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Molecular biology and epidemiological analysis of Ent plasmid transmission in Enterotoxigenic Escherichia coli.

Research Project

Project/Area Number 20590459
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Bacteriology (including Mycology)
Research InstitutionFujita Health University

Principal Investigator

OCHI Sadayuki  藤田保健衛生大学, 医学部, 准教授 (80268705)

Project Period (FY) 2008 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2012: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2011: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2010: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2009: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2008: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywords病原細菌 / プラスミド / 下痢原性大腸菌 / 毒素原性大腸菌 / エントプラスミド / 易熱性エンテロトキシン / 病原プラスミド
Research Abstract

The complete nucleotide sequence was determined for an Ent plasmid (pEntH10407) in enterotoxigenic Escherichia coli H10407. Sequence analysis indicated that pEntH10407 contains three distinct major regions: (i) a pathogenicity islet containing enterotoxin genes, (ii) a region involved in plasmid replication and maintenance, and (iii) a region including tra genes that cause the self-transmissibility. This raises possibility that the H10407 strain might have been born by self-transmissibility of pEntH10407.

Report

(7 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report   Self-evaluation Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (64 results)

All 2012 2011 2010 2009 2008 Other

All Journal Article (23 results) (of which Peer Reviewed: 23 results) Presentation (41 results)

  • [Journal Article] Role of sphingomyelinase in infectious diseases caused by Bacillus cereus2012

    • Author(s)
      Masataka Oda, Manabu Hashimoto, Masaya Takahashi, Yuka Ohmae, Soshi Seike, Ryoko Kato, Aoi Fujita, Hideaki Tsuge, Masahiro Nagahama, Sadayuki Ochi, Teppei Sasahara,Shunji Hayashi, Yoshikazu Hirai and Jun Sakurai
    • Journal Title

      PLoS One

      Volume: 7(6)

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Role of phospholipid metabolism and G protein in the action induced by Clostridium perfringens alpha-toxin2012

    • Author(s)
      Masahiro Nagahama, Masataka Oda, Sadayuki Ochi, Keiko Kobayashi and Jun Sakurai
    • Journal Title

      J. Glycom. Lipidom

      Volume: 2 (3) Issue: 01

    • DOI

      10.4172/2153-0637.s3-001

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] P19 embryonal carcinoma cells exhibit high sensitivity to botulinum type C and D/C mosaic neurotoxins2012

    • Author(s)
      Kentaro Tsukamoto, Hideyuki Arimitsu, Sadayuki Ochi, Keiji Nakamura, Yoshikazu Tanaka, Nipawan Nuemket, Koki Taniguchi, Shunji Kozaki and Takao Tsuji
    • Journal Title

      Microbiol. Immunol

      Volume: 56(10) Issue: 10 Pages: 664-672

    • DOI

      10.1111/j.1348-0421.2012.00490.x

    • NAID

      40019437037

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Role of sphingomyelinase in infectious diseases caused by Bacillus cereus.2012

    • Author(s)
      Masataka Oda
    • Journal Title

      PLoS One

      Volume: 7 Issue: 6 Pages: e38054-e38054

    • DOI

      10.1371/journal.pone.0038054

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Recent insights into Clostridium perfringens alpha-toxin2012

    • Author(s)
      Masahiro Nagahama
    • Journal Title

      Res.Adv.in.Infect.Immun.

      Volume: 1 Pages: 1-12

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Recent insights into Clostridium perfringens alpha-toxin2011

    • Author(s)
      Masahiro Nagahama, Masataka Oda, Sadayuki Ochi, Keiko Kobayashi and Jun Sakurai
    • Journal Title

      Res. Adv. Infect. Immun

      Volume: 1 Pages: 1-10

    • URL

      http://www.trnres.com/index.htm

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Nucleotide sequence analysis of the enterotoxigenic Escherichia coli Ent plasmid2009

