Investigation of a novel a cardiovascular inflammation marker, Pentraxin 3
| Project/Area Number |
20590840
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Circulatory organs internal medicine
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| Research Institution | Juntendo University |
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Principal Investigator |
INOUE Kenji (INOUE Kenii) 順天堂大学, 医学部, 准教授 (80317388)
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| Co-Investigator(Kenkyū-buntansha) |
SUWA Satoru 順天堂大学, 医学部, 先任准教授 (90226613)
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| Project Period (FY) |
2008 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2011: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2010: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2009: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2008: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
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| Keywords | バイオマーカー / 急性冠症候群 / 胸痛 / 睡眠時無呼吸症候群 / 臨床 / 動脈硬化 |
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| Research Abstract |
In Japan as well as industry countries, the mortality caused by cardiovascular disease is worst. General practitioners are expected to make a diagnosis of such disease although they are not cardiologist. ECG or UCG are useful tools to make a diagnosis for such disease, but still, they require specific technique to make a diagnosis. We established a novel cardiovascular marker, Pentraxin 3 (PTX3). Only 0.1mL blood sample reflect the status of the inflammation of vascular. In this study, we have reported that PTX3 was a useful marker to predict the prognosis for patients with acute coronary syndrome, or sleep apnea syndrome.
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Report
(6 results)
Research Products
(39 results)
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[Journal Article] Plasma Pentraxin3 and Arterial Stiffness in Men With Obstructive Sleep Apnea.2010
Author(s)
Kasai T, Inoue K, Kumagai T, Kato M, Kawana F, Sagara M, Ishiwata S, Ohno M, Yamaguchi T, Momomura SI, Narui K.
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Journal Title
Related Report
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[Journal Article] Plasma pentraxin 3 and arterial stiffness in men with obstructive sleep apnea2010
Author(s)
Kasai T, Inoue K, Kumagai T, Kato M, Kawana F, Sagara M, Iwashita S, Ohono M, Yamaguchi T, Momomura S, Narui K
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Journal Title
American Journal of Hypertension. 2010
Volume: (in press)
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Peer Reviewed
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[Presentation] European society of cardiology congress2008
Author(s)
Inoue K, Suwa S, Okazaki S, Sagara M, Salvchenko A, Ito S, Naito M, Diada H
Organizer
The involvement of neutrophils in the increased plasma pentraxin3 levels in patients with acute coronary syndrome.
Place of Presentation
Kodama
Related Report
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[Patent(Industrial Property Rights)] 全身性炎症反応症候群の治療又は予防剤2012
Inventor(s)
浜窪 隆雄,津本 浩平,太期 健二,井上 健司,山口 尚敬,水内 素晶
Industrial Property Rights Holder
浜窪 隆雄,津本 浩平,太期 健二,井上 健司,山口 尚敬,水内 素晶
Filing Date
2012-06-22
Related Report
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