| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2010: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2009: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2008: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Research Abstract |
Insulin dependent glucose transport is one of the most important steps for insulin action in peripheral tissues. However, the precise mechanism how insulin regulates glucose transport is still unclear. In this project, CLIP170 was identified as a microtubule plus -end protein by MALDI-TOF MS analysis. This protein had a essential roles on GLUT4-vesicle translocation to the plasma membrane and glucose uptake in response to insulin stimulation.
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