    • Author(s)
      Sadayuki Ochi, Tohru Shimizu, Kaori Ohtani, Yoshio Ichinose, Hideyuki Arimitsu,Kentaro Tsukamoto, MichioKato and Takao Tsuji
    • Journal Title

      DNA Res

      Volume: 16(5) Issue: 5 Pages: 299-309

    • DOI

      10.1093/dnares/dsp015

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Lincomycin-induced over- expression of mature recombinant cholera toxin B subunit and the holotoxin in Escherichia coli2009

    • Author(s)
      Hideyuki Arimitsu, Kentaro Tsukamoto, Sadayuki Ochi, Keiko Sasaki, Michio Kato, Koki Taniguchi, Keiji Oguma and Takao Tsuji
    • Journal Title

      Protein Expr. Purif

      Volume: 67(2) Issue: 2 Pages: 96-103

    • DOI

      10.1016/j.pep.2009.04.011

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Nucleotide sequence analysis of the enterotoxigenic Escherichia coli Ent plasmid.2009

    • Author(s)
      Ochi, S., et al.
    • Journal Title

      DNA Res. 16

      Pages: 299-309

    • Related Report
      2010 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] Lincomycin-induced over-expression of mature recombinant cholera toxin B subunit and the holotoxin in Escherichia coli.2009

    • Author(s)
      Arimitsu, H., Ochi, S., et al.
    • Journal Title

      Protein Expr.Purif. 67

      Pages: 96-103

    • Related Report
      2010 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] Nucleotide sequence analysis of the enterotoxigenic Escherichia coli Ent plasmid2009

    • Author(s)
      Ochi, S., et al.
    • Journal Title

      DNA Res. 16

      Pages: 299-309

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Lincomycin-induced over-expression of mature recombinant cholera toxin B subunit and the holotoxin in Escherichia coli2009

    • Author(s)
      Arimitsu, H., et al.
    • Journal Title

      Protein Expr.Purif. 67

      Pages: 96-103

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The relationship between the metabolism of sphingomyelin species and the hemolysis of sheep erythrocytes induced by Clostridium perfringens a-toxin2008

    • Author(s)
      Masataka Oda, Takayuki Matsuno, Ryouta Shiihara, Sadayuki Ochi, Rieko Yamauchi, Yuki Saito, Hiroshi Imagawa, Masahiro Nagahama, Mugio Nishizawa and Jun Sakurai
    • Journal Title

      J. Lipid Res

      Volume: 49(5) Issue: 5 Pages: 1039-1047

    • DOI

      10.1194/jlr.m700587-jlr200

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Molecular properties of each subcomponent in Clostridium botulinum type B haemagglutinin complex2008

    • Author(s)
      Hideyuki Arimitsu, Yoshihiko Sakaguchi, Jae-Chul Lee, Sadayuki Ochi, Kentaro Tsukamoto, Yumiko Yamamoto, Shaobo Ma, Takao Tsuji and Keiji Oguma
    • Journal Title

      Microb. Pathog

      Volume: 45 (2) Issue: 2 Pages: 142-149

    • DOI

      10.1016/j.micpath.2008.04.007

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Paola Neri and Hiroshi Mori. A nasal vaccine comprising B-subunit derivative of Shiga toxin 2 for cross-protection against Shiga toxin types 1 and 22008

    • Author(s)
      Takao Tsuji, Takeshi Shimizu, Keiko Sasaki, Kentaro Tsukamoto, Hideyuki Arimitsu, Sadayuki Ochi, Toshiyasu Shimizu, Koki Taniguchi, Masatoshi Noda
    • Journal Title

      Vaccine

      Volume: 26(17) Issue: 17 Pages: 2092-2099

    • DOI

      10.1016/j.vaccine.2008.02.034

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Protection of mice from Shiga toxin-2 toxemia by mucosal vaccine of Shiga toxin 2B-His with Escherichia coli enterotoxin2008

