| Project/Area Number |
20590662
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Public health/Health science
|
|---|
| Research Institution | Kansai University of Welfare Sciences |
|---|
Principal Investigator |
KURATSUNE Hirohiko Kansai University of Welfare Sciences, 健康福祉学部, 教授 (50195533)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
TAJUIMA Seiki 兵庫県立総合リハビリテーションセンターリハビリテーション中央病院, 子どもの睡眠と発達医療センター, 医師 (30420722)
|
|---|
| Project Period (FY) |
2008 – 2010
|
| Project Status |
Completed (Fiscal Year 2010)
|
| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2010: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2009: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2008: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
|
|---|
| Keywords | 過重労働 / 疲労 / バイオマーカー / 自律神経機能 / 酸化ストレス / 産業疲労特定検診 / 心拍変動解析 / トータルパワー値 / 自律神経系バランス(IF/HF比) / 主観的疲労度 / アクティグラフ / 唾液アミラーゼ |
|---|
| Research Abstract |
We studied the fatigue state of crushing labor by using not only a questionnaire, but also several objective biomarkers such as the autonomic function, the amount and intensity of human activity, and the oxidation and anti-oxidation activities. The results from the autonomic function judging by the A-A interval power spectrum analysis for acceleration plethysmogram lead to early detection of the mental health disorders and the fatigue state without feeling of fatigue. Most of them who had sympathetic hyperactivity in the rest with closed eyes had a deterioration of sleep quality. Furthermore, the evaluation of oxidation and anti-oxidation activities by using the d-ROMs test and the BAP test reflects not only the clinical condition with or without fatigue state, but also the etiology of fatigue state. Therefore, these evaluations might make useful objective markers for diagnostic evaluation of fatigue states.
|
