• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

A study for urokinase activating system during muscle regeneration

Research Project

Project/Area Number 20591028
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Neurology
Research InstitutionWakayama Medical University

Principal Investigator

MURATA Kenya  Wakayama Medical University, 医学部, 講師 (90264853)

Co-Investigator(Kenkyū-buntansha) HIWATANI Yasuhiro  和歌山県立医科大学, 医学部, 助教 (40405452)
MIWA Hideto  和歌山県立医科大学, 医学部, 准教授 (50231626)
KONDO Tomoyoshi  和歌山県立医科大学, 医学部, 教授 (50103891)
KAJIMOTO Yoshinori  和歌山県立医科大学, 医学部, 助教 (20398457)
KODAMA Rieko  和歌山県立医科大学, 医学部, 学内助教 (20336887)
Project Period (FY) 2008 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2009: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2008: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywords骨格筋再生 / 筋疾患 / ウロキナーゼ / ウロキナーゼプラスミノーゲンアクチベーター / ウロキナーゼアクチベーター受容体 / Cardiotoxin(CTX)損傷モデル / ウロキナーゼプラスミノーゲンアクチベータ受容体 / cardiotoxin(CTX)損傷モデル
Research Abstract

We performed immunohistological study for the distribution of urokinase, urokinase-plasminogen receptor and plasminogen receptor using muscle biopsy specimens of polymyositis and dermatomyositis.
Urokinase, urokinase-plasminogen receptor and plasminogen receptor were expressed at the sarcolemma and cytoplasm of muscle fibers.
These observations suggest that plasminogen activating system play an important role of muscle fiber regeneration in inflammatory myopathy.

Report

(4 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (33 results)

All 2010 2009 2008

All Journal Article (18 results) (of which Peer Reviewed: 15 results) Presentation (14 results) Book (1 results)

  • [Journal Article] Polyneuritis cranialis caused by varicella zoster virus in the absence of rash.2010

    • Author(s)
      村田顕也, 三輪英人, 近藤智善
    • Journal Title

      Neurology 74

      Pages: 85-86

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] A dysphagia study in patients with inclusion body myositis.2010

    • Author(s)
      Murata K, Kouda K, Miwa H, Kondo T
    • Journal Title

      Neuromuscular Disorders. 20

      Pages: 631-632

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] 紀伊半島南部地域における筋萎縮性側索硬化症-和歌山県内多発地域における最近の発症率の推移と臨床像の変化.2010

    • Author(s)
      紀平為子, 吉田宗平, 村田顕也
    • Journal Title

      Brain andnerve 62

      Pages: 72-80

    • NAID

      40016966009

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] パーキンソン病患者の脊柱起立筋の臨床病理学的検討2010

    • Author(s)
      村田顕也, 三輪英人, 近藤智善
    • Journal Title

      脳21 13

      Pages: 347-347

    • Related Report
      2010 Final Research Report
  • [Journal Article] 脊髄腫瘍と鑑別を要したアトピー性脊髄炎の1 例2010

    • Author(s)
      寺下浩平, 南出晃人, 吉田宗人, 村田顕也, 近藤智善
    • Journal Title

      臨床整形外科 45

      Pages: 665-669

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] A Dysphagia study in patients with Inclusion body Myositis2010

    • Author(s)
      K Murata, H Miwa, T Kondo
    • Journal Title

      Neuromuscular Disorders

      Volume: 20 Pages: 631-632

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Changes in the incidence and clinical features of ALS in the Koza, Kozagawa, and Kushimoto area of the Kii Peninsula-from the 1960s to the 2000s (follow-up study)2010

    • Author(s)
      T Kihira,K Murata, T Kondo
    • Journal Title

      Brain Nerve

      Volume: 62 Pages: 72-80

    • NAID

      40016966009

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Polyneuritis cranialis caused by varicella zoster virus in the absence of rash2010