    • Author(s)
      Takao Tsuji, Takeshi Shimizu, Keiko Sasaki, Yoshiyasu Shimizu, Kentaro Tsukamoto, Hideyuki Arimitsu, Sadayuki Ochi, Satoshi Sugiyama, Koki Taniguchi Paola Neri, Hiroshi Mori
    • Journal Title

      Vaccine

      Volume: 26(4) Pages: 469-476

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] The relationship between the metabolism of sphingomyelin species and the hemolysis of sheep erythrocytes induced by Clostridium perfringens α-toxin.2008

    • Author(s)
      Oda, M., Ochi, S., et al.
    • Journal Title

      J.Lipid Res. 49

      Pages: 1039-1047

    • Related Report
      2010 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] A nasal vaccine comprising B-subunit derivative of Shiga toxin 2 for cross-protection against Shiga toxin types 1 and 2.2008

    • Author(s)
      Tsuji, T., Ochi, S., et al.
    • Journal Title

      Vaccine 26

      Pages: 2092-2099

    • Related Report
      2010 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] Protection of mice from Shiga toxin-2 toxemia by mucosal vaccine of Shiga toxin 2B-His with Escherichia coli enterotoxin.2008

    • Author(s)
      Tsuji, T., Ochi, S., et al.
    • Journal Title

      Vaccine 26

      Pages: 469-476

    • Related Report
      2010 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] Proteclion of mice from Shiaa toxin-2 toxemia by mucosal vacciue of Shigatoxin 2B-His with Escherichia coli enterotoxin.2008

    • Author(s)
      Tsuji, T., et al.
    • Journal Title

      Vaccine 26

      Pages: 469-476

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The relationship between the metabolism of sphingomyelin species and thehemolysis of sheep erythrocytes induced by Closlridium perfringens alpha-loxin.2008

    • Author(s)
      Oda, M., et al.
    • Journal Title

      J. Lipid Res. 49

      Pages: 1039-1047

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A nasal vaccine comprising B -subunit derivative of Shiga toxin 2 for cross-protection against Shiga toxin types 1 and 2.2008

    • Author(s)
      Tsuii, T., et al.
    • Journal Title

      Vaccine 26

      Pages: 2092-2099

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Role of phospholipid metabolism and G protein in the action induced by Clostridium perfringens alpha-toxin

    • Author(s)
      Masahiro Nagahama
    • Journal Title

      Jounal of Glycomics and Lipidomics

      Volume: (in press)

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Presentation] Carbohydrate structure of lincomycin activates lac promoter in Escherichia coli2012

    • Author(s)
      Hideyuki Arimitsu, Kentaro Tsukamoto,Sadayuki Ochi, Keiko Sasaki, Takao Tsuji、
    • Organizer
      The 47th Annual Joint Panel Meeting on Cholera and Other Bacterial Enteric Infections Panel: United States-Japan Cooperative Medical Science Program
    • Place of Presentation
      千葉市
    • Year and Date
      2012-12-13
    • Related Report
      2012 Final Research Report
  • [Presentation] ケニアのマンデラ東県で発生した下痢症アウトブレイクの 原因菌の疫学調査2012

    • Author(s)
      越智定幸、Martin Bundi、Sora Suka、有満秀幸、塚本健太郎、佐々木慶子、清水 利康、一瀬休生、辻孝雄
    • Organizer
      第48回日本細菌学会中部支部総会
    • Place of Presentation
      金沢市
    • Year and Date
      2012-11-09
    • Related Report
      2012 Final Research Report
  • [Presentation] ケニア・マンデラ地方下痢症のアウトブレイクに関連するEAST1遺伝子保有大腸菌2012

    • Author(s)
      越智定幸、マーチンブンディ、ソラスカ、嶺直幸、有満秀幸、塚本健太郎、佐々木慶子、清水利康、一瀬休生、辻孝雄
    • Organizer
      第85回日本細菌学会総会
    • Place of Presentation
      長崎市
    • Year and Date
      2012-03-28
    • Related Report
      2012 Final Research Report
  • [Presentation] ケニア・マンデラ地方下痢症のアウトブレイクに関連するEAST1遺伝子保有大腸菌2012

