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Sleep habit, insulin resistance and metabolic syndrome for shift workers

Research Project

Project/Area Number 20590616
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Hygiene
Research InstitutionNippon Medical School

Principal Investigator

KAWADA Tomoyuki  日本医科大学, 大学院・医学研究科, 教授 (00224791)

Co-Investigator(Kenkyū-buntansha) INAGAKI Hirofumi  日本医科大学, 医学部, 講師 (50213111)
WAKAYAMA Yoko  日本医科大学, 医学部, 講師 (40104062)
LI Qing  日本医科大学, 医学部, 講師 (50250048)
OTSUKA Toshiaki  日本医科大学, 医学部, 講師 (80339374)
LI Ying ji  日本医科大学, 医学部, 講師 (60350039)
KATSUMATA Masao  日本医科大学, 医学部, 助教 (80169482)
Project Period (FY) 2008 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2011: ¥260,000 (Direct Cost: ¥200,000、Indirect Cost: ¥60,000)
Fiscal Year 2010: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2009: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2008: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Keywords産業衛生 / 交替制勤務 / 生活習慣 / 睡眠 / インスリン抵抗性 / メタボリック症候群 / 自覚的睡眠感 / アメニティ / QOL
Research Abstract

I conducted health survey to know factors significantly associated with metabolic syndrome(MetS). The target subjects are 3, 054 occupational workers aged 34-64 years without any of the following problems ; insomnia, having medication with diabetes mellitus, hypertension, dyslipidemia, cardio-vascular disease, hyperuricemia. By logistic regression analysis, serum insulin was the strongest predictor of Mets, followed by liver enzymes, uric acid, and non-smoking. Shift work and sleeping time were not selected as significant contributors for MetS.

Report

(6 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report   Self-evaluation Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (39 results)

All 2012 2011 2010 2009 Other

All Journal Article (39 results) (of which Peer Reviewed: 38 results)

  • [Journal Article] Effect of metabolic components on the incidence of cerebrovascular/cardiovascular disease among male workers in Japan : 3-year follow-up study2012

    • Author(s)
      Kawada T.
    • Journal Title

      J Clin Hypertens

      Volume: 14(1) Issue: 1 Pages: 67-67

    • DOI

      10.1111/j.1751-7176.2011.00561.x

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Predictors of the development of metabolic syndrome in male workers : a 3-year follow-up study2012

    • Author(s)
      Kawada T.
    • Journal Title

      J Occup Environ Med

      Volume: 54(3) Issue: 3 Pages: 292-295

    • DOI

      10.1097/jom.0b013e3182492070

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Relationship between several markers and presence of metabolic syndrome or components of the metabolic components in Japanese workers2012

    • Author(s)
      Kawada T.
    • Journal Title

      J Occup Environ Med

      Volume: (in press) Issue: 8 Pages: 984-988

    • DOI

      10.1097/jom.0b013e31825335ae

    • Related Report
      2011 Final Research Report
  • [Journal Article] Monitoring of the sleep patterns of shift workers in the automotive industry2011

    • Author(s)
      Kawada T, Shimizu T, Kuratomi Y, Suto S, Kanai T, Nishime A, Nakano N.
    • Journal Title

      Work

      Volume: 38(2) Issue: 2 Pages: 163-167

    • DOI

      10.3233/wor-2011-1118

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Optimal cut-off levels of body mass index and waist circumference to predict each component of metabolic syndrome(MetS) and the number of MetS component2011

    • Author(s)
      Kawada T, Otsuka T, Inagaki H, Wakayama Y, Li Q, Li YJ, Katsumata M.
    • Journal Title

      Diabetes Metab Syndr

      Volume: 5(1) Issue: 1 Pages: 25-28

    • DOI

      10.1016/j.dsx.2010.05.012

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] The metabolic syndrome, smoking, inflammatory markers and obesity2011

