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Association between dietary intake and serum composition of n-3 poly unsaturated fatty acids, and it’s influence on gender difference in atherosclerosis

Research Project

Project/Area Number 20590643
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Public health/Health science
Research InstitutionShiga University of Medical Science

Principal Investigator

OKUDA Nagako  滋賀医科大学, 生活習慣病予防センター, 客員助教 (80452233)

Co-Investigator(Kenkyū-buntansha) UESHIMA Hirotsugu  滋賀医科大学, 医学部, 特任教授 (70144483)
喜多 義邦  滋賀医科大学, 医学部, 助教 (80161462)
Co-Investigator(Renkei-kenkyūsha) KITA Yoshikuni  滋賀医科大学, 医学部, 助教 (30147524)
Project Period (FY) 2008 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2011: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2010: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2009: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2008: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Keywords保健栄養 / 循環器疾患 / 脂質代謝 / 動脈硬化 / 性差 / n-3系長鎖多価不飽和脂肪酸 / 栄養
Research Abstract

Serum fatty acids compositions were measured to examine effect of gender difference in associations between dietary fatty acids intakes and serum lipids using blood samples of men and women living in Japan and Hawaii, obtained from international cooperative nutrition epidemiology study (INTERMAP). Possibility was indicated that being women, or under influence of female hormone, might be associated with less elevation of serum marine n-3 PUFA (i.e. EPA, DHA).

Report

(6 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report   Self-evaluation Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (36 results)

All 2012 2011 2010 2009 2008 Other

All Journal Article (22 results) (of which Peer Reviewed: 16 results) Presentation (14 results)

  • [Journal Article] INTERLIPID Research Group. Relation of dietary and lifestyle traits to difference in serum leptin of Japanese in Japan and Hawaii: the INTERLIPID study2012

    • Author(s)
      Nakamura Y, Ueshima H, Okuda N, Miura K, Kita Y, Okamura T, Turin TC, Okayama A, Rodriguez B, Curb JD, Stamler J
    • Journal Title

      Nutr Metab Cardiovasc Dis

      Volume: 22(1) Pages: 14-22

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Relationship between Dietary and Other Lifestyle Habits and Cardiometabolic Risk Factors in Men2011

    • Author(s)
      Katano S, Nakamura Y, Okuda N, Murakami Y, Chiba N, Yoshita K, Tanaka T, Tamaki J, Takebayashi T, Okayama A, Miura K, Okamura T, Ueshima H
    • Journal Title

      Diabetol Metab Syndr

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Relation of dietary and lifestyle traits to difference in serum leptin of Japanese in Japan and Hawaii : the INTERLIPID study2011

    • Author(s)
      Nakamura Y, Ueshima H, Okuda N, et al
    • Journal Title

      Nutr Metab Cardiovasc Dis.

      Volume: 22 Issue: 1 Pages: 14-22

    • DOI

      10.1186/1758-5996-3-30

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 岩手県矢巾町における健康支援プログラムの長期効果2011

    • Author(s)
      高橋ヤエ、岡山明、奥田奈賀子, 他
    • Journal Title

      日本循環器病予防学会誌

      Volume: 46 Pages: 243-251

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] ナトリウム・カリウム摂取と循環器疾患2011

    • Author(s)
      奥田奈賀子、岡山明
    • Journal Title

      循環器内科

      Volume: 70 Pages: 564-555

    • Related Report
      2011 Annual Research Report
  • [Journal Article] NIPPON DATA80/90 Research Group. Fatty acids intakes and serum lipid profiles: NIPPON DATA90 and the national nutrition monitoring2010

    • Author(s)
      Nakamura Y, Okuda N, Turin TC, Fujiyoshi A, Okamura T, Hayakawa T, Yoshita K, Miura K, Ueshima H
    • Journal Title

      J Epidemiol

      Volume: 20 Suppl 3

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Relationship of the polyunsaturated to saturated fatty acid ratio to cardiovascular risk factors and metabolic syndrome in Japanese: the INTERLIPID study2010

    • Author(s)
      Guo Z, Miura K, Turin TC, Hozawa A, Okuda N, Okamura T, Saitoh S, Sakata K, Nakagawa H, Okayama A, Yoshita K, Kadowaki T, Choudhury SR, Nakamura Y, Rodriguez BL, Curb DJ, Elliott P, Stamler J, Ueshima H
    • Journal Title

      J Atheroscler Thromb

      Volume: 17(8) Pages: 777-784

    • NAID

      130004845328

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Dietary sources of sodium in China, Japan, the United Kingdom, and the United States, women and men aged 40 to 59 years : the INTERMAP study.2010

    • Author(s)
      Anderson CA, Appel LJ, Okuda N, 他11名
    • Journal Title

      J Am Diet Assoc 110(5)

      Pages: 736-45

    • Related Report
      2010 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] Integration of data from NIPPON DATA80/90 and National Nutrition Survey in Japan : for cohort studies of representative Japanese on Nutrition.2010

    • Author(s)
      Okuda N, 他11名
    • Journal Title

      J Epidemiol. 20(S3)

    • NAID

      10026597259

    • Related Report
      2010 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] Dietary sources of sodium in China, Japan, the United Kingdom, and the United States, women and men aged 40 to 59 years : the INTERMAP study2010

    • Author(s)
      Anderson CA, Appel LJ, Okuda N, et al.
    • Journal Title

      J Am Diet Assoc.

