The effects of lifestyle modification on metabolic syndrome : a meta-analysis

• Project/Area Number: 20590668
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Public health/Health science
• Research Institution: National Institute of Public Health
• Principal Investigator: 山岡 和枝 National Institute of Public Health, 技術評価部, 開発技術評価室長 (50091038)
• Co-Investigator(Renkei-kenkyūsha): 丹後 俊郎 昭和女子大学, 大学院・生活機構研究科 (70124477) ; 飛田 英祐 国立保健医療科学院, 技術評価部, 主任研究官 (30469952)
• Project Period (FY): 2008 – 2010
• Project Status: Completed (Fiscal Year 2010)
• Budget Amount: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000); Fiscal Year 2010: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000); Fiscal Year 2009: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000); Fiscal Year 2008: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
• Keywords: 健康教育 / 生活習慣 / メタボリックシンドローム / メタアナリシス / 評価 / システマティックレビュー / 診断基準 / 統合値 / メタ・アナリシス / システマティック・レビュー / 教育

Research Abstract

Determining the effect of lifestyle modification on metabolic syndrome (MetS) is important. However, the worldwide diagnostic criterion for MetS and its components is not unified yet. We have developed MetS-simulator that calculative prevalence of MetS corresponding to several diagnostic criteria based on the checkup result in a group. A meta-analysis was conducted to examine the effects of lifestyle modification on MetS. The rate difference of the rate free from metabolic syndrome and mean differences of its components in the lifestyle education intervention group compared with the control group were analyzed using complete data as well as the data including the estimated data by MetS-simulator. Simple and multiple meta-analyses were conducted using random-effects model and so on. The result suggested the effectiveness of the lifestyle modification.

Research Products

• [Journal Article] 統計的メタボリックシンドローム・シミュレータの開発 (2010)
  • Author(s): 圖師誠,山岡和枝,渡辺満利子,丹後俊郎
  • Journal Title: 日本公衆衛生学会誌 12 Pages: 1043-1134
  • NAID: 10027680049
• [Journal Article] Effects of lifestyle education program for type 2 diabetes patients in clinics : study design of a cluster randomized trial. (2010)
  • Author(s): Adachi M, Yamaoka K, Watanabe M, Nishikawa M, Hida E, Kobayashi I, Tango T
  • Journal Title: BMC Public Health. 10(1) Pages: 742-742
• [Journal Article] Validity and Reproducibility of the Food Frequency Questionnaire (FFQW82) for Dietary Assessment in Female Adolescents. (2010)
  • Author(s): Watanabe M, Yamaoka K, Adachi M, Yokotsuka M, Tango T
  • Journal Title: Public Health Nutrition 14(2) Pages: 297-305
• [Journal Article] 栄養教育のための食物摂取頻度調査票(FFQW82)の妥当性と再現性の検討 (2010)
  • Author(s): 安達美佐,渡辺満利子,山岡和枝,丹後俊郎
  • Journal Title: 日本公衆衛生学会誌 57 Pages: 475-485
  • NAID: 10026598352
• [Journal Article] シンポジウム「学術領域における評価のデザイン-RCTとシステマティック・レビューの現状-」2.栄養領域のRCTとSR (2010)
  • Author(s): 山岡和枝,丹後俊郎
  • Journal Title: Jpn Pharmacol Ther(薬理と治療) 37 Pages: 1-14
• [Journal Article] Assignment of grouped exposure levels for trend estimation in a regression analysis of summarized data. (2010)
  • Author(s): Takahashi K, Tango T
  • Journal Title: Statistics in Medicine 29 Pages: 2605-2616
• [Journal Article] 統計的メタポリックシンドローム・シミュレータの開発 (2010)
  • Author(s): 圖師誠, 山岡和枝, 渡辺満利子, 丹後俊郎
  • Journal Title: 日本公衆衛生学会誌 Volume: 12 Pages: 1043-1134
  • Peer Reviewed
• [Journal Article] シンポジウム「学術領域における評価のデザイン-RCTとシステマティック・レビューの現状-」2.栄養領域のRCTとSR. (2010)
  • Author(s): Yamaoka K, Tango T
  • Journal Title: Jpn Pharmacol Ther(薬理と治療) Volume: 37 Pages: 1-14
  • Peer Reviewed
• [Journal Article] On the three-arm non-inferiority trial including a placebo with a prespecified margin (2010)
  • Author(s): Hida E, Tango T
  • Journal Title: Statistics in Medicine Pages: 224-231
  • Peer Reviewed
• [Journal Article] Impact of group based dietary education on dietary habit for female adolescents : A cluster randomized trial (2010)
  • Author(s): Yamaoka K, Watanabe M, Hida E, Tango T.
  • Journal Title: Public Health Nutrition Pages: 702-709
  • Peer Reviewed
• [Journal Article] Assignment of grouped exposure levels for trend estimation in a regression analysis of summarized data (2010)
  • Author(s): Takahashi K, Tango T
  • Journal Title: Statistics in Medicine Volume: 29 Pages: 2605-2616
  • Peer Reviewed
• [Journal Article] Effects of lifestyle education program for type 2 diabetes patients inclinics : study design of a cluster randomized trial (2010)
  • Author(s): Adachi M, Yamaoka K, Watanabe M, Nishikawa M, Hida E, Kobayashi I, Tango T
  • Journal Title: BMC Public Health Volume: 10(1) Pages: 742-742
  • Peer Reviewed
• [Journal Article] Validity and Reproducibility of the Food Frequency Questionnaire (FFQW82) for Dietary Assessment in Female Adolescents. (2010)
  • Author(s): Watanabe, M, Yamaoka K, Adachi M, Yokotsuka M, Tango T
  • Journal Title: Public Health Nutrition Volume: 14(2) Pages: 297-305
  • Peer Reviewed
• [Journal Article] 栄養教育のための食物摂取頻度調査票(FFQW82)の妥当性と再現性の検討 (2010)
  • Author(s): 安達美佐, 渡辺満利子, 山岡和枝, 丹後俊郎
  • Journal Title: 日本公衆衛生学会誌 Volume: 57 Pages: 475-485
  • NAID: 10026598352
  • Peer Reviewed
• [Journal Article] シンポジウム「学術領域における評価のデザイン-RCTとシステマティック・レビューの現状-」2.栄養領域のRCTとSR. (2010)
  • Author(s): Yamaoka K, Tango T
  • Journal Title: Jpn Pharmacol Ther(薬理と治療)(査読無) 37 Pages: 1-14
  • Peer Reviewed
• [Journal Article] Statistical tests based on new composite hypotheses in clinical trials reflecting the relative clinical importance of multiple endpoints quantitatively. (2009)
  • Author(s): Nishikawa M, Tango T, Ohtaki M
  • Journal Title: Biometrical Journal 51 Pages: 749-762
• [Journal Article] Permutation test following covariate-adaptive randomization in randomized controlled trials. (2009)
  • Author(s): Hasegawa T, Tango T
  • Journal Title: Journal of Biopharmaceutical Statistics 19 Pages: 106-119
• [Journal Article] Permutation test following covariate-adaptive randomization in randomized controlled trials (2009)
  • Author(s): Hasegawa T, Tango T.
  • Journal Title: J Biopharm Stat 19(1) Pages: 106-119
  • Peer Reviewed
• [Journal Article] Systematic review and a meta-analysis for the efficacy of lifestyle education to prevent type 2 diabetes : an update version.(English) La educacion sobre el estilo de vida es eficaz para reducir la glucemia 2 horas despues de una carga oral de glucosa y la incidencia de diabetes tipo 2 en grupos de individuos de alto riesgo. (Spanish) (2008)
  • Author(s): 山岡和枝, 丹後俊郎
  • Journal Title: Sociedad Iberoamericana de Informaci n Cient fica (SIIC)
  • URL: http://www.siicsalud.com/dato/experto.php/89771
• [Journal Article] Systematic review and a meta-analysis for the efficacy of lifestyle education to prevent type 2 diabetes : an update version (2008)
  • Author(s): Yamaoka K, Tango T
  • Journal Title: Sociedad Iberoamericana de Informaci n Cientfica (SIIC) 2008 http://www.siicsalud.com/dato/experto.php/89771
  • Peer Reviewed
• [Journal Article] 標準化死亡比の経験的ベイズ推定量に基づく医療資源と死亡との関連:全国の市区町村を対象として (2008)
  • Author(s): 大坪浩一, 山岡和枝, 横山徹爾, 高橋邦彦, 西川正子, 丹後俊郎
  • Journal Title: 日本公衆衛生雑誌 56(2) Pages: 101-110
  • NAID: 10026522806
  • Peer Reviewed
• [Journal Article] Sample size formula for randomized controlled trials with counts of recurrent events (2008)
  • Author(s): Tango T
  • Journal Title: Statistics and Probability Letters (In press)
  • Peer Reviewed
• [Journal Article] On the three-arm non-inferiority trial including a placebo with a prespecified margin.
  • Author(s): Hida E, Tango T
  • Journal Title: Statistics in Medicine (in press, published online)
• [Journal Article] Impact of group based dietary education on dietary habit for female adolescents : A cluster randomized trial.