    • Author(s)
      越智定幸
    • Organizer
      第84回日本細菌学会総会
    • Place of Presentation
      長崎新聞文化ホール(招待講演)
    • Year and Date
      2012-03-28
    • Related Report
      2011 Annual Research Report
  • [Presentation] 胚性腫瘍細胞P19を用いたボツリヌス神経毒素の作用機構の解析2012

    • Author(s)
      塚本健太郎
    • Organizer
      第84回日本細菌学会総会
    • Place of Presentation
      長崎新聞文化ホール
    • Year and Date
      2012-03-28
    • Related Report
      2011 Annual Research Report
  • [Presentation] Enteroaggregative Escherichia coli associated with a massive outbreak of gastrointestinal illness in Mandera, Kenya2012

    • Author(s)
      Martin Bundi, Sadayuki Ochi, Gabriel Miringu, Angela Makumi, Sora Huka, Ernest Wander, Amina Galat, Victor Ager, Mwajuma Abubakar, David Mutonga, D. Langat, Hillary Limo, Z. Irura, Mohamed Karama, Takao Tsuji and Yoshio Ichinose
    • Organizer
      2nd KEMRI Annual Scientific & Health (KASH) Conference
    • Place of Presentation
      Nairobi、Kenya
    • Year and Date
      2012-02-08
    • Related Report
      2012 Final Research Report
  • [Presentation] Enteroaggregative Escherichia coli associated with a massive outbreak of gastrointestinal illness in Mandera, Kenya2012

    • Author(s)
      Martin Bundi
    • Organizer
      2^<nd> KEMRI Annual Scientific & Health Conference
    • Place of Presentation
      KEMRI Headquarters
    • Year and Date
      2012-02-08
    • Related Report
      2011 Annual Research Report
  • [Presentation] ケニアのマンデラ東県で発生した下痢症アウトブレイクの原因菌の疫学調査2012

    • Author(s)
      越智定幸
    • Organizer
      日本細菌学会中部支部総会
    • Place of Presentation
      金沢市、金沢大学医学部記念館
    • Related Report
      2012 Annual Research Report
  • [Presentation] Carbohydrate structure of lincomycin activates lac promoter in Escherichia coli2012

    • Author(s)
      Hideyuki Arimitsu
    • Organizer
      第47 回日米コレラ部会合同会議
    • Place of Presentation
      千葉市、千葉大学120周年記念講堂
    • Related Report
      2012 Annual Research Report
  • [Presentation] Lincomycin-induced overexpression method of mutant Shiga toxin-2 for vaccine antigen2011

    • Author(s)
      Hideyuki Arimitsu, Sadayuki Ochi, Kentaro Tsukamoto, Keiko Sasaki and Takao Tsuji
    • Organizer
      The 46th Annual Joint Panel Meeting on Cholera and Other Bacterial Enteric Infections Panel: United States-Japan Cooperative Medical Science Program
    • Place of Presentation
      Kolkata、India
    • Year and Date
      2011-12-14
    • Related Report
      2012 Final Research Report
  • [Presentation] Lincomycin-induced overexpression method of mutant Shiga toxin-2 for vaccine antigen2011

    • Author(s)
      Hideyuki Arimitsu
    • Organizer
      46th Joint Meeting and Conference of the US-Japan Panel on Cholera and Other Bacterial Enteric Infections
    • Place of Presentation
      Hyatt Regency Hotel, Kolkata
    • Year and Date
      2011-12-07
    • Related Report
      2011 Annual Research Report
  • [Presentation] 変異Shiga toxin-2トキソイドの過剰産生系の作製2011

    • Author(s)
      有満秀幸
    • Organizer
      第47回日本細菌学会中部支部総会
    • Place of Presentation
      名古屋大学シンポシオンホール
    • Year and Date
      2011-10-21
    • Related Report
      2011 Annual Research Report
  • [Presentation] Structure and activity of receptor binding domain of Clostridium botulinum D/C mosaic neurotoxin2011