      Volume: 110(5) Pages: 736-45

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Relation of dietary and lifestyle traits to difference in serum leptin of Japanese in Japan and Hawaii : The INTERLIPID study2010

    • Author(s)
      Nakamura Y, Ueshima H, Okuda N, et al.
    • Journal Title

      Nutr Metab Cardiovasc Dis.

      Volume: (In press)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Integration of data from NIPPON DATA80/90 and National Nutrition Survey in Japan : for cohort studies of representative Japanese on nutrition2010

    • Author(s)
      奥田奈賀子
    • Journal Title

      J Epidemiol 20 Suppl 3

    • NAID

      10026597259

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The INTERLIPID Study2009

    • Author(s)
      奥田奈賀子
    • Journal Title

      血栓と循環

      Volume: 17(2) Pages: 215-217

    • Related Report
      2011 Final Research Report
  • [Journal Article] 内臓脂肪減少を目的とした軽負担の保健指導が男性工場従業員の食習慣に及ぼす変化2009

    • Author(s)
      奥田奈賀子, 他12名
    • Journal Title

      日循予防誌 44

      Pages: 10-21

    • NAID

      10029554788

    • Related Report
      2010 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] 内臓脂肪減少を目的とした軽負担の保健指導が男性工場従業員の食習慣に及ぼす変化2009

    • Author(s)
      奥田奈賀子
    • Journal Title

      日循予防誌 44

      Pages: 10-21

    • NAID

      10029554788

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] INTERLIPID Research Group. Relation of dietary and other lifestyle traits to difference in serum adiponectin concentration of Japanese in Japan and Hawaii: the INTERLIPID Study2008

    • Author(s)
      Nakamura Y, Ueshima H, Okuda N, Higashiyama A, Kita Y, Kadowaki T, Okamura T, Murakami Y, Okayama A, Choudhury SR, Rodriguez B, Curb JD, Stamler J
    • Journal Title

      Am J Clin Nutr

      Volume: 88(2) Pages: 424-430

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] 予防医学の視点からみた栄養の現状と対策の視点(健康日本21をふまえて)2008

    • Author(s)
      奥田奈賀子、上島弘嗣
    • Journal Title

      栄養評価と治療

      Volume: 25 Pages: 114-117

    • Related Report
      2011 Final Research Report
  • [Journal Article] 日本人と脂質異常症の疫学コレステロール2008

    • Author(s)
      奥田奈賀子、上島弘嗣
    • Journal Title

      臨床栄養

      Volume: 113 Pages: 411-416

    • Related Report
      2011 Final Research Report
  • [Journal Article] 日本人と脂質異常症の疫学コレステロール2008

    • Author(s)
      奥田奈賀子
    • Journal Title

      臨床栄養 113

      Pages: 411-416

    • Related Report
      2010 Self-evaluation Report 2008 Annual Research Report
  • [Journal Article] 予防医学の視点からみた栄養の現状と対策の視点(健康日本21をふまえて)2008

    • Author(s)
      奥田奈賀子
    • Journal Title

      栄養評価と治療 25

      Pages: 114-117

    • Related Report
      2010 Self-evaluation Report 2008 Annual Research Report
  • [Journal Article] Cardiovascular disease and risk factors in Asia : a selected review2008

    • Author(s)
      Hirotsugu Ueshima
    • Journal Title

      Circulation 118

      Pages: 2702-2709

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Nutrient and food intakes of middle-aged adults at low risk of cardiova scular disease : the international study of macro-/micronutrients and blood pressure (INTERMAP)

    • Author(s)
      Shay CM, Okuda N, et al
    • Journal Title

      Eur J Nutr

      Volume: (Epub ahead)

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Presentation] Vegetable and fruit intake and CVD mortality in Japan : NIPPON DATA80 Nutrition Study 24year follow up2012

    • Author(s)
      奥田奈賀子、岡山明, 他
    • Organizer
      第76回日本循環器学会総会
    • Place of Presentation
      福岡市
    • Year and Date
      2012-03-18
    • Related Report
      2011 Annual Research Report
  • [Presentation] 高血圧治療中者の運動習慣と医療費健診受診者60万人の医療費分析(3)2011

    • Author(s)
      奥田奈賀子、岡山明, 他
    • Organizer
      第34回日本高血圧学会総会
    • Place of Presentation
      宇都宮市
    • Year and Date
      2011-10-21
    • Related Report
      2011 Annual Research Report
  • [Presentation] 保健事業の医療費評価研究-2女性の健診受診状況と医療費支出2011