    • Author(s)
      Kawada T, Otsuka T, Endo T, Kon Y
    • Journal Title

      Int J Cardiol

      Volume: 151 Issue: 3 Pages: 367-368

    • DOI

      10.1016/j.ijcard.2011.06.095

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Monitoring of the sleep patterns of shift workers in the automotive industry.2011

    • Author(s)
      Kawada T, Shimizu T, Kuratomi Y, Suto S, Kanai T, Nishime A, Nakano N.
    • Journal Title

      Work

      Volume: 38(2) Pages: 163-167

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Insulin resistance, as expressed by HOMA-R, is strongly determined by waist circumference or body mass index among Japanese working men2010

    • Author(s)
      Kawada T, Otsuka T, Inagaki H, Wakayama Y, Li Q, Li YJ, Katsumata M.
    • Journal Title

      Obes Res & Clin Practice

      Volume: 4 Issue: 1 Pages: e9-e14

    • DOI

      10.1016/j.orcp.2009.07.001

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] HOMA-R, an indicator of insulin resistance, is strongly related to serum insulin : practical data presentation and its mathematical basis2010

    • Author(s)
      Kawada T.
    • Journal Title

      Metabolism

      Volume: 59(7) Pages: 1044-1046

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Serum insulin is significantly related to components of the metabolic syndrome in Japanese working men2010

    • Author(s)
      Kawada T, Inagaki H, Wakayama Y, Li Q, Katsumata M.
    • Journal Title

      J Clin Hypertens

      Volume: 12(4) Issue: 4 Pages: 309-314

    • DOI

      10.1016/j.dsx.2010.12.005

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Association of smoking status, insulin resistance, body mass index, and metabolic syndrome in workers : a one-year follow-up study2010

    • Author(s)
      Kawada T, Otsuka T, Inagaki H, Wakayama Y, Li Q, Li YJ, Katsumata M.
    • Journal Title

      Obes Res & Clin Practice

      Volume: 4 Issue: 3 Pages: e163-e169

    • DOI

      10.1016/j.orcp.2009.12.004

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] A cross-sectional study on the shift work and metabolic syndrome in Japanese male workers2010

    • Author(s)
      Kawada T, Otsuka T, Inagaki H, Wakayama Y, Katsumata M, Li Q, Li YJ.
    • Journal Title

      The Aging Male

      Volume: 13(3) Pages: 174-178

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Increasing in the prevalence of metabolic syndrome among workers according to age2010

    • Author(s)
      Kawada T, Otsuka T, Inagaki H, Wakayama Y, Li Q, Li YJ, Katsumata M.
    • Journal Title

      The aging Male

      Volume: 13(3) Issue: 3 Pages: 184-187

    • DOI

      10.3109/13685531003586983

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Association of hematological parameters and uric acid with clustered components of metabolic syndrome among Japanese male workers2010

    • Author(s)
      Kawada T, Otsuka T, Inagaki H, Wakayama Y, Katsumata M, Li Q, Li YJ.
    • Journal Title

      Diabetes Metab Syndr

      Volume: 4(3) Issue: 3 Pages: 165-167

    • DOI

      10.1016/j.dsx.2010.05.016

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Framingham Hypertension Risk Score : the prevalence estimation of hypertension after one year in the population2010

    • Author(s)
      Kawada T, Otsuka T.
    • Journal Title

      J Clin Hypertension

      Volume: 12(10) Issue: 10 Pages: 814-815

    • DOI

      10.1111/j.1751-7176.2010.00345.x

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] A cross-sectional study on lifestyles and the metabolic syndrome(MetS) components mainly targeting glucose metabolism in Japanese working men2010

    • Author(s)
      Kawada T, Otsuka T, Inagaki H, Wakayama Y, Li Q, Li YJ, Katsumata M.
    • Journal Title

      Diabetes Metab Syndr

      Volume: 4(4) Issue: 4 Pages: 230-233

    • DOI

      10.1016/j.dsx.2010.05.015

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Insulin resistance, as expressed by HOMA-R, is strongly determined by waist circumference or body mass index among Japanese working men.2010