    • Author(s)
      塚本健太郎
    • Organizer
      第84回日本細菌学会総会
    • Place of Presentation
      札幌コンベンションセンター
    • Year and Date
      2011-09-10
    • Related Report
      2011 Annual Research Report
  • [Presentation] Over-expression methods of shiga toxin 1, shiga toxin 2 and their mutants in Escherichia coli for evaluating toxoid vaccine2011

    • Author(s)
      有満秀幸
    • Organizer
      第84回日本細菌学会総会
    • Place of Presentation
      札幌コンベンションセンター
    • Year and Date
      2011-09-10
    • Related Report
      2011 Annual Research Report
  • [Presentation] Over-expression methods of shiga toxin 1, shiga toxin 2 and their mutants in Escherichia coli for evaluating toxoid vaccine2011

    • Author(s)
      Hideyuki Arimitsu, Kentaro Tsukamoto, Sadayuki Ochi, Keiko Sasaki, Michio Kato and Takao Tsuji
    • Organizer
      第84回日本細菌学会総会
    • Place of Presentation
      札幌市
    • Year and Date
      2011-09-07
    • Related Report
      2012 Final Research Report
  • [Presentation] Structure and activity of receptor binding domain of Clostridium botulinum D/C mosaic neurotoxin2011

    • Author(s)
      Kentaro Tsukamto, Nipawan Nuemket, Yoshikazu Tanaka, Hideyuki Arimitsu, Sadayuki Ochi, Keiji Nakamura, Shunji Kozaki, Isao Tanaka and Takao Tsuji
    • Organizer
      第84回日本細菌学会総会
    • Place of Presentation
      札幌市
    • Year and Date
      2011-09-07
    • Related Report
      2012 Final Research Report
  • [Presentation] 変異滋賀毒素を抗原としたコレラ毒素及びその変異体のアジュバント効果の比較2011

    • Author(s)
      有満秀幸
    • Organizer
      トキシンシンポジウム
    • Place of Presentation
      順天堂大学本郷キャンパス
    • Year and Date
      2011-07-07
    • Related Report
      2011 Annual Research Report
  • [Presentation] Analysis of the transfer and plasmid maintenance regions of the enterotoxigenic Escherichia coli Ent plasmid pEntH104072010

    • Author(s)
      Sadayuki Ochi, Tohru Shimizu, Kaori Ohtani, Yoshio Ichinose, Hideyuki Arimitsu, Kentaro Tsukamoto, Michio Kato, Toshiyasu Shimizu and Takao Tsuji
    • Organizer
      The 45th Annual Joint Panel Meeting on Cholera and Other Bacterial Enteric Infections Panel: United States-Japan Cooperative Medical Science Program
    • Place of Presentation
      京都市
    • Year and Date
      2010-12-07
    • Related Report
      2012 Final Research Report
  • [Presentation] Analysis of the transfer and plasmid maintenance regions of the enterotoxigenic Escherichia coli Ent plasmid pEntH104072010

    • Author(s)
      Sadayuki Ochi
    • Organizer
      The 45th Annual Joint Panel Meeting on Cholera and Other Bacterial Enteric Infections Panel
    • Place of Presentation
      Kyoto
    • Year and Date
      2010-12-07
    • Related Report
      2010 Self-evaluation Report
  • [Presentation] Analysis of the transfer and plasmid maintenance regions of the enterotoxigenic Escherichia coli Ent plasmid pEntH104072010

    • Author(s)
      Sadayuki Ochi
    • Organizer
      45th US-Japan Cholera and other Bacterial Enteric Infections Joint Panel Meeting
    • Place of Presentation
      Inamori Foundation Memorial Hall
    • Year and Date
      2010-12-07
    • Related Report
      2010 Annual Research Report
  • [Presentation] ボツリヌスC型及びDCモザイク神経毒素は異なるガングリオシドを介して細胞内に侵入する2010

