| Project/Area Number |
20590663
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Public health/Health science
|
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| Research Institution | Kurume University |
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Principal Investigator |
ADACHI Hisashi Kurume University, 医学部, 教授 (40212518)
|
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| Co-Investigator(Kenkyū-buntansha) |
KUMAGAE ShunーIchi 久留米大学, 医学部, 助教 (20412504)
NANJO Yasuki 久留米大学, 医学部, 助教 (70461431)
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| Project Period (FY) |
2008 – 2010
|
| Project Status |
Completed (Fiscal Year 2010)
|
| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2010: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2009: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2008: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Keywords | 疫学 / 心拍数 / メタボリック症候群 / 地域住民 |
|---|
| Research Abstract |
We investigated whether resting heart rate by an electrocardiogram (ECG) may be a useful predictor for the development of the metabolic syndrome in a general population. Our prospective study revealed that higher heart rate predispose to obesity, diabetes mellitus, and insulin resistance syndrome. More importantly, we have demonstrated that higher heart rate >=80bpm at baseline predicted the development of insulin resistance. Our results may suggest that a causative role of sympathetic activation in the development of obesity and diabetes. This is the first prospective reports demonstrating that higher heart rate at baseline is strongly associated with insulin resistance 20 years later.
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