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The fracture risk assessment tool using bone mineral density, risk factors and biochemical marker of bone turnover

Research Project

Project/Area Number 20590661
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Public health/Health science
Research InstitutionKinki University

Principal Investigator

TAMAKI Junko  Kinki University, 医学部, 准教授 (90326356)

Co-Investigator(Kenkyū-buntansha) IKI Masayuki  近畿大学, 医学部, 教授 (50184388)
FUJITA Yuuki  近畿大学, 医学部, 助教 (10330797)
Project Period (FY) 2008 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2010: ¥390,000 (Direct Cost: ¥300,000、Indirect Cost: ¥90,000)
Fiscal Year 2009: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2008: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Keywords骨密度 / 脆弱性骨折 / 骨代謝マーカー / 高齢男性 / コホート研究 / リスク評価 / 骨粗鬆症骨折 / リスク要因
Research Abstract

We conducted a baseline survey of the FORMEN Study among 2182 Japanese men aged≧65 years in 2008. The baseline database which included biochemical markers of bone turnover was completed. The clinical risk factors for fragility fracture, such as body mass index, smoking habit, were indicated to be associated with low bone mass. Furthermore, the vertebral deformity assessment at the baseline among 2012 men was completed. We ascertained 29 fragility fracture events until 2010, which number has not been enough to develop the model. The fracture risk assessment model would be completed in 2012 when the 5-year follow-up survey of the FORMEN study is conducted.

Report

(4 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (35 results)

All 2011 2010 2009 Other

All Journal Article (7 results) (of which Peer Reviewed: 7 results) Presentation (26 results) Remarks (2 results)

  • [Journal Article] Alcohol intake and bone status in elderly Japanese men : Baseline data from the Fujiwara-kyo Osteoporosis Risk in Men (FORMEN) Study.2011

    • Author(s)
      Kouda K, Iki M, Fujita Y, Tamaki J, Yura A, Kadowaki E, Sato Y, Moon JS, Morikawa M, Tomioka K, Okamoto N, Kurumatani N
    • Journal Title

      Bone.

    • URL

      http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T4Y-52NW5P7-2&_user=6840639&_coverDate=04%2F21%2F2011&_rdoc=1&_fmt=high&_orig=gateway&_origin=gateway&_sort=d&_docanchor=&view=c&_searchStrId=1737087112&_rerunOrigin=google&_acct=C000009018&_version=1&_urlVersion=0&_userid=6840639&md5=0d2b64f817c824b02bf127d759c4fb64&searchtype=a

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Serum undercarboxylated osteocalcin levels are inversely associated with glycemic status and insulin resistance in an elderly Japanese male population : Fujiwara-kyo Osteoporosis Risk in Men (FORMEN) Study.2011

    • Author(s)
      Iki M, Tamaki, J, Fujita Y, Kouda K, Yura A, Kadowaki E, Sato Y, Moon JS, Tomioka K, Okamoto N, Kurumatani N
    • Journal Title

      Osteoporos Int.

    • URL

      http://www.springerlink.com/content/e8261050826168w1/

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Association between Vitamin K Intake from Fermented Soybeans, Natto, and Bone Mineral Density in Elderly Japanese Men : The Fujiwara-kyo Osteoporosis Risk in Men (FORMEN) Study.2011

    • Author(s)
      Fujita Y, Iki M, Tamaki J, Kouda K, Yura A, Kadowaki E, Sato Y, Moon JS, Tomioka K, Okamoto N, Kurumatani N
    • Journal Title

      Osteoporos Int.

    • URL

      http://www.springerlink.com/content/f748404w31m67818/

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Impact of smoking on bone mineral density and bone metabolism in elderly men : the Fujiwara-kyo Osteoporosis Risk in Men (FORMEN) study.2011

    • Author(s)
      Tamaki J, Iki M, Fujita Y, Kouda K, Yura A, Kadowaki E, Sato Y, Moon JS, Tomioka K, Okamoto N, Kurumatani N.
    • Journal Title

      Osteoporos Int.

      Volume: 22(1) Pages: 133-141

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Impact of smoking on bone mineral density and bone metabolism in elderly men : the Fujiwara-kyo Osteoporosis Risk in Men (FORMEN) study.2010

    • Author(s)
      Tamaki J, Iki M, Fujita Y, Kouda K, Yura A, Kadowaki E, Sato Y, Moon JS, Tomioka K, Okamoto N, Kurumatani N
    • Journal Title

      Osteoporos Int.