    • Author(s)
      西脇啓太
    • Organizer
      日本細菌学会中部支部
    • Place of Presentation
      日本歯科大学新潟生命歯学部講堂
    • Year and Date
      2010-10-23
    • Related Report
      2010 Annual Research Report
  • [Presentation] コレラ毒素によるマウス脾臓細胞のCREB活性化シグナル伝達経路の解析2010

    • Author(s)
      有満秀幸
    • Organizer
      トキシンシンポジウム
    • Place of Presentation
      長浜ロイヤルホテル
    • Year and Date
      2010-07-16
    • Related Report
      2010 Annual Research Report
  • [Presentation] 毒素原性大腸菌H10407株Entプラスミドの機能領域の配列解析2010

    • Author(s)
      越智定幸
    • Organizer
      第57回トキシンシンポジウム
    • Place of Presentation
      滋賀県長浜市
    • Year and Date
      2010-07-15
    • Related Report
      2010 Self-evaluation Report
  • [Presentation] 毒素原性大腸菌H10407株Entプラスミドの機能領域の配列解析2010

    • Author(s)
      越智定幸
    • Organizer
      トキシンシンポジウム
    • Place of Presentation
      長浜ロイヤルホテル
    • Year and Date
      2010-07-15
    • Related Report
      2010 Annual Research Report
  • [Presentation] ボツリヌス神経毒素受容体結合領域の結晶構造と細胞内侵入機構の解析2010

    • Author(s)
      塚本健太郎
    • Organizer
      トキシンシンポジウム
    • Place of Presentation
      長浜ロイヤルホテル
    • Year and Date
      2010-07-15
    • Related Report
      2010 Annual Research Report
  • [Presentation] Human naive antibodies against Shiga toxins isolated from a phage-display library2010

    • Author(s)
      Paola Neri
    • Organizer
      トキシンシンポジウム
    • Place of Presentation
      長浜ロイヤルホテル
    • Year and Date
      2010-07-15
    • Related Report
      2010 Annual Research Report
  • [Presentation] 毒素原性大腸菌H10407株Entプラスミドの機能領域の配列解析2010

    • Author(s)
      越智定幸、清水徹、大谷郁、有満秀幸、塚本健太郎、佐々木慶子、加藤道夫、一瀬休生、辻孝雄
    • Organizer
      第57回トキシンシンポジウム
    • Place of Presentation
      長浜市
    • Year and Date
      2010-07-14
    • Related Report
      2012 Final Research Report
  • [Presentation] 毒素原性大腸菌H10407株Entプラスミドの機能領域配列解析2010

    • Author(s)
      越智定幸
    • Organizer
      第83回日本細菌学会総会
    • Place of Presentation
      神奈川県横浜市
    • Year and Date
      2010-03-28
    • Related Report
      2010 Self-evaluation Report
  • [Presentation] 毒素原性大腸菌H10407株Entプラスミドの機能領域解析2010

    • Author(s)
      越智定幸
    • Organizer
      日本細菌学会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2010-03-28
    • Related Report
      2009 Annual Research Report
  • [Presentation] 毒素原性大腸菌H10407株Entプラスミドの接合伝達領域2009

    • Author(s)
      越智定幸、有満秀幸、塚本健太郎、大谷郁、Neri Paola、佐々木慶子、加藤道夫、一瀬休生、清水徹、辻孝雄
    • Organizer
      第46回日本細菌学会中部支部総会
    • Place of Presentation
      名古屋市
    • Year and Date
      2009-12-23
    • Related Report
      2012 Final Research Report
  • [Presentation] 毒素原性大腸菌H10407株Entプラスミドの接合伝達領域2009

    • Author(s)
      越智定幸
    • Organizer
      第46回日本細菌学会中部支部総会
    • Place of Presentation
      愛知県名古屋市
    • Year and Date
      2009-10-24
    • Related Report
      2010 Self-evaluation Report
  • [Presentation] EC細胞を用いたボツリヌス神経毒素重鎖C末端領域の機能解析2009