  • Author(s): Yamaoka K, Watanabe M, Hida E, Tango T
  • Journal Title: Public Health Nutrition (in press, published online)
• [Presentation] メタボリックシンドロームのための生活習慣改善プログラム効果の評価-無作為化比較試験に基づく研究プロトコル- (2011)
  • Author(s): 渡辺満利子,山岡和枝,安達美佐,横塚昌子,橋本夕紀恵,丹後俊郎
  • Organizer: 第21回日本疫学会学術総会(講演集Journal of Epidemiology, p291)
  • Place of Presentation: 札幌市
  • Year and Date: 2011-01-22
• [Presentation] 地域における2型糖尿病のための生活習慣改善プログラムによる介入効果の評価-クラスター無作為化比較試験の研究デザインおよびベースライン結果- (2011)
  • Author(s): 安達美佐,山岡和枝,渡辺満利子,小林逸郎,西川正子,飛田英祐,丹後俊郎
  • Organizer: 第21回日本疫学会学術総会(講演集Journal of Epidemiology, p292)
  • Place of Presentation: 札幌市
  • Year and Date: 2011-01-22
• [Presentation] メタボリックシンドロームのための生活習慣改善プログラム効果の評価・無作為化比較試験に基づく研究プロトコル- (2011)
  • Author(s): 渡辺満利子, 山岡和枝, 安達美佐, 横塚昌子, 橋本夕紀恵, 丹後俊郎
  • Organizer: 第21回日本疫学会学術総会
  • Place of Presentation: 札幌市
  • Year and Date: 2011-01-22
• [Presentation] 地域における2型糖尿病のための生活習慣改善プログラムによる介入効果の評価-クラスター無作為化比較試験の研究デザインおよびベースライン結果- (2011)
  • Author(s): 安達美佐, 山岡和枝, 渡辺満利子, 小林逸郎, 西川正子, 飛田英祐, 丹後俊郎
  • Organizer: 第21回日本疫学会学術総会
  • Place of Presentation: 札幌市
  • Year and Date: 2011-01-22
• [Presentation] The effects of lifestyle modification on MetS : a multivariate meta-analysis using mets-simulator. (2010)
  • Author(s): Yamaoka K, Zushi M, Hida E, Tango T
  • Organizer: The 25th International Biometrics Conference(Programme P45)
  • Place of Presentation: Florianopolis, Brazil
  • Year and Date: 2010-12-10
• [Presentation] The effects of lifestyle modification on MetS : amultivariatemeta-analysis using wets-simulator. (2010)
  • Author(s): Yamaoka K, Zushi M, Hida E, Tango T
  • Organizer: The 25th International Biometrics Conference
  • Place of Presentation: Florianopolis, Brazil
  • Year and Date: 2010-12-10
• [Presentation] RCTに基づくメタボ改善プログラム介入研究のための基礎データ解析 (2010)
  • Author(s): 渡辺満利子,山岡和枝,安達美佐,横塚昌子,橋本夕紀恵,丹後俊郎
  • Organizer: 第69回日本公衆衛生学会(日本公衆衛生学雑誌57,10:p526-527)
  • Place of Presentation: 東京都
  • Year and Date: 2010-10-29
• [Presentation] RCTに基づくメタポ改善プログラム介入研究のための基礎データ解析 (2010)
  • Author(s): 渡辺満利子, 山岡和枝, 安達美佐, 横塚昌子, 橋本夕紀恵, 丹後俊郎
  • Organizer: 第69回日本公衆衛生学会
  • Place of Presentation: 東京都
  • Year and Date: 2010-10-29
• [Presentation] 隣接地域の影響を考慮した医療費地域差指数のベイズ推定 (2010)
  • Author(s): 高橋邦彦,飛田英佑,山岡和枝,丹後俊郎
  • Organizer: 第69回日本公衆衛生学会(日本公衆衛生学雑誌57,10:p485)
  • Place of Presentation: 東京都
  • Year and Date: 2010-10-28
• [Presentation] 隣接地域の影響を考慮した医療費地域差指数のベイズ推定 (2010)
  • Author(s): 高橋邦彦, 飛田英佑, 山岡和枝, 丹後俊郎
  • Organizer: 第69回日本公衆衛生学会
  • Place of Presentation: 東京都
  • Year and Date: 2010-10-28
• [Presentation] 特発性肺線維症の急性増悪の予後因子に関する統計学的検討 (2010)
  • Author(s): 勝田知也,山岡和枝,丹後俊郎
  • Organizer: 2010年度日本計量生物学会年会
  • Place of Presentation: 統計数理研究所
  • Year and Date: 2010-05-21
• [Presentation] 特発性肺線維症の急性増悪の予後因子に関する統計学的検討 (2010)
  • Author(s): 勝田知也, 山岡和枝, 丹後俊郎
  • Organizer: 2010年度日本計量生物学会年会
  • Place of Presentation: 東京都
  • Year and Date: 2010-05-21
• [Presentation] The statically analysis of prognosis factor in acute exacerbation of idiopathic pulmonary fibrosis. (2010)
  • Author(s): Katsuta T, Yamaoka K, Tango T
  • Organizer: 31th Annual Conference of the International Society for Clinical Biostatistics.(France Programme & Abstract Book p.89-90)
  • Place of Presentation: Universiy of Monpellie, Monpellie
• [Presentation] A sensitivity analysis using multiple imputation method for meta-analysis : the effects of lifestyle modification on metabolic syndrome. (2010)
