| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2009: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2008: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Research Abstract |
In our 204 consecutive autopsied cases, there were close relationship between α-synuclein pathology in dorsal vagal nuculei and the decrease of tyrosine hydroxylase immunorectivites in cardiac sympathetic nerves. We reported FUS pathology in various amyotrophic lateral sclerosis (ALS) types, clinical and neuropathological findings of Japanese familial ALS patients with a novel TDP-43 A315E mutation, presence of several peripherin-positive Bunina bodies, and appearance of optineurin not only in ALS but also in many neurodegenerative conditions.
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