    • Author(s)
      Kawada T, Otsuka T, Inagaki H, Wakayama Y, Li Q, Li YJ, Katsumata M.
    • Journal Title

      Obes Res Clin Pract 4(1)

    • Related Report
      2010 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] Serum insulin is significantly related to components of the metabolic syndrome in Japanese working men.2010

    • Author(s)
      Kawada T, Inagaki H, Wakayama Y, Li Q, Katsumata M.
    • Journal Title

      J Clin Hypertens 12(4)

      Pages: 309-314

    • Related Report
      2010 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] Preliminary report : homeostasis model assessment of insulin resistance, an indicator of insulin resistance, is strongly related to serum insulin : practical data presentation and the mathematical basis.2010

    • Author(s)
      Kawada T.
    • Journal Title

      Metabolism 59(7)

      Pages: 1044-1046

    • Related Report
      2010 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] Association of smoking status, insulin resistance, body mass index, and metabolic syndrome in workers : a one-year follow-up study.2010

    • Author(s)
      Kawada T, Otsuka T, Inagaki H, Wakayama Y, Li Q, Li YJ, Katsumata M.
    • Journal Title

      Obes Res Clin Pract 4(3)

    • Related Report
      2010 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] A cross-sectional study on the shift work and metabolic syndrome in Japanese male workers.2010

    • Author(s)
      Kawada T, Otsuka T, Inagaki H, Wakayama Y, Katsumata M, Li Q, Li YJ.
    • Journal Title

      The Aging Male 13(3)

      Pages: 174-178

    • Related Report
      2010 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] Increasing in the prevalence of metabolic syndrome among workers according to age.2010

    • Author(s)
      Kawada T, Otsuka T, Inagaki H, Wakayama Y, Li Q, Li YJ, Katsumata M.
    • Journal Title

      The Aging Male 13(3)

      Pages: 184-187

    • Related Report
      2010 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] Association of hematological parameters and uric acid with clustered components of metabolic syndrome among Japanese male workers.2010

    • Author(s)
      Kawada T, Otsuka T, Inagaki H, Wakayama Y, Katsumata M, Li Q, Li YJ.
    • Journal Title

      Diabetes Metab Syndr 4(3)

      Pages: 165-167

    • Related Report
      2010 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] A cross-sectional study on lifestyles and the metabolic syndrome (MetS) components mainly targeting glucose metabolism in Japanese working men.2010

    • Author(s)
      Kawada T, Otsuka T, Inagaki H, Wakayama Y, Li Q, Li YJ, Katsumata M.
    • Journal Title

      Diabetes Metab Syndr 4(4)

      Pages: 230-233

    • Related Report
      2010 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] Monitoring of the sleep patterns of shift workers in the automotive industry.2010

    • Author(s)
      Kawada T, Shimizu T, Kuratomi Y, Suto S, Kanai T, Nishime A, Nakano N.
    • Journal Title

      Work 38(2)

      Pages: 163-167

    • Related Report
      2010 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] Insulin resistance, as expressed by HOMA-R, is strongly determined by waist circumference or body mass index among Japanese working men.2010

    • Author(s)
      Kawada T, Otsuka T, Inagaki H, Wakayama Y, Li Q, Li YJ, Katsumata M.
    • Journal Title

      Obes Res & Clin Practice

      Volume: 4(1)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Serum insulin is significantly related to components of the metabolic syndrome in Japanese working men.2010

    • Author(s)
      Kawada T, Inagaki H, Wakayama Y, Li Q, Katsumata M.
    • Journal Title

      J Clin Hypertens

      Volume: 12(4) Pages: 309-314

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Preliminary report : homeostasis model assessment of insulin resistance, an indicator of insulin resistance, is strongly related to serum insulin : practical data presentation and the mathematical basis.2010

    • Author(s)
      Kawada T.
    • Journal Title

      Metabolism

      Volume: 59(7) Pages: 1044-1046

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Association of smoking status, insulin resistance, body mass index, and metabolic syndrome in workers : a one-year follow-up study.2010

