Mortality risk from lung cancer among residents living near asbestos product plants

• Project/Area Number: 20590625
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Hygiene
• Research Institution: Osaka Prefectural Institute of Public Health
• Principal Investigator: KUMAGAI Shinji Osaka Prefectural Institute of Public Health, 産業保健学部, 准教授 (50250329)
• Co-Investigator(Kenkyū-buntansha): KURUMATANI Norio 奈良県立医科大学, 医学部, 教授 (10124877)
• Project Period (FY): 2008 – 2010
• Project Status: Completed (Fiscal Year 2010)
• Budget Amount: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000); Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000); Fiscal Year 2009: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000); Fiscal Year 2008: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
• Keywords: 石綿 / 近隣曝露 / 肺がん / 周辺住民 / 標準化死亡比 / 肺癌

Research Abstract

We investigated whether individuals exposed to asbestos by living near asbestos-manufacturing plants experienced increased asbestos related disease mortality in three areas. First cohort study showed that lung cancer mortality was significantly increased among the highest exposure group of 502 households living near a plant using annual several thousand tones of amosite and chrysotile from 1942 to 1991, which suggests that neighborhood asbestos exposure can cause lung cancer. Second cohort study showed that asbestos related disease mortalities were not increased among all exposure groups of 449 households living near a plant using annual 500 tones of chrysotile from 1914 to 2001. Difference between the two findings may be caused by difference in amount and type of used asbestos. Third cohort study showed that mesothelioma mortality was increased among men of 52 households living near a plant using annual 3500 tones of chrysotile from 1954 to 1995 and annual 4700 tones of crocidolite from 1957 to 1975. This finding suggests that neighborhood asbestos exposure can cause mesothelioma.

Research Products

• [Journal Article] Increased risk of lung cancer mortality among residents near an asbestos product manufacturing plant (2010)
  • Author(s): Shinji Kumagai, Norio Kurumatani, Toshihide Tsuda, Takashi Yorifuji, Etsuji Suzuki
  • Journal Title: International Journal of Occupational and Environmental Health Vol.16 Pages: 268-278
  • Peer Reviewed
• [Journal Article] Increased Risk of Lung Cancer Mortality among Residents near an Asbestos Product Manufacturing Plant (2010)
  • Author(s): Kumagai S, Kurumatani N, Tsuda T, Yorifuji T, Suzuki E
  • Journal Title: Journal of Occupational and Environmental Health Volume: 16 Pages: 268-278
  • Peer Reviewed
• [Journal Article] Asbestos fiber concentration in the area surrounding a former asbestos cement plant and excess mesothelioma deaths in residents (2009)
  • Author(s): Shinji Kumagai, Norio Kurumatani
  • Journal Title: American Journal of Industrial Medicine Vol.52 Pages: 790-798
  • Peer Reviewed
• [Journal Article] Asbestos Fiber Concentration in the Area Surrounding a Former Asbestos Cement Plant and Excess Mesothelioma Deaths in Residents (2009)
  • Author(s): Shinji Kumagai, Norio Kurumatani
  • Journal Title: American Journal of Industrial Medicine 52 Pages: 790-798
  • Peer Reviewed
• [Presentation] Increased risk of lung cancer mortality among residents who had lived near an asbestos product manufacturing plant (2010)
  • Author(s): Shinji Kumagai, Norio Kurumatani, Toshihide Tsuda, Takashi Yorifuji, Etsuji Suzuki
  • Organizer: Joint Conference of International Society of Exposure Science & International Society for Environmental Epidemiology
  • Place of Presentation: 韓国ソウル
  • Year and Date: 2010-08-29
• [Presentation] Increased risk of lung cancer mortality among residents who had lived near an asbestos product manufacturing plant (2010)
  • Author(s): Kumagai S, Kurumatani N, Tsuda T, Yorifuji T, Suzuki E
  • Organizer: 2010 Joint Conference of International Society of Exposure Science & International Society for Environmental Epidemiology
  • Place of Presentation: 韓国、ソウル(Coex convention center)
  • Year and Date: 2010-08-29
• [Presentation] ニチアス羽島工場周辺住民における肺がんに関する疫学調査 (2009)
  • Author(s): 熊谷信二,津田敏秀,頼藤貴志、鈴木越治
  • Organizer: 石綿中皮腫研究会
  • Place of Presentation: 岐阜
  • Year and Date: 2009-10-03
• [Presentation] ニチアス羽島工場の周辺住民における肺がんによる過剰死亡 (2009)
  • Author(s): 熊谷信二,津田敏秀,頼藤貴志、鈴木越治
  • Organizer: 第82回日本産業衛生学会
  • Place of Presentation: 北九州
  • Year and Date: 2009-05-22