| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2010: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2008: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Research Abstract |
We tried to reveal cytokines action on very early stage of Kawasaki Disease (KD) by analyzing gene profiling in thrombocyte of Kawasaki disease patients. On very early stage of KD, the genes involving innate immunity and complement activation, such as Interleukin-1, Interleukin-18 and C1q, were significantly expressed. However, we could not detect complement activation in the serum of KD patients on admission. Analysis of Single Nucleotide Polymorphism about the genes involving innate immunity is on-going.
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