| Project/Area Number |
20590549
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Applied pharmacology
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| Research Institution | St.Marianna University School of Medicine |
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Principal Investigator |
KOBAYASHI Shinichi St.Marianna University School of Medicine, 医学部, 教授 (20129836)
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| Co-Investigator(Kenkyū-buntansha) |
KUMAI Toshio 聖マリアンナ医科大学, 医学(系)研究科(研究院), 教授 (40139671)
TANAKA Masami 聖マリアンナ医科大学, 医学(系)研究科(研究院), 准教授 (00171801)
NAKANO Hiroshi 聖マリアンナ医科大学, 医学部, 准教授 (10241035)
TAKENOSHITA Sachiko 聖マリアンナ医科大学, 医学部, 助教 (10386948)
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| Project Period (FY) |
2008 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2010: ¥260,000 (Direct Cost: ¥200,000、Indirect Cost: ¥60,000)
Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2008: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
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| Keywords | テーラーメード医療 / 抗癌薬 / 遺伝子多型 / 薬物代謝酵素 / トランスポーター / DPD / ハプロタイプ |
|---|
| Research Abstract |
We were constructed the genotyping system which was efficiently measurement of genotype for CYP and transporter. The system which was able to analyze a lot of multi genotypes with accuracy in a short time was constructed for CYP2D6 and CYP3A4. During this experimental period, new sample was collected and done genotyping. Surgeon was request more simple information of the feedback system of multi genotype.
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