• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

The gender difference in the mechanisms that control glomerular hemodynamics.

Research Project

Project/Area Number 20590968
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Kidney internal medicine
Research InstitutionKinki University

Principal Investigator

ARIMA Shuji  Kinki University, 医学部, 准教授 (60323010)

Co-Investigator(Kenkyū-buntansha) TANIYAMA Yoshihiro  近畿大学, 医学部, 講師 (70441079)
Project Period (FY) 2008 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2009: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2008: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Keywords輸出入細動脈 / 性差 / 血管内皮機能 / 性ホルモン / 糸球体血行動態 / 老化 / 慢性腎臓病
Research Abstract

We found neither gender difference in the control mechanisms of glomerular hemodynamics nor in the vascular reactivity of renal arterioles. In addition, at least under our experimental conditions any sexual hormone did not exert significant vascular actions on renal arterioles. .
In the present study, we could not establish but somewhat develop an experimental system to study the possible gender differences in renal medullary blood flow. We also tried to develop a culture system of vascular smooth muscle cells and endothelial cells of renal arterioles to study the detail cellular mechanisms underlying the physiological and/or pathophysiological glomerular hemodynamics.

Report

(4 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (6 results)

All 2010 2009

All Journal Article (3 results) (of which Peer Reviewed: 3 results) Presentation (3 results)

  • [Journal Article] Decreased expression of catechol-O- methyltransferase in the renal cortex of malignant spontaneously hypertensive rats.2009

    • Author(s)
      Ooshima K, Ozaki S, Tabuch M, Higashino H, Honda E, Park AM, Arima S, Munakata H
    • Journal Title

      Tohoku J Exp Med. 219

      Pages: 331-336

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Poldip 2, a novel regulator of Nox4 and cytoskeletal integrity in vascular smooth muscle cells.2009

    • Author(s)
      Lyle AN, Deshpande NN, Taniyama Y, Seidel-Rogol B, Pounkova L, Du P, Papaharalambus C, Lassegue B, Griendling KK
    • Journal Title

      Circ Res 105

      Pages: 249-259

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Decreased expression of catechol-O-methyltransferase in the renal cortex of malignant spontaneously hypertensive rats2009

    • Author(s)
      Ooshima K, 他5名
    • Journal Title

      Tohoku J Exp Med 219

      Pages: 331-336

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Presentation] Malignant Hypertension モデルmSHR-spラットにおける腎での臓器障害と酸化ストレス・小胞体ストレスとの関与、機序の検討2010

    • Author(s)
      中谷嘉寿、谷山佳弘、高見勝弘、有馬秀二
    • Organizer
      第33回日本高血圧学会総会
    • Place of Presentation
      福岡
    • Year and Date
      2010-10-16
    • Related Report
      2010 Final Research Report
  • [Presentation] Poldip2の糖尿病性腎症(DN)における病態生理学的意義に関する検討2010

    • Author(s)
      中谷嘉寿、谷山佳弘、岸本和也、嶋津秀紀、金籐秀明、松久宗英、Griendling KK、木下浩二、船内正憲、有馬秀二
    • Organizer
      第53回日本腎臓学会総会
    • Place of Presentation
      神戸
    • Year and Date
      2010-06-16
    • Related Report
      2010 Final Research Report
  • [Presentation] Poldip2糖尿病性腎症における病態生理学的意義に関する検言2010

    • Author(s)
      中谷嘉寿、有馬秀二, 他8名
    • Organizer
      第53回日本腎臓学会総会
    • Place of Presentation
      神戸市
    • Year and Date
      2010-06-16
    • Related Report
      2010 Annual Research Report

URL: 

Published: 2008-04-01   Modified: 2016-04-21  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi