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The roles of unsaturated fatty acids in breast cancer risk and the responsiveness to treatment

Research Project

Project/Area Number 20590650
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Public health/Health science
Research InstitutionKagoshima University

Principal Investigator

KORIYAMA Chihaya  Kagoshima University, 医歯学総合研究科, 准教授 (30274814)

Co-Investigator(Kenkyū-buntansha) AKIBA Suminori  鹿児島大学, 医歯学総合研究科, 教授 (50145554)
KIJIMA Yuko  鹿児島大学, 医学部・歯学部附属病院, 助教 (60381175)
SHINGUJI MEGUMI  鹿児島大学, 医歯学総合研究科, 助教 (70418862)
Project Period (FY) 2008 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2010: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2009: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2008: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Keywords乳がん / 不飽和脂肪酸 / 治療感受性 / 遺伝子多型
Research Abstract

In the present study, the association between n-3 highly-unsaturated fatty acids in serum and the breast cancer risk was examined in taking account the risk factors of breast cancer such as age, obesity, reproductive history and other life styles. There was no significant difference in the ratios of arachidonic acid to EPA and DHA in blood serum between breast cancer case and control groups. There was a weakly-positive association between the ratio of arachidonic acid to DHA and depressive state in breast cancer patients.

Report

(4 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (12 results)

All 2011 2010 2009 2008 Other

All Journal Article (8 results) (of which Peer Reviewed: 8 results) Presentation (4 results)

  • [Journal Article] High-risk human papillomavirus in mammary gland carcinomas and non-neoplastic tissues of Mexican women : No evidence supporting a cause and effect relationship.2011

    • Author(s)
      Herrera-Goepfert, et al.
    • Journal Title

      Breast

      Volume: 20 Pages: 184-189

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Immediate breast reconstruction using autologous free dermal fat grafts provides better cospetic results for patients with upper inner cancerous lesions.2011

    • Author(s)
      Kijima, et al.
    • Journal Title

      Surg Today

      Volume: 41 Pages: 477-489

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Determination and characterization of hydroxylated polychlorinated biphenyls (OH-PCBs) in serum and adipose tissue of Japanese women diagnosed with breast cancer.2010

    • Author(s)
      Nomiyama K, Yonehara T, Yonemura S, Yamamoto M, Koriyama C, Akiba S, Shinohara R, Koga M.
    • Journal Title

      Environmental Science and Technology 44(8)

      Pages: 2890-2896

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Utility of the Gene Search breast lymph node assay for the rapid evaluation of sentinel lymph nodes in breast cancer2010

    • Author(s)
      Funasako, et al.
    • Journal Title

      Cancer

      Volume: 116 Pages: 4450-4455

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Determination and characterization of hydroxylated polychlorinated biphenyls(OH-PCBs)in serum and adipose tissue of Japanese women diagnosed with breast cancer2010

    • Author(s)
      Nomiyama, et al.
    • Journal Title

      Environmental Science and Technology 44

      Pages: 2890-2896

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Synchronous bilateral breast cancer in a male patient following hormone therapy for prostate cancer2009

    • Author(s)
      Kijima, et al.
    • Journal Title

      Int J Clin Oncol 14

      Pages: 249-253

    • NAID

      10025148286

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effect of clinicopathologic factors on visibility of colorectal polypswith FDG PET2009

    • Author(s)
      Naka jo M, et al.
    • Journal Title

      American Journal of Roentgenology 192

      Pages: 754-760

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Clinical and pathological evaluation of implanted free dermal fat grafts after breast cancer surgery : a retrospective analysis

    • Author(s)
      Kijima, et al.
    • Journal Title

      Surgery

      Volume: (in press)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Presentation] Prognostic role of HPV in adenocarcinomas of the breast and the lung2010

    • Author(s)
      Koriyama, et al.
    • Organizer
      日本癌学会
    • Place of Presentation
      大阪市、大阪
    • Year and Date
      2010-09-23
    • Related Report
      2010 Annual Research Report
  • [Presentation] Prognostic role of HPV in adenocarcinomas of the breast and the lung.2010

    • Author(s)
      Koriyama C, Kijima Y, Yanagi M, Khan N, Yoshinaka H, Natsugoe S, Eizuru Y, Akiba S.
    • Organizer
      69^<th> Annual Meeting of the Japanese Cancer Association.
    • Place of Presentation
      Osaka (Osaka)
    • Related Report
      2010 Final Research Report
  • [Presentation] Residual organochlorine levels in breast adipose tissue among Japanese women with breast cancer and benign tumor of the breast.2008

    • Author(s)
      Koriyama C, Shinkura R, Ando T, Yamamoto M, Koga M, Ryota S, Arizono K, Tsuji M, Sagara Y, Akiba S.
    • Organizer
      The second JCA-AACR Special Joint Conference.
    • Place of Presentation
      Awaji (Hyogo)
    • Related Report
      2010 Final Research Report
  • [Presentation] Residual organochlorine levels in breast adipose tissue among Japanesewomen with breast cancer and benign tumor of the breast2008

    • Author(s)
      Koriyama C, et al.
    • Organizer
      The second JCA-AACR Special Joint Conference
    • Place of Presentation
      淡路夢舞台国際会議場(兵庫県淡路市)
    • Related Report
      2008 Annual Research Report

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Published: 2008-04-01   Modified: 2016-04-21  

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