  • Author(s): Yamaoka K, Zushi M, Tango T
  • Organizer: East Asia Regional Biometric Conference
  • Place of Presentation: India
• [Presentation] Geographical clustering of caries prevalence on 3-year-old children in Hokkaido. (2010)
  • Author(s): Aida J, Takahashi K, Yamaoka K, Tango T, Akino K, Osaka K
  • Organizer: 国際疫学会西太平洋地域学術会議兼第20回日本疫学会学術総会
  • Place of Presentation: 埼玉県立大学
• [Presentation] A sensitivity analysis using multiple imputation method for meta-analysis : the effects of lifestyle modification on metabolic syndrome. (2010)
  • Author(s): Yamaoka K, Zushi M, Tango T
  • Organizer: East Asia Regional Biometric Conference 2010
  • Place of Presentation: India
• [Presentation] The statically analysis of prognosis factor in acute exacerbation of idiopathic pulmonary fibrosis (2010)
  • Author(s): Katsuta T, Yamaoka K, Tango T
  • Organizer: 31th Annual Conference of the International Society for Clinical Biostatistics
  • Place of Presentation: University of Monpellie, Monpellie, France
• [Presentation] A sensitivity analysis using multiple imputation method for meta-analysis : the effects of lifestyle modification on metabolic syndrome (2010)
  • Author(s): 山岡和枝, 圖師誠, 丹後俊郎
  • Organizer: East Asia Regional Biometric Conference
  • Place of Presentation: Maniple, India
• [Presentation] メタアナリシスの応用:糖尿病予防のための生活習慣教育の効果の評価 (2009)
  • Author(s): 山岡和枝,丹後俊郎
  • Organizer: 第1回Evidence-based Anesthesia研究会
  • Place of Presentation: (松本市)長野県松本文化会館
  • Year and Date: 2009-09-26
• [Presentation] メタアナリシスの応用:糖尿病予防のための生活習慣教育の効果の評価 (2009)
  • Author(s): 山岡和枝・丹後俊郎
  • Organizer: 第1回 Evidence-based Anesthesia 研究会
  • Place of Presentation: 松本市
  • Year and Date: 2009-09-26
• [Presentation] 統計的メタボリックシンドローム・シミュレータの開発に関する研究 (2009)
  • Author(s): 圖師誠,山岡和枝,渡辺満利子,丹後俊郎
  • Organizer: 2009年度統計関連学会連合大会講演報告集(p.155)
• [Presentation] A cluster randomized controlled trials of a new dietary education for female adolescents (2009)
  • Author(s): Yamaoka K, Watanabe M, Hida E, Tango T
  • Organizer: 30th Annual Conference of the International Society for Clinical Biostatistics
  • Place of Presentation: University of Economics, Prague, Czech Republic
• [Presentation] 統計的メタボリックシンドローム・シミュレータの開発に関する研究 (2009)
  • Author(s): 圖師誠, 山岡和枝, 渡辺満利子, 丹後俊郎
  • Organizer: 2009年度統計関連学会連合大会
  • Place of Presentation: 同志社大学, 京田辺市
• [Presentation] Multivariate multilevel analyses of the influence of social capital on self-rated perceptions of health : Multivariate response models with missing data (2008)
  • Author(s): Yamaoka K, Tango T
  • Organizer: The 24th International Biometrics Conference
  • Place of Presentation: Dublin, Ireland
  • Year and Date: 2008-07-17
• [Presentation] A spatial scan statistic with a modified likelihood ratio (2008)
  • Author(s): Tango T
  • Organizer: The 24th International Biometrics Conference
  • Place of Presentation: Dublin, Ireland
• [Presentation] Evaluation of cross-cultural equivalence of QOL measures in clinical trials settings : a mixture model (2008)
  • Author(s): Yamaoka K, Tango T, et al.
  • Organizer: 29th Annual Conference of the International Society for Clinical Biostatistics
  • Place of Presentation: Copenhagen, Denmark
• [Book] 医学統計学の事典(ISBN:978-4-254-12176-6 C3541) (2010)
  • Author(s): 丹後俊郎,小西貞則編
  • Publisher: 朝倉書店
• [Book] 医学統計学の事典 (2010)
  • Author(s): 丹後俊郎, 小西貞則編
  • Total Pages: 472
  • Publisher: 朝倉書店