| Project/Area Number |
20590648
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Public health/Health science
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| Research Institution | Ehime University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
SAHEKI Shuichi 愛媛大学, 総合健康センター, 教授 (80145078)
KUSUMOTO Katsunori 愛媛大学, 総合健康センター, 准教授 (10326960)
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| Project Period (FY) |
2008 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2011: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2010: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2009: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2008: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
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| Keywords | 果物摂取 / 動脈硬化 / 体力 / 循環器疾患 / 高次機能 / 抗加齢作用 |
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| Research Abstract |
We conducted a prospective cohort study. A total of 10,000 participants living in communities, free of prior diagnosis of cardiovascular disease completed health check-up examination and food frequency questionnaire. About intake of mikan (mandarin oranges), daily intake of high season was negatively associated with risk of cardiovascular disease and mortality as was daily intake of annual average. Further we found U-shaped risk curve. Therefore we thought there were upper limit of adequate intake for mikan. In addition, when participants of 65 years old had a cognitive function comparable, if their atherosclerosis of carotid artery by ultrasound measurement were stronger, there was more decrease of those function at 5 years later. In conclusion, prevention of atherosclerosis up to 65 years oldwas important.
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