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APPLICATION OF POLYMORPHISMS AT PIGMENTATION GENES TO PERSONAL IDENTIFICATION

Research Project

Project/Area Number 20590678
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Legal medicine
Research InstitutionTottori University

Principal Investigator

YUASA Isao  Tottori University, 医学部, 准教授 (00093633)

Co-Investigator(Kenkyū-buntansha) IRIZAWA Yoshito  鳥取大学, 医学部, 教授 (90112226)
Co-Investigator(Renkei-kenkyūsha) UMETSU Kazuo  山形大学, 医学部, 准教授 (10091828)
AKANE Atsushi  関西医科大学, 医学部, 教授 (70202520)
Project Period (FY) 2008 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2009: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2008: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Keywords色素形成遺伝子 / 多型 / 個人識別 / 帰属集団 / 祖先集団
Research Abstract

Personal identification is one of the most important investigations in forensics, and the STR polymorphisms are usually used all over the world. However, the investigation of STR does not provide information of the ancestry and population to which an individual belongs. In this study, the frequencies of pigmentation gene polymorphisms and new East Asian- and Japanese-specific alleles were investigated. On the basis of these data, methods were developed for the inference.

Report

(4 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (50 results)

All 2011 2010 2009 2008 Other

All Journal Article (35 results) (of which Peer Reviewed: 9 results) Presentation (14 results) Book (1 results)

  • [Journal Article] Simultaneous determination of seven informative Y chromosome SNPs to differentiate East Asian, European and African populations.2011

    • Author(s)
      Muro T, Iida R, Fujihara J, Yasuda T, Watanabe Y, Imamura S, Nakamura H, Kimura-Kataoka K, Yuasa I, Toga T, Takeshita H
    • Journal Title

      Legal Medicine 13(3)

      Pages: 134-141

    • Related Report
      2010 Final Research Report
  • [Journal Article] Genetic variants associated with arsenic metabolism within human arsenic (+3 oxidation state) methyltransferase (AS3MT) show wide variation across multiple populations.2011

    • Author(s)
      Fujihara J, Yasuda T, Kato H, Yuasa I, Panduro A, Kunito T, Takeshita H
    • Journal Title

      Archives of Toxicology 85(2)

      Pages: 119-125

    • Related Report
      2010 Final Research Report
  • [Journal Article] A hypervariable STR polymorphism in the complement factor I (CFI) gene : Asian-specific alleles.2011

    • Author(s)
      Yuasa I, Irizawa Y, Nishimukai H, Fukumori Y, Umetsu K, Nakayashiki N, Saitou N, Henke L, Henke J
    • Journal Title

      International Journal of Legal Medicine 125(1)

      Pages: 121-125

    • Related Report
      2010 Final Research Report
  • [Journal Article] A hypervariable STR polymorphism in the complement factor I (CFI) gene : Asian-specific alleles.2011

    • Author(s)
      Isao Yuasa, 他8名
    • Journal Title

      International Journal of Legal Medicine

      Volume: 125 Pages: 121-125

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Global analysis of single nucleotide polymorphisms in the exons of human deoxyribose I-like 1 and 2 genes.2010

    • Author(s)
      Fujihara J, Yasuda T, Iida R, Kimura-Kataoka K, Soejima M, Koda Y, Kato H, Panduro A, Yuasa I, Takeshita H
    • Journal Title

      Electrophoresis 31(21)

      Pages: 3552-3557

    • Related Report
      2010 Final Research Report
  • [Journal Article] Genetic and expression analysis of all non-synonymous single nucleotide polymorphisms in the human deoxyribonuclease I-like 1 and 2 genes.2010

    • Author(s)
      Ueki M, Fujihara J, Takeshita H, Kimura-Kataoka K, Iida R, Nakajima T, Kominato Y, Yuasa I, Yasuda T
    • Journal Title

      Electrophoresis 31(12)

      Pages: 2063-2069

    • Related Report
      2010 Final Research Report
  • [Journal Article] A Japanese- specific allele. at the GALNT11 gene.2010

    • Author(s)
      Yuasa I, Umetsu K, Matsusue A, Nishimukai H, Fukumori Y, Harihara S, Saitou N, Jin F, Chattopadhyay PK, Henke L, Henke J
    • Journal Title