    • Author(s)
      塚本健太郎
    • Organizer
      日本細菌学会中部支部
    • Place of Presentation
      名城大学薬学部ライフサイエンスホール
    • Year and Date
      2009-10-24
    • Related Report
      2009 Annual Research Report
  • [Presentation] 毒素原性大腸菌H10407株Entプラスミドの接合伝達領域2009

    • Author(s)
      越智定幸
    • Organizer
      日本細菌学会中部支部
    • Place of Presentation
      名城大学薬学部ライフサイエンスホール
    • Year and Date
      2009-10-23
    • Related Report
      2009 Annual Research Report
  • [Presentation] Construction of over-expression and purification system of cholera toxin and its mutants in Escherichia coli2009

    • Author(s)
      Arimitsu Hideyuki
    • Organizer
      44th US-Japan Cholera and other Bacterial Enteric Infections Joint Panel Meeting
    • Place of Presentation
      Hilton San Diego Mission Valley
    • Year and Date
      2009-10-13
    • Related Report
      2009 Annual Research Report
  • [Presentation] ボツリヌス神経毒素重鎖C末端領域の脂質受容体に対する結合活性2009

    • Author(s)
      塚本健太郎
    • Organizer
      トキシンシンポジウム
    • Place of Presentation
      アルモニーテラッセ
    • Year and Date
      2009-08-26
    • Related Report
      2009 Annual Research Report
  • [Presentation] 毒素原性大腸菌H10407株Entプラスミドの配列解析2009

    • Author(s)
      越智定幸
    • Organizer
      第82回日本細菌学会総会
    • Place of Presentation
      愛知県名古屋市
    • Year and Date
      2009-03-12
    • Related Report
      2010 Self-evaluation Report
  • [Presentation] 毒素原性大腸菌H10407株Entプラスミドの配列解析2009

    • Author(s)
      越智定幸
    • Organizer
      日本細菌学会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2009-03-12
    • Related Report
      2008 Annual Research Report
  • [Presentation] Construction of lincomycin-induced expression system of cholera toxin B subunit in Escherichia coli2008

    • Author(s)
      Hideyuki Arimitsu, Kentaro Tsukamoto, Sadayuki Ochi, Keiko Sasaki, and Takao Tsuji
    • Organizer
      The 43th Joint Meeting of the US-Japan Cholera and other Bacterial Enteric Infections Panel
    • Place of Presentation
      福岡市
    • Year and Date
      2008-11-18
    • Related Report
      2012 Final Research Report
  • [Presentation] 毒素原性大腸菌H10407株Entプラスミドの塩基配列解析2008

    • Author(s)
      越智定幸、有満秀幸、塚本健太郎、大谷郁、佐々木慶子、加藤道夫、清水徹、辻孝雄
    • Organizer
      第45回日本細菌学会中部支部総会
    • Place of Presentation
      金沢市
    • Year and Date
      2008-10-17
    • Related Report
      2012 Final Research Report
  • [Presentation] 毒素原性大腸菌H10407株Entプラスミドの全塩基配列決定と解析2008

    • Author(s)
      越智定幸、有満秀幸、塚本健太郎、大谷郁、佐々木慶子、清水徹、辻孝雄
    • Organizer
      第20回微生物シンポジウム
    • Place of Presentation
      岐阜市
    • Year and Date
      2008-09-03
    • Related Report
      2012 Final Research Report
  • [Presentation]2008

    • Author(s)
      越智定幸、有満秀幸、塚本健太郎、大谷郁、佐々木慶子、加藤道夫、清水徹、辻孝雄
    • Organizer
      第55回毒素シンポジウム
    • Place of Presentation
      南都留郡
    • Year and Date
      2008-07-03
    • Related Report
      2012 Final Research Report

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Published: 2008-04-01   Modified: 2019-07-29  

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