| Project/Area Number |
20590677
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Legal medicine
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| Research Institution | Kobe University |
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Principal Investigator |
UENO Yasuhiro Kobe University, 大学院・医学研究科, 教授 (30184956)
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| Co-Investigator(Kenkyū-buntansha) |
ASANO Migiwa 神戸大学, 大学院・医学研究科, 准教授 (90283879)
OKAMOTO Maya 神戸大学, 大学院・医学研究科, 学術推進研究員 (10444209)
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| Project Period (FY) |
2008 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2010: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2009: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2008: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
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| Keywords | 乳幼児突然死症候群 / 脂質代謝 / カルニチン / 抗酸化作用 / 暑熱ストレス / 乳幼児突然死症候群(SIDS) / 脂質代謝異常 / 小腸上皮細胞(Caco-2) / 膠芽腫細胞(GL261) / セネッセンス / 突然死 / 環境因子 |
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| Research Abstract |
To clarify the basic mechanism of sudden infant death syndrome (SIDS), we examined several studies from the standpoint of both biochemistry and epidemiology : i) Evaluation of intestinal absorption of carnitine by the difference of its molecular structure using intestinal cell culture model, ii) Mechanism of senescence and anti-aging effect of carnitine in mouse glioblastoma, iii) A comparative study of daily maximum and personally exposed temperatures during hot summer days in Kobe, Japan.
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