The gender difference in the mechanisms that control glomerular hemodynamics.
| Project/Area Number |
20590968
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Kidney internal medicine
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| Research Institution | Kinki University |
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Principal Investigator |
ARIMA Shuji Kinki University, 医学部, 准教授 (60323010)
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| Co-Investigator(Kenkyū-buntansha) |
TANIYAMA Yoshihiro 近畿大学, 医学部, 講師 (70441079)
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| Project Period (FY) |
2008 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2009: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2008: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
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| Keywords | 輸出入細動脈 / 性差 / 血管内皮機能 / 性ホルモン / 糸球体血行動態 / 老化 / 慢性腎臓病 |
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| Research Abstract |
We found neither gender difference in the control mechanisms of glomerular hemodynamics nor in the vascular reactivity of renal arterioles. In addition, at least under our experimental conditions any sexual hormone did not exert significant vascular actions on renal arterioles. .
In the present study, we could not establish but somewhat develop an experimental system to study the possible gender differences in renal medullary blood flow. We also tried to develop a culture system of vascular smooth muscle cells and endothelial cells of renal arterioles to study the detail cellular mechanisms underlying the physiological and/or pathophysiological glomerular hemodynamics.
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Report
(4 results)
Research Products
(6 results)