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] (Fujiwara-kyo Study Group). Design and baseline characteristics of a prospective cohort study for determinants of osteoporotic fracture in community-dwelling elderly Japanese men : the Fujiwara-kyo osteoporosis risk in men (FORMEN) study.2009

    • Author(s)
      Iki M, Fujita Y, Tamaki J, Kouda K, Yura A, Kadowaki E, Sato Y, Moon JS, Okamoto N, Kurumatani N
    • Journal Title

      BMC Musculoskelet Disord. 10

      Pages: 165-165

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Design and baseline characteristics of a prospective cohort study for determinants of osteoporotic fracture in community-dwellimg elderly Japanese men : the Fujiwara-kyo Osteoporosis Risk in Men(FORMEN)Study2009

    • Author(s)
      Masayuki Iki
    • Journal Title

      BMC Musculoskeletal Disorders 10

      Pages: 165-165

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Presentation] 藤原京スタディグループ.日本人高齢男性では血清低カルボキシル化オステオカルシン濃度が空腹時血糖値・ヘモグロビンA1c値と逆相関した。藤原京スタディ男性骨粗鬆症(FORMEN)研究2011

    • Author(s)
      伊木雅之
    • Organizer
      日本内分泌学会
    • Place of Presentation
      神戸
    • Related Report
      2010 Final Research Report
  • [Presentation] HMG-CoA還元酵素阻害剤は骨量低下を抑制するか-藤原京スタディ男性骨折コホート研究の断面検討2011

    • Author(s)
      玉置淳子,伊木雅之,藤田裕規,甲田勝康,由良晶子,門脇英子,佐藤裕保,文鐘聲,冨岡公子,岡本希,車谷典男
    • Organizer
      日本疫学会
    • Place of Presentation
      札幌
    • Related Report
      2010 Annual Research Report 2010 Final Research Report
  • [Presentation] 骨代謝における軽度・中等度腎機能低下の影響 ~藤原京スタディ男性骨粗鬆症コホート研究~2011

    • Author(s)
      藤田裕規,伊木雅之,玉置淳子,甲田勝康,由良晶子,門脇英子,佐藤裕保,文鐘聲,冨岡公子,岡本希,車谷典男
    • Organizer
      日本疫学会
    • Place of Presentation
      札幌
    • Related Report
      2010 Final Research Report
  • [Presentation] 骨代謝における軽度・中等度腎機能低下の影響~藤原京スタディ男性骨粗鬆症コホート研究~2011

    • Author(s)
      藤田裕規
    • Organizer
      日本疫学会
    • Place of Presentation
      札幌
    • Related Report
      2010 Annual Research Report
  • [Presentation] IMPACT OF SMOKING ON BONE MINERAL DENSITY IN ELDERLY MEN : THE FUJIWARA-KYO OSTEOPOROSIS RISK IN MEN(FORMEN)STUDY2010

    • Author(s)
      玉置淳子
    • Organizer
      The International Society For Clinical Densitometry
    • Place of Presentation
      米国テキサス州サンアトニオ市
    • Year and Date
      2010-03-10
    • Related Report
      2009 Annual Research Report
  • [Presentation] Baseline data of a cohort study for determinants of osteoporotic fracture in community-dwelling elderly Japanese men : the Fujiwara-kyo Osteoporosis Risk in Men(FORMEN)Study2010

    • Author(s)
      Masayuki Iki
    • Organizer
      国際疫学会西太平洋地域学術会議兼第20回日本疫学会学術総会
    • Place of Presentation
      埼玉県立大学
    • Year and Date
      2010-01-09
    • Related Report
      2009 Annual Research Report
  • [Presentation] Serum undercarboxylated osteocalcin levels are inversely associated with glycemic status and insulin resistance in an elderly Japanese male population: Fujiwara-kyo Osteoporosis Risk in Men (FORMEN) Study.2010

    • Author(s)
      Iki M, Tamaki J, Fujita Y, Kouda K, Yura A, Kadowaki E, Sato Y, Moon JS, Tomioka K, Okamoto N, Kurumatani N
    • Organizer
      IOF Asian-Pacific Osteoporosis Meeting
    • Place of Presentation
      Singapore
    • Related Report
      2010 Final Research Report
  • [Presentation] 習慣的牛乳飲用は男性高齢者でも高骨密度に関連する-藤原京スタディ男性骨粗鬆症研究2010

    • Author(s)
      佐藤裕保,伊木雅之,藤田裕規,玉置淳子,甲田勝康,由良晶子,門脇英子, 文鐘聲,冨岡公子,岡本希,車谷典男
    • Organizer
      日本公衆衛生学会
    • Place of Presentation
      東京
    • Related Report
      2010 Final Research Report
  • [Presentation] 高齢者における慢性腎臓病有病状況とその循環器リスク要因への影響-藤原京スタディ-2010

    • Author(s)
      伊木雅之,玉置淳子,藤田裕規,甲田勝康,由良晶子,門脇英子,冨岡公子,岡本希,車谷典男
    • Organizer
      日本公衆衛生学会
    • Place of Presentation
      東京
    • Related Report
      2010 Annual Research Report 2010 Final Research Report
  • [Presentation] 日本人高齢男性では、推定糸球体濾過量は骨密度と逆相関した -藤原京スタディ男性骨粗鬆症(FORMEN)研究-2010

    • Author(s)
      伊木雅之,藤田裕規,玉置淳子,甲田勝康,由良晶子,門脇英子,佐藤裕保,文鐘聲,岡本希,車谷典男
    • Organizer
      日本骨粗鬆症学会
    • Place of Presentation
      大阪
    • Related Report
      2010 Final Research Report
  • [Presentation] 日本人高齢男性では血清オステオカルシン濃度は空腹時血糖値、並びにヘモグロビンA1c値と逆相関する。藤原京スタディ男性骨粗鬆症(FORMEN)研究2010

    • Author(s)
      伊木雅之,藤田裕規,玉置淳子,甲田勝康,由良晶子,門脇英子,佐藤裕保,岡本希,車谷典男
    • Organizer
      日本骨代謝学会
    • Place of Presentation
      東京
    • Related Report
      2010 Final Research Report
  • [Presentation] 適度な飲酒は骨粗鬆症を防ぐ-藤原京スタディ男性骨粗鬆症コホート研究-2010

    • Author(s)
      甲田勝康,伊木雅之,藤田裕規,玉置淳子,由良晶子,門脇英子,佐藤裕保,文鐘聲,森川,冨岡公子,岡本希,車谷典男
    • Organizer
      日本公衆衛生学会
    • Place of Presentation
      奈良
    • Related Report
      2010 Final Research Report
  • [Presentation] 禁煙は骨密度低下の速度を下げる-藤原京スタディ男性骨粗鬆症コホート研究の断面検討2010

    • Author(s)
      玉置淳子,伊木雅之,藤田裕規,甲田勝康,由良晶子,門脇英子,佐藤裕保,文鐘聲,冨岡公子,岡本希,車谷典男
    • Organizer
      日本公衆衛生学会
    • Place of Presentation
      奈良
    • Related Report
      2010 Final Research Report
  • [Presentation] 納豆摂取による骨密度低下の予防効果 ~藤原京スタディ男性骨粗鬆症コホート研究~2010

    • Author(s)
      藤田裕規,伊木雅之,玉置淳子,甲田勝康,由良晶子,門脇英子,佐藤裕保,文鐘聲,冨岡公子,岡本希,車谷典男
    • Organizer
      日本公衆衛生学会
    • Place of Presentation
      奈良(優秀演題賞)
    • Related Report
      2010 Final Research Report
  • [Presentation] 捨て置かれし男性の骨を守ろう!藤原京スタディ男性骨粗鬆症コホート研究の発進2010

    • Author(s)
      伊木雅之,藤田裕規,玉置淳子,甲田勝康,由良晶子,門脇英子,佐藤裕保,文鐘聲,岡本希,車谷典男
    • Organizer
      日本公衆衛生学会
    • Place of Presentation
      奈良
    • Related Report
      2010 Final Research Report
  • [Presentation] 藤原京スタディ男性骨粗鬆症コホート研究の発進2010

    • Author(s)
      伊木雅之,藤田裕規,玉置淳子,甲田勝康,由良晶子,門脇英子,佐藤裕保,文鐘聲,岡本希,車谷典男
    • Organizer
      日本骨粗鬆症学会
    • Place of Presentation
      名古屋
    • Related Report
      2010 Final Research Report
  • [Presentation] SUBCLINICAL DECLINE IN RENAL FUNCTION WAS ASSOCIATED WITH INCREASED BONE DENSITY IN A JAPANESE ELDERLY MALE POPULATION : FORMEN STUDY.2010