    • Author(s)
      Kawada T, Otsuka T, Inagaki H, Wakayama Y, Li Q, Li YJ, Katsumata M.
    • Journal Title

      Obes Res & Clin Practice

      Volume: 4(3)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A cross-sectional study on the shift work and metabolic syndrome in Japanese male workers.2010

    • Author(s)
      Kawada T, Otsuka T, Inagaki H, Wakayama Y, Katsumata M, Li Q, Li YJ.
    • Journal Title

      The Aging Male

      Volume: 13(3) Pages: 174-178

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Increasing in the prevalence of metabolic syndrome among workers according to age.2010

    • Author(s)
      Kawada T, Otsuka T, Inagaki H, Wakayama Y, Li Q, Li YJ, Katsumata M.
    • Journal Title

      The Aging Male

      Volume: 13(3) Pages: 184-187

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Association of hematological parameters and uric acid with clustered components of metabolic syndrome among Japanese male workers.2010

    • Author(s)
      Kawada T, Otsuka T, Inagaki H, Wakayama Y, Katsumata M, Li Q, Li YJ.
    • Journal Title

      Diabetes Metab Syndr

      Volume: 4(3) Pages: 165-167

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A cross-sectional study on lifestyles and the metabolic syndrome (MetS) components mainly targeting glucose metabolism in Japanese working men.2010

    • Author(s)
      Kawada T, Otsuka T, Inagaki H, Wakayama Y, Li Q, Li YJ, Katsumata M.
    • Journal Title

      Diabetes Metab Syndr

      Volume: 4(4) Pages: 230-233

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Relationship between Two Indicators of Coronary Risk Estimated by the Framingham Risk Score and the Number of Metabolic Syndrome Components in Japanese Manufacturing Male Workers2009

    • Author(s)
      Kawada T, Otsuka T, Inagaki H, Wakayama Y, Li Q, Katsumata M.
    • Journal Title

      Met Syndr Relat Disord

      Volume: 7(5) Pages: 435-440

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Relationship between two indicators of coronary risk estimated by the Framingham Risk Score and the number of metabolic syndrome components in Japanese manufacturing male workers.2009

    • Author(s)
      Kawada T, Otsuka T, Inagaki H, Wakayama Y, Li Q, Katsumata M.
    • Journal Title

      Met Syndr Relat Disord 7(5)

      Pages: 435-440

    • Related Report
      2010 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] Anthropometric obesity indices and metabolic syndrome in Japanese working men.2009

    • Author(s)
      Kawada T, Kuratomi Y, KanaiT, Suto S, Nihsime A, Koizumi M, Nakano N.
    • Journal Title

      Work 34(1)

      Pages: 89-94

    • Related Report
      2010 Self-evaluation Report 2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Relationship between Two Indicators of Coronary Risk Estimated by the Framingham Risk Score and the number of Metabolic Syndrome Components in Japanese Manufacturing Male Workers.2009

    • Author(s)
      Kawada T, Otsuka T, Inagaki H, Wakayama Y, Li Q, Katsumata M.
    • Journal Title

      Met Syndr Relat Disord 7(5)

      Pages: 435-440

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Optimal cut-off levels of body mass index and waist circumference to predict each component of metabolic syndrome (MetS) and the number of MetS component.

    • Author(s)
      Kawada T, Otsuka T, Inagaki H, Wakayama Y, Li Q, Li YJ, Katsumata M.
    • Journal Title

      Diabetes Metab Syndr in press)

    • Related Report
      2010 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] Serum insulin is significantly related to components of the metabolic syndrome in Japanese working women.

    • Author(s)
      Kawada T, Otsuka T, Inagaki H, Wakayama Y, Li Q, Li YJ, Katsumata M.
    • Journal Title

      Diabetes Metab Syndr in press

    • Related Report
      2010 Self-evaluation Report
    • Peer Reviewed

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Published: 2008-04-01   Modified: 2016-04-21  

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