    • Author(s)
      奥田 奈賀子
    • Organizer
      第21回日本疫学会総会
    • Place of Presentation
      札幌市 かでる2.7 北海道立道民活動センター
    • Year and Date
      2011-01-21
    • Related Report
      2010 Annual Research Report
  • [Presentation] 市販弁当の塩分は減らせるか? 第32回日本高血圧学会総会での減塩弁当の試み2010

    • Author(s)
      奥田 奈賀子
    • Organizer
      第33回日本高血圧学会総会
    • Place of Presentation
      福岡市 福岡国際会議場
    • Year and Date
      2010-10-15
    • Related Report
      2010 Annual Research Report
  • [Presentation] CVD Risk Factors and Nutrition : Findings from the INTERMAP Study.2010

    • Author(s)
      奥田奈賀子, 他
    • Organizer
      第74回日本循環器病学会
    • Place of Presentation
      京都市
    • Year and Date
      2010-03-07
    • Related Report
      2010 Self-evaluation Report
  • [Presentation] CVD Risk Factors and Nutrition : Findings from the INTERMAP Study2010

    • Author(s)
      奥田奈賀子
    • Organizer
      第74回日本循環器病学会
    • Place of Presentation
      京都市
    • Year and Date
      2010-03-07
    • Related Report
      2009 Annual Research Report
  • [Presentation] 職域における食事性脂質改善に重点をおいた高LDLコレステロール血症保健指導の実践2010

    • Author(s)
      奥田奈賀子、原めぐみ、三浦克之、門田文、藤吉朗、村上義孝、清水満理子、舩越傳、上島弘嗣、岡村智教
    • Organizer
      第46回日本循環器病予防学会
    • Place of Presentation
      東京
    • Related Report
      2011 Final Research Report 2010 Self-evaluation Report
  • [Presentation] 食塩摂取量と血圧の関連 : NIPPON DATA80国民栄養調査統合データセットより2009

    • Author(s)
      奥田奈賀子
    • Organizer
      第32回日本高血圧学会総会
    • Place of Presentation
      大津市
    • Year and Date
      2009-10-02
    • Related Report
      2009 Annual Research Report
  • [Presentation] 日本における多量飲酒者の栄養摂取の特徴 : INTERMAP Japan 研究より2009

    • Author(s)
      奥田奈賀子
    • Organizer
      第44回日本アルコール・薬物医学会総会
    • Place of Presentation
      横浜市
    • Year and Date
      2009-09-08
    • Related Report
      2009 Annual Research Report
  • [Presentation] Dietary Factors Related to Higher Small LDL Particle Concentration of Japanese-American Men in Hawaii Compared with Japanese Men in Japan : The INTERLIPID Study.2009

    • Author(s)
      Okuda N, et al.
    • Organizer
      49th Cardiovascular Disease Epidemiology and Prevention Annual Conference.
    • Place of Presentation
      米国フロリダ州タンパ
    • Year and Date
      2009-03-12
    • Related Report
      2010 Self-evaluation Report
  • [Presentation] Dietary Factors Related to Higher Small LDL Particle Concentration of Japanese-American Men in Hawaii Compared with Japanese Men in Japan : The INTERLIPID study2009

    • Author(s)
      Nagako Okuda
    • Organizer
      49th Cardiovascular Disease Epidemiology and Prevention Annual Conference
    • Place of Presentation
      米国フロリダ州タンパ
    • Year and Date
      2009-03-12
    • Related Report
      2008 Annual Research Report
  • [Presentation] 日本における多量飲酒者の栄養摂取の特徴 : INTERMAP Japan研究より2009

    • Author(s)
      奥田奈賀子、三浦克之、Turin TC, 上島弘嗣、中川秀昭、中村幸志、由田克士、松村康弘、岡山明
    • Organizer
      第44回日本アルコール・薬物医学会総会
    • Place of Presentation
      横浜市
    • Related Report
      2011 Final Research Report
  • [Presentation] Jeremiah Stamler for the INTERMAP Research Group.Dietary Factors Related to Higher Small LDL Particle Concentration of Japanese-American Men in Hawaii Compared with Japanese Men in Japan: The INTERLIPID Study2009

    • Author(s)
      Nagako Okuda, Katsuyuki Miura, Hirotsugu Ueshima, Akira Okayam, Shigeyuki Saitoh, Hideaki Nakagawa, Katshushi Yoshita, Kiyomi Sakata
    • Organizer
      49th Cardiovascular Disease Epidemiology and Prevention Annual Conference
    • Place of Presentation
      米国
    • Related Report
      2011 Final Research Report
  • [Presentation] NIPPON DATA80・90への国民栄養調査結果の結合2008

    • Author(s)
      奥田奈賀子, 他
    • Organizer
      日本疫学会総会
    • Place of Presentation
      金沢市
    • Year and Date
      2008-01-24
    • Related Report
      2010 Self-evaluation Report

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Published: 2008-04-01   Modified: 2016-04-21  

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