      Legal Medicine 12(4)

      Pages: 208-211

    • NAID

      10027576110

    • Related Report
      2010 Final Research Report
  • [Journal Article] The genotypes of IL-1 beta and MMP-3 are associated with the prognosis of HCV-related hepatocellular carcinoma.2010

    • Author(s)
      Okamoto K, Ishida C, Ikebuchi Y, Mandai M, Mimura K, Murawaki Y, Yuasa I
    • Journal Title

      Internal Medicine 49(10)

      Pages: 887-895

    • NAID

      130000251558

    • Related Report
      2010 Final Research Report
  • [Journal Article] A decreasing cline of 374F allele frequencies in the skin pigmentation gene SLC45A2 from the north of West Europe to North Africa Biochemical Genetics2010

    • Author(s)
      Lucotte G, Mercier G, Dieterlen F, Yuasa I
    • Journal Title

      48(1-2)

      Pages: 26-33

    • Related Report
      2010 Final Research Report
  • [Journal Article] Genetic and expression analysis of all 7 non-synonymous single nucleotide polymorphisms in the human deoxyribonuclease II gene, with potential relevance to autoimmunity.2010

    • Author(s)
      Ueki M, Takeshita H, Fujihara J, Kimura-Kataoka K, Iida R, Yuasa I, Nakajima T, Kominato Y, Yasuda T
    • Journal Title

      Clinica Chimica Acta 411(1-2)

      Pages: 92-98

    • Related Report
      2010 Final Research Report
  • [Journal Article] A decreasing cline of 374F allele frequencies in the skin pigmentation gene SLC45A2 from the north of West Europe to North Africa.2010

    • Author(s)
      G.Lucotte, Isao Yuasa, 他2名
    • Journal Title

      Biochemical Genetics

      Volume: 48 Pages: 26-33

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A Japanese-specific allele at the GALNT 11 gene.2010

    • Author(s)
      Isao Yuasa, 他10名
    • Journal Title

      Legal Medicine

      Volume: 12 Pages: 208-211

    • NAID

      10027576110

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Investigation of SNP haplotypes in the H19 imprinted gene.2009

    • Author(s)
      Nakayashiki N, Shimamoto K, Takamiya M, Hashiyada M, Yuasa I, Dewa K
    • Journal Title

      Forensic Science International : Genetics Supplement Series 2(1)

      Pages: 540-541

    • Related Report
      2010 Final Research Report
  • [Journal Article] HERC1 polymorphisms : populationspecific variations in haplotype composition.2009

    • Author(s)
      Yuasa I, Umetsu K, Nishimukai H, Fukumori Y, Harihara S, Saitou N, Jin F, Chattopadhyay PK, Henke L, Henke J
    • Journal Title

      Cell Biochemistry and Function 27(6)

      Pages: 402-405

    • Related Report
      2010 Final Research Report
  • [Journal Article] Caucasian-specific allele in non-synonymous single nucleotide polymorphisms of the gene encoding deoxyribonuclease I-like 3, potentially relevant to autoimmunity, produces an inactive enzyme.2009

    • Author(s)
      Ueki M, Takeshita H, Fujihara J, Iida R, Yuasa I, Kato H, Panduro A, Nakajima T, Kominato Y, Yasuda T
    • Journal Title

      Clinica Chimica Acta 407(1/2)

      Pages: 20-24

    • Related Report
      2010 Final Research Report
  • [Journal Article] Distinct carboxy- terminus of the B subunit for factor XIII in a population-associated major phenotype : the first case of complete allele-specific alternative splicing products in the coagulation and fibrinolytic systems.2009

    • Author(s)
      Iwata H, Kitano T, Umetsu K, Yuasa I, Yamazaki K, Kemkes-Matthes B, Ichinose A
    • Journal Title

      Journal of thrombosis and haemostasis 7(7)

      Pages: 1084-1091

    • Related Report
      2010 Final Research Report
  • [Journal Article] Allele frequencies and haplotypes for 28 Y-STRs in Ovambo population.2009

    • Author(s)
      Fujihara J, Yuasa I, Muro T, Iida R, Tsubota E, Nakamura H, Imamura Shinji, Yasuda T, Takeshita H
    • Journal Title

