Predictors for onset of acute myocardial infarction and cerebral infarction using biomarkers and imaging modalities
Project/Area Number |
20590833
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Circulatory organs internal medicine
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Research Institution | Osaka City University |
Principal Investigator |
EHARA Shoichi Osaka City University, 大学院・医学研究科, 講師 (90382150)
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Project Period (FY) |
2008 – 2010
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Project Status |
Completed (Fiscal Year 2010)
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Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2010: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2009: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2008: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
|
Keywords | 酸化LDL / ミエロペルオキシダーゼ / パラオキソナーゼ / プラーク / マルチスライスCT / 頸動脈エコー / MRI / 急性冠症候群 / 急性心筋梗塞 |
Research Abstract |
Acute myocardial infarction (AMI) and cerebral infarction (CI) are the leading causes of death in the individuals with atherosclerotic risk factors. As AMI or CI frequently occurs as the first symptom, screening of the patients with unstable plaque is important for prevention of the onset of AMI or CI. We suggested that combined assessment of biomarkers and cardiovascular imaging may be useful for screening patients with unstable plaques.
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Report
(4 results)
Research Products
(36 results)
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[Journal Article] Elevated levels of neopterin are associated with carotid plaques with complex morphology in patients with stable angina pectoris.2010
Author(s)
Sugioka K, Naruko T, Hozumi T, Nakagawa M, Kitabayashi C, Ikura Y, Shirai N, Matsumura Y, Ehara S, Ujino K, Itoh A, Haze K, Becker AE, Yoshiyama M, Ueda M
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Journal Title
Atherosclerosis 208
Pages: 524-530
Related Report
Peer Reviewed
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[Journal Article] Inadequate increase in the volume of major epicardial coronary arteries compared with that in left ventricular mass. Novel concept for characterization of coronary arteries using 64-slice computed tomography.2009
Author(s)
Ehara S, Okuyama T, Shirai N, Sugioka K, Oe H, Itoh T, Matsuoka T, Ikura Y, Ueda M, Naruko T, Hozumi T, Yoshiyama M.
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Journal Title
Circ J. 73
Pages: 1448-1453
NAID
Related Report
Peer Reviewed
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[Journal Article] Enhanced expression of haemoglobin scavenger receptor in accumulated macrophages of culprit lesions in acute coronary syndromes.2009
Author(s)
Yunoki K, Naruko T, Komatsu R, Ehara S, Shirai N, Sugioka K, Nakagawa M, Kitabayashi C, Ikura Y, Itoh A, Kusano K, Ohe T, Haze K, Becker AE, Ueda M
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Journal Title
Eur Heart J. 30
Pages: 1844-1852
Related Report
Peer Reviewed
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[Journal Article]2008
Author(s)
Okuyama T, Ehara S, Shirai N, Sugioka K, Ogawa K, Oe H, Kitamura H, Itoh T, Otani K, Matsuoka T, Inoue Y, Ueda M, Hozumi T, Yoshiyama M.
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Journal Title
J Cardiol 52
Pages: 276-284
Related Report
Peer Reviewed
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[Journal Article] Assessment of aortic atheromatous plaque and stiffness by 64-slice computed tomography is useful for identifying patients with coronary artery disease.2008
Author(s)
Okuyama T, Ehara S, Shirai N, Sugioka K, Yamashita H, Kataoka T, Naruko T, Itoh T, Otani K, Matsuoka T, Inoue Y, Ueda M, Yoshikawa J, Hozumi T, Yoshiyama M.
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Journal Title
Circ J. 72
Pages: 2021-2027
NAID
Related Report
Peer Reviewed
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[Journal Article] Small coronary calcium deposits and elevated plasma levels of oxidized low density lipoprotein are characteristic of acute myocardial infarction.2008
Author(s)
Ehara S, Naruko T, Shirai N, Itoh A, Hai E, Sugama Y, Ikura Y, Ohsawa M, Okuyama T, Shirai N, Yamashita H, Itabe H, Haze K, Yoshiyama M, Ueda M
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Journal Title
J Atheroscler Thromb. 15
Pages: 75-81
NAID
Related Report
Peer Reviewed
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[Journal Article] Morphological but not functional changes of the carotid artery are associated with the extent of coronary artery disease in patients with preserved left ventricular function.2008
Author(s)
Sugioka K, Hozumi T, Iwata S, Oe H, Okuyama T, Shirai N, Yamashita H, Ehara S, Kataoka T, Yoshikawa J, Ueda M, Yoshiyama M.
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Journal Title
Stroke 39
Pages: 1597-1599
Related Report
Peer Reviewed
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[Presentation] Myeloperoxidase are associated with low density lipoprotein oxidation and unstable coronary syndrome in human.2008
Author(s)
Ehara S, Naruko T, Nakagawa M, Kitabayashi C, Shirai N, Sugioka K, Oe H, Okuyama T, Hozumi T, Haze K, Itabe H, Yoshiyama M, Ueda M.
Organizer
第72回日本循環器学会
Place of Presentation
福岡
Year and Date
2008-03-28
Related Report