| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2010: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2008: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Research Abstract |
In this study, serum hepcidin-25, which is the regulator of the iron-metabolism, has been measured by mass spectrometry, and has became a molecular biomarker of erythropoietic disorders including renal anemia、iron overload and inflammation. The characteristics of iron-metabolism are to recycle iron in the closed system without an active iron-excretion system, and to keep the concentration of the serum iron. This is managed with the feed back mechanism based on the transferring receptor2-hepcidin-ferroportin system.
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