      Legal Medicine 11(4)

      Pages: 205-208

    • Related Report
      2010 Final Research Report
  • [Journal Article] Simultaneous genotyping of eleven non-synonymous SNPs in the four glutathione peroxidase genes using the multiplex single base extension method.2009

    • Author(s)
      Iida R, Tsubota E, Yuasa I, Takeshita H, Yasuda T
    • Journal Title

      Clinica Chimica Acta 402(1-2)

      Pages: 79-82

    • Related Report
      2010 Final Research Report
  • [Journal Article] Forensic species identification based on size variation of mitochondrial DNA hypervariable regions.2009

    • Author(s)
      Nakamura H, Muro T, Imamura S, Yuasa I
    • Journal Title

      International Journal of Legal Meidicine 123(2)

      Pages: 177-184

    • Related Report
      2010 Final Research Report
  • [Journal Article] HERC1 polymorphisms : population-specific variations in haplotype composition2009

    • Author(s)
      Isao Yuasa, 他9名
    • Journal Title

      Cell Biochemistry and Function 27

      Pages: 402-405

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Forensic species identification based on size variation of mitochondrial DNA hypervariable regions2009

    • Author(s)
      Hiroaki Nakamura, Isao Yuasa, 他2名
    • Journal Title

      International Journal of Legal Medicine 123

      Pages: 177-184

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Allele frequencies and haplotypes for 28 Y-STRs in Ovambo population2009

    • Author(s)
      Junko Fujihara, Isao Yuasa, 他7名
    • Journal Title

      Legal Medicine 11

      Pages: 205-208

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A decreasing dine of 374F allele frequencies in the skin pigmentationgene SLC45A2 from the north of West Europe to North Africa.2009

    • Author(s)
      Gerard Lucotte, 他2名Isao Yuasa
    • Journal Title

      Biochemical Genetics 47(印刷中)

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Molecular basis of complement factor I (CFI) polymorphism : One of two polymorphic suballeles responsible for CFI A is Japanese-specific.2008

    • Author(s)
      Yuasa I, Nakagawa M, Umetsu K, Harihara S, Matsusue A, Nishimukai H, Fukumori Y, Saitou N, Park KS, Jin F, Lucotte G, Chattopadhyay P, Henke L, Henke J
    • Journal Title

      Journal of Human Genetics 53(11-12)

      Pages: 1016-1021

    • NAID

      10025584984

    • Related Report
      2010 Final Research Report
  • [Journal Article] Haplotype analysis of seven Y-STRs (eleven loci) in two Japanese populations.2008

    • Author(s)
      Yuasa I, Irizawa Y, Nakamura H, Matusue A, Umetsu K
    • Journal Title

      Legal Medicine 10(6)

      Pages: 316-318

    • Related Report
      2010 Final Research Report
  • [Journal Article] Three single nucleotide polymorphisms leading to non-synonymous amino acid substitution in the human ribonuclease 2 and angiogenin genes exhibit markedky less genetic heterogeneity in six populations.2008

    • Author(s)
      Ueki M, Takeshita H, Fujihara J, Takatsuka H, Yuasa I, Iida R, Yasuda T
    • Journal Title

      Cell Biochemistry and Function 26(6)

      Pages: 718-722

    • Related Report
      2010 Final Research Report
  • [Journal Article] Population genetics of seventeen Y-chromosomal STR loci in Japanese.2008

    • Author(s)
      Hashiyada M, Umetsu K, Yuasa I, Tamura A, Matsusue A, Suzuki K, Kashimura S, Funayama M
    • Journal Title

      Forensic Science International : Genetics 2(4)

    • Related Report
      2010 Final Research Report
  • [Journal Article] Cutis laxa with frontoparietal cortical malformation : a novel type of congenital disorder of glycosylation.2008

    • Author(s)
      Okanishi T, Saito Y, Yuasa I, Miura M, Nagata I, Maegaki Y, Ohno K
    • Journal Title

      European Journal of Paediatric Neurology 12(3)

      Pages: 262-265

    • Related Report
      2010 Final Research Report
  • [Journal Article] Development of genotyping methods for single nucleotide polymorphism in the human pancreatic ribonuclease gene (RNASE1) and their application to population studies.2008

    • Author(s)
      Ueki M, Iida R, Fujihara J, Takeshita H, Yuasa I, Kominato Y, Yasuda T
    • Journal Title

      Biochemical Genetics 46(3/4)

      Pages: 145-153

    • Related Report
      2010 Final Research Report
  • [Journal Article] Allele frequencies of a SNP and a 27-bp deletion that are the determinant of earwax type in the ABCC11 gene.2008

    • Author(s)
      Kitano T, Yuasa I, Yamazaki K, Nakayashiki N, Miyoshi A, Park K-S, Umetsu K
    • Journal Title

      Legal Medicine 10(2)

      Pages: 113-114

    • Related Report
      2010 Final Research Report
  • [Journal Article] Haplotype analysis of seven Y-STRs (eleven loci) in two Japanese population.2008

    • Author(s)
      Isao Yuasa, Yoshito Irizawa, 他3名
    • Journal Title

      Legal Medicine 10

      Pages: 316-318

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Molcular basis of complement factor I (CFI)polymorphism : One oftwo polymorphic suballeles for CFI A is Japanese-specific.2008

    • Author(s)
      Isao Yuasa, Mayumi Nakagwa, 他12名
    • Journal Title

      Journal of Human Genetics 53

      Pages: 1016-1021

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Distribution of OCA2*481Thr and OCA2*615Arg, associated with hypopigmentation, in several additional populations.

    • Author(s)
      Yuasa I, Harihara S, Jin F, Nishimukai H, Fujihara J, Fukumori Y, Takeshita H, Umetsu K, Saitou N
    • Journal Title

      Legal Medicine (印刷中)

    • Related Report
      2010 Final Research Report
  • [Journal Article] Global genetic analysis of all single nucleotide polymorphisms in exons of the human deoxyribonuclease I-like 3 gene and their effect on its catalytic activity.

    • Author(s)
      Fujihara J, Yasuda T, Iida R, Kimura-Kataoka K, Soejima M, Koda Y, Kato H, Panduro A, Yuasa I, Takeshita H
    • Journal Title

      Electrophoresis (印刷中)

    • Related Report
      2010 Final Research Report
  • [Journal Article] Transferrin mutations at the glycosylation site complicate diagnosis of congenital disorders of glycosylation type I.

    • Author(s)
      Guillard M, Wada Y, Hansikova H, Yuasa I, Vesela K, Ondruskova N, Kadoya M, Janssen A, Van den Heuvel LP, Morava E, Zeman J, Wevers RA, Lefeber DJ.
    • Journal Title

      Journal of Inherited Metabolic Disease (印刷中)

    • Related Report
      2010 Final Research Report
  • [Presentation] 補体I因子のイントロン7にみられるSTRについて(2)2010

    • Author(s)
      湯浅勲、入澤淑人, 他4名
    • Organizer
      第94次日本法医学会学術全国集会
    • Place of Presentation
      東京タワーホール船堀
    • Year and Date
      2010-06-25
    • Related Report
      2010 Annual Research Report
  • [Presentation] Y染色体のハプロタイプグループを利用した民族推定法の開発2010

    • Author(s)
      室友紀、今村真二、渡部有希菜、中村博明、藤原純子、飯田礼子、安田年博、木村かおり、湯浅勲、副島美貴子、神田芳郎、竹下治男
    • Organizer
      第18回日本DNA多型学会
    • Place of Presentation
      三島
    • Related Report
      2010 Final Research Report
  • [Presentation] ATP6V0A2の変異による先天性グリコシル化異常症2010

    • Author(s)
      湯浅勲、遠藤実、入澤淑人、中川真由美、岡西徹、大野耕策
    • Organizer
      第18回日本DNA多型学会
    • Place of Presentation
      三島
    • Related Report
      2010 Final Research Report
  • [Presentation] 補体I因子のイントロン7にみられるSTRについて(2)2010

    • Author(s)
      湯浅勲、入澤淑人、梅津和夫、西向弘明、中屋敷徳、出羽厚二
    • Organizer
      第94次日本法医学会学術全国集会
    • Place of Presentation
      東京
    • Related Report
      2010 Final Research Report
  • [Presentation] ハンガリー人集団とロマ人集団におけるC7C106Rアリール及びC9R95Xアリールについて2010