    • Author(s)
      Iki M, Fujita Y, Tamaki J, Kouda K, Yura A, Kadowaki E, Sato Y, Moon JS, Tomioka K, Okamoto N, Kurumatani N
    • Organizer
      IOF-ECCEO10
    • Place of Presentation
      Firenze
    • Related Report
      2010 Final Research Report
  • [Presentation] Baseline data of a cohort study for determinants of osteoporotic fracture in community-dwelling elderly Japanese men : the Fujiwara-kyo Osteoporosis Risk in Men (FORMEN) Study.2010

    • Author(s)
      Iki M, Fujita Y, Tamaki J, Kouda K, Yura A, Kadowaki E, Sato Y, Moon JS, Morikawa M, Tomioka K, Okamoto N, Kurumatani N
    • Organizer
      IEQWP/JEA
    • Place of Presentation
      Koshigaya
    • Related Report
      2010 Final Research Report
  • [Presentation] SUBCLINICAL DECLINE IN RENAL FUNCTION WAS ASSOCIATED WITH INCREASED BONE DENSITY IN A JAPANESE ELDERLY MALE POPULATION : FORMEN STUDY.2010

    • Author(s)
      Iki M
    • Organizer
      IOF-ECCE010
    • Place of Presentation
      Firenze
    • Related Report
      2010 Annual Research Report
  • [Presentation] 日本人高齢男性では血清オステオカルシン濃度は空腹時血糖値、並びにヘモグロビンAlc値と逆相関する。藤原京スタディ男性骨粗鬆症(FORMEN)研究.2010

    • Author(s)
      伊木雅之
    • Organizer
      日本骨代謝学会
    • Place of Presentation
      東京
    • Related Report
      2010 Annual Research Report
  • [Presentation] 日本人高齢男性では、推定糸球体濾過量は骨密度と逆相関した-藤原京スタディ男性骨粗鬆症(FORMEN)研究-2010

    • Author(s)
      伊木雅之
    • Organizer
      日本骨粗鬆症学会
    • Place of Presentation
      大阪
    • Related Report
      2010 Annual Research Report
  • [Presentation] 習慣的牛乳飲用は男性高齢者でも高骨密に関連する-藤原京スタディ男性骨粗鬆症研究2010

    • Author(s)
      佐藤裕保
    • Organizer
      日本公衆衛生学会
    • Place of Presentation
      東京
    • Related Report
      2010 Annual Research Report
  • [Presentation] Serum undercarboxylated osteocalcin levels are inversely associated with glycemic status and insulin resistance in an elderly Japanese male population : Fujiwara-kyo Osteoporosis Risk in Men (FORMEN) Study.2010

    • Author(s)
      Iki M
    • Organizer
      IOF Asian-Pacific Osteoporosis Meeting
    • Place of Presentation
      Singapore
    • Related Report
      2010 Annual Research Report
  • [Presentation] 喫煙年数が長いほど骨密度は低い-藤原京スタディ男性骨粗鬆症コホート研究の断面検討2009

    • Author(s)
      玉置淳子
    • Organizer
      第68回日本公衆衛生学会
    • Place of Presentation
      奈良県文化会館
    • Year and Date
      2009-10-22
    • Related Report
      2009 Annual Research Report
  • [Presentation] 捨て置かれし男性の骨を守ろう!藤原京スタディ男性骨粗鬆症コホート研究の発進2009

    • Author(s)
      伊木雅之
    • Organizer
      第68回日本公衆衛生学会
    • Place of Presentation
      奈良県文化会館
    • Year and Date
      2009-10-22
    • Related Report
      2009 Annual Research Report
  • [Presentation] 納豆摂取による骨密度低下の予防効果~藤原京スタディ男性骨粗鬆症コホート研究2009

    • Author(s)
      藤田裕規
    • Organizer
      第68回日本公衆衛生学会
    • Place of Presentation
      奈良県文化会館
    • Year and Date
      2009-10-22
    • Related Report
      2009 Annual Research Report
  • [Remarks] Medical Tribune.2010 May 44;10:11.

    • Related Report
      2010 Final Research Report
  • [Remarks] 雑誌2件目掲載URL

    • URL

      http://www.biomedcentral.com/1471-2474/10/165

    • Related Report
      2009 Annual Research Report

URL: 

Published: 2008-04-01   Modified: 2016-04-21  

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