| Project/Area Number |
20590788
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Gastroenterology
|
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| Research Institution | Nagoya City University |
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Principal Investigator |
SUGAUCHI Fuminaka Nagoya City University, 大学院・医学研究科, 研究員 (20405161)
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|---|
| Co-Investigator(Kenkyū-buntansha) |
MIZOKAMI Masashi 名古屋市立大学, 大学院・医学研究科, 客員教授 (40166038)
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| Project Period (FY) |
2008 – 2010
|
| Project Status |
Completed (Fiscal Year 2010)
|
| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2008: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
|
|---|
| Keywords | B型肝炎ウイルス / 遺伝子型 / 肝癌 / ウイルス変異 / B型肝炎 / キメラマウス / 遺伝子変異 / 中和活性 / Vaccine / 複製モデル / recombination / コアプロモーター / 再活性化 / 系統樹 / 再活生化 |
|---|
| Research Abstract |
We investigated recombinant HBV genotype (r-HBV)using 807 full-genome sequences of HBV retrieved from DNA Data Bank. Twenty eight r-HBV were shown, 12 for A/D, 2 for A/C, 2 for/AE, 1 for A/G, 1 for A/B/C, 2 for B/C, 2 for C/D, 1 for C/F, 1 for C/G and 2 for U/G. Junction of r-HBV was more common at C terminus of S gene and core region.
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