    • Author(s)
      沖浦達幸、西向弘明、湯浅勲、福森泰雄、針原伸二、辻村隆介、織本千年、植田規史
    • Organizer
      第94次日本法医学会学術全国集会
    • Place of Presentation
      東京
    • Related Report
      2010 Final Research Report
  • [Presentation] 補体I因子のイントロン7にみられるSTRについて2009

    • Author(s)
      湯浅勲、入澤淑人、梅津和夫
    • Organizer
      第93次日本法医学会学術全国集会
    • Place of Presentation
      大阪千里ライフセンター
    • Year and Date
      2009-05-14
    • Related Report
      2009 Annual Research Report
  • [Presentation] CDGの検査で遭遇したトランスフェリンの二つの変異型2009

    • Author(s)
      湯浅勲、松尾宗明、副島美貴子、神田芳郎
    • Organizer
      第17回日本DNA多型学会
    • Place of Presentation
      久留米
    • Related Report
      2010 Final Research Report
  • [Presentation] A probable case of congenital disorder of glycosylation type Ib in Japan.2009

    • Author(s)
      Kudo T, Tsuchida M, Shinohara H, Fukushima H, Yuasa I, Ohno K, Sumazaki R
    • Organizer
      The 11th Congress of the Asia Pan-Pacific Society of Pediatric Gastroenterology, Hepatology, and Nutrition APPSPGHAN
    • Place of Presentation
      Seoul, Korea.
    • Related Report
      2010 Final Research Report
  • [Presentation] Investigation of SNP haplotypes in the H19 imprinted gene.2009

    • Author(s)
      Nakayashiki N, Shimamoto K, Takamiya M, Hashiyada M, Yuasa I, Dewa K
    • Organizer
      The 23rd World Congress of the International Society for Forensic Genetics.
    • Place of Presentation
      Buenos Aires, Argentina.
    • Related Report
      2010 Final Research Report
  • [Presentation] 補体I因子のイントロン7にみられるSTRについて2009

    • Author(s)
      湯浅勲、入澤淑人、梅津和夫
    • Organizer
      第93次日本法医学会総会
    • Place of Presentation
      大阪
    • Related Report
      2010 Final Research Report
  • [Presentation] OCA2遺伝子のSTR : F_<ST>の高いSNPの近くのSTRもF_<ST>が高い2008

    • Author(s)
      湯浅 勲, 入澤淑人, 梅津和夫
    • Organizer
      第92次日本法医学会総会
    • Place of Presentation
      長崎ブリックホール
    • Year and Date
      2008-04-24
    • Related Report
      2008 Annual Research Report
  • [Presentation] 補体I因子のCFI*Aは二つの集団特異的遺伝子からなる2008

    • Author(s)
      湯浅勲、入澤淑人、中川真由美、梅津和夫、針原伸二、松末綾、西向弘明、福森泰雄、齋藤成也
    • Organizer
      第17回日本DNA多型学会
    • Place of Presentation
      東京
    • Related Report
      2010 Final Research Report
  • [Presentation] APLP法によるYのハプログループ解析2008

    • Author(s)
      梅津和夫、湯浅勲、渡辺剛太郎、山崎健太郎
    • Organizer
      第92次日本法医学会総会
    • Place of Presentation
      長崎
    • Related Report
      2010 Final Research Report
  • [Presentation] OCA2遺伝子のSTR:Fstの高いSNPの近くのSTRもFstが高い2008

    • Author(s)
      湯浅勲、入澤淑人、梅津和夫
    • Organizer
      第92次日本法医学会総会
    • Place of Presentation
      長崎
    • Related Report
      2010 Final Research Report
  • [Book] 先天性グリコシル化異常症(小児科臨床ピクシス23:見逃せない先天代謝異常)(高柳正樹専門編集)2010

    • Author(s)
      平山良道、大野耕策、湯浅勲
    • Publisher
      中山書店、東京
    • Related Report
      2010 Final Research Report

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Published: 2008-04-01   Modified: 2016-04-21  

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