| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2010: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2009: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2008: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Research Abstract |
Vitamin D deficiency resulting in hypocalcemic seizures or rickets in children is increasing worldwide, due to an insufficient intake of vitamin D and a lack of sunshine exposure. Since the prevalence of vitamin D deficiency is low compared to the large number of breastfed children with low serum levels of 25OHD, we speculated that some genetic predisposition may be concerned with the onset of vitamin D deficiency. In this study, we analyzed polymorphisms in vitamin D related genes in patients with vitamin D deficiency and controls in Japan. We found differences in the polymorphisms, suggesting that genetic factors may predispose to vitamin D deficiency to some extent.
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