transmissibility. This raises possibility that the H10407 strain might have been born by self-transmissibility of pEntH10407.
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Report
(7 results)
Research Products
(64 results)
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[Journal Article] Role of sphingomyelinase in infectious diseases caused by Bacillus cereus2012
Author(s)
Masataka Oda, Manabu Hashimoto, Masaya Takahashi, Yuka Ohmae, Soshi Seike, Ryoko Kato, Aoi Fujita, Hideaki Tsuge, Masahiro Nagahama, Sadayuki Ochi, Teppei Sasahara,Shunji Hayashi, Yoshikazu Hirai and Jun Sakurai
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Peer Reviewed
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[Presentation] Enteroaggregative Escherichia coli associated with a massive outbreak of gastrointestinal illness in Mandera, Kenya2012
Author(s)
Martin Bundi, Sadayuki Ochi, Gabriel Miringu, Angela Makumi, Sora Huka, Ernest Wander, Amina Galat, Victor Ager, Mwajuma Abubakar, David Mutonga, D. Langat, Hillary Limo, Z. Irura, Mohamed Karama, Takao Tsuji and Yoshio Ichinose
Organizer
2nd KEMRI Annual Scientific & Health (KASH) Conference
Place of Presentation
Nairobi、Kenya
Year and Date
2012-02-08
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