    • Author(s)
      K Murata, H Miwa, T Kondo
    • Journal Title

      Neurology 74

      Pages: 85-86

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Changes in the incidence and clinical features of ALS in the Koza, Kozagawa, and Kushimoto area of the Kii Peninsula-from the 1960s to the 2000s(follow-up study)2010

    • Author(s)
      T Kihira, K Murata, T Kondo
    • Journal Title

      Brain Nerve 62

      Pages: 72-80

    • NAID

      40016966009

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Analysis of the plasminogen activating system during muscle fiber regeneration in cardiotoxin injured muscle fibers.2009

    • Author(s)
      村田顕也, 三輪英人, 近藤智善
    • Journal Title

      Neurology 72

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Paraspinal muscle changes in parkinson's disease patients with scoliosis.2009

    • Author(s)
      Murata K-Y, Kajimoto Y, Miwa H, Kondo T
    • Journal Title

      Mov Disord 24

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Cardiotoxin 損傷モデルマウスの筋再生過程におけるplasminogen activatingsystemの検討2009

    • Author(s)
      村田顕也, 三輪英人, 近藤智善
    • Journal Title

      神経治療学 26

      Pages: 337-337

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] 筋萎縮性側索硬化症患者における経皮内視鏡的胃瘻造設術の検討2009

    • Author(s)
      村田顕也, 三輪英人, 近藤智善
    • Journal Title

      The Japanese Journal of Rehabilitation Medicine. 46

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Analysisi of the plasminogen activating system during muscle fiber regeneration in inflammatory myopathy.2008

    • Author(s)
      Murata K, Kodama R, Miwa H, Kondo T
    • Journal Title

      Neurology 70

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] 脊髄小脳変性症の摂食・嚥下機能と訓練方法(脊髄小脳変性症のリハビリテーション)2008

    • Author(s)
      牧野直弘, 田島文博, 村田顕也
    • Journal Title

      Monthly book medicalrehabilitation 93

      Pages: 31-36

    • NAID

      40016136472

    • Related Report
      2010 Final Research Report
  • [Journal Article] 封入体筋炎の嚥下障害の検討2008

    • Author(s)
      村田顕也, 後藤正樹
    • Journal Title

      The Japanese Journal of Rehabilitation Medicine. 45

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] 炎症性筋疾患の筋再生過程におけるplasminogen activating systemの検討2008

    • Author(s)
      村田顕也, 三輪英人, 近藤智善
    • Journal Title

      神経治療学 25

      Pages: 302-302

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] 脊髄小脳変性症の摂食・嚥下機能の訓練方法2008

    • Author(s)
      牧野直弘, 田島文博, 村田顕也
    • Journal Title

      Medical Rehabilitation 93

      Pages: 31-36

    • Related Report
      2008 Annual Research Report
  • [Presentation] A Dysphagia study in patients with Inclusion body Myositis2010

    • Author(s)
      K Murata, K Kouda, T Kondo
    • Organizer
      15th International Congress of the World Muscle Society
    • Place of Presentation
      Kumamoto, Japan(招待講演)
    • Related Report
      2010 Annual Research Report
  • [Presentation] 嚥下障害を呈する封入体筋炎の症例2010

    • Author(s)
      村田顕也, 三輪英人, 近藤智善
    • Organizer
      第51回日本神経学会総会
    • Place of Presentation
      東京
    • Related Report
      2010 Annual Research Report
  • [Presentation] 封入体筋炎の嚥下機能の評価2010

    • Author(s)
      村田顕也, 三輪英人, 近藤智善
    • Organizer
      第28回日本神経学会総会
    • Place of Presentation
      横浜
    • Related Report
      2010 Annual Research Report
  • [Presentation] Dysphagia in patients with Inclusion body Myositis2010

    • Author(s)
      K Murata, K Kouda, T Kondo
    • Organizer
      The 9th Asian-Oceanian Myology Center(AOMC)Scientific Meeting(招待講演)
    • Place of Presentation
      Seoul, Korea
    • Related Report
      2009 Annual Research Report
  • [Presentation] Analysis of the plasminogen activating system during muscle fiber regeneration in cardiotoxin-injured muscle fibers2009

    • Author(s)
      K Murata, K Kouda, T Kondo
    • Organizer
      American Academy of Neurology 61st Annual Meetimg
    • Place of Presentation
      Seattle, USA
    • Year and Date
      2009-04-28
    • Related Report
      2009 Annual Research Report
  • [Presentation] Analysis of plasminogen activating system during muscle regeneration in cardiotoxin-injured muscle fibers.2009

    • Author(s)
      Murata K, Miwa H, Kondo T
    • Organizer
      American Academy of Neurology 61^<st> Annual meeting
    • Place of Presentation
      Seattle
    • Year and Date
      2009-04-25
    • Related Report
      2010 Final Research Report
  • [Presentation] Cardiotoxin損傷モデルマウスの筋再生課程におけるpalasminoge activating systemの検討2009

    • Author(s)
      村田顕也
    • Organizer
      第27回日本神経治療学会総会
    • Place of Presentation
      熊本
    • Related Report
      2010 Final Research Report
  • [Presentation] Paraspinal muscle changes in Parkinson's disease patients with scoliosis MDS2009

    • Author(s)
      Murata K, Kajimoto Y, Miwa H, Kondo T
    • Organizer
      13^<th> International congress
    • Place of Presentation
      Paris
    • Related Report
      2010 Final Research Report
  • [Presentation] 炎症性筋疾患におけるpalasminogen activating systemの検討2009

    • Author(s)
      村田顕也
    • Organizer
      第50回日本神経学会総会
    • Place of Presentation
      仙台
    • Related Report
      2010 Final Research Report
  • [Presentation] 炎症性筋疾患における plasminogen activating system の検討2009

    • Author(s)
      村田顕也, 三輪英人, 松井真, 近藤智善
    • Organizer
      第50回日本神経学会総会
    • Place of Presentation
      仙台
    • Related Report
      2009 Annual Research Report
  • [Presentation] 炎症性筋疾患の筋再生過程におけるplasminogen activating system の検討2008

    • Author(s)
      村田顕也, 三輪英人, 近藤智善
    • Organizer
      日本神経治療学会
    • Place of Presentation
      横浜
    • Year and Date
      2008-06-26
    • Related Report
      2008 Annual Research Report
  • [Presentation] 封入体筋炎の嚥下障害の検討2008

    • Author(s)
      村田顕也, 後藤正樹, 三輪英人, 近藤智善
    • Organizer
      日本リハビリテーション医学会
    • Place of Presentation
      横浜
    • Year and Date
      2008-06-03
    • Related Report
      2008 Annual Research Report
  • [Presentation] Analysis of the plasminogen activating system during muscle fiber regeneration in inflammatory myopathy2008

    • Author(s)
      Kenya Murata, Hideto Miwa, Tomoyoshi Kondo
    • Organizer
      American Academy of Neurology 60^<th> Annual Meeting
    • Place of Presentation
      Chicago, USA
    • Year and Date
      2008-04-13
    • Related Report
      2008 Annual Research Report
  • [Presentation] Analysis of plasminogen activating system during muscle regeneration in inflammatory myopathy.2008

    • Author(s)
      Murata K, Kodama R, Miwa H, Kondo T
    • Organizer
      American Academy of Neurology 60^<th> Annual meeting
    • Place of Presentation
      Chicago
    • Related Report
      2010 Final Research Report
  • [Book] 脳神経外科医のための脊椎脊髄疾患診断と治療ガイド2010

    • Author(s)
      村田顕也
    • Total Pages
      340
    • Publisher
      メジカルビュー社
    • Related Report
      2010 Annual Research Report

URL: 

Published: 2008-04-01   Modified: 2016-04-21  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi