Morphological analysis of neural connections of the presubicular and parasubicular areas.
Project/Area Number |
20591032
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Neurology
|
Research Institution | Tokyo Women's Medical University |
Principal Investigator |
HONDA Yoshiko Tokyo Women's Medical University, 医学部, 講師 (40287313)
|
Project Period (FY) |
2008 – 2010
|
Project Status |
Completed (Fiscal Year 2010)
|
Budget Amount *help |
¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2010: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2009: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2008: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
|
Keywords | 臨床神経形態学 / 記憶 / 前海馬台 / ウイルスベクター / GFP / 単一神経細胞 / 軸索 / 内側嗅内野 / 脳梁膨大後部皮質 |
Research Abstract |
The parahippocampal regions including the presubiculum are known to be responsible for processing and integrating spatial representation information. However, details of input- and output connections of these areas are still unknown. To understand better the functional roles played by the presubiculum, we studied the axonal morphology of single layer V neurons of the presubiculum, which were visualized in the rat with a viral vector expressing membrane-targeted green fluorescent protein. We found that individual layer V neurons provide axonal branches to one or two cortical areas with several recurrent collaterals to the presubiculum itself. Our data demonstrated that there are at least six types of neurons which have different patterns of axonal collateralization in layer V of the rat presubiculum.
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Report
(4 results)
Research Products
(9 results)