| Project/Area Number |
20591296
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Embryonic/Neonatal medicine
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| Research Institution | Nagoya University |
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Principal Investigator |
HAYAKAWA Masahiro Nagoya University, 医学部附属病院, 講師 (40343206)
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| Co-Investigator(Kenkyū-buntansha) |
OKUMURA Akihisa 順天堂大学, 医学部, 准教授 (60303624)
SATO Yoshiaki 名古屋大学, 医学部附属病院, 助教 (30435862)
NAKAYAMA Atsushi 名古屋大学, 医学部附属病院, 助教 (30452197)
伊東 真隆 名古屋大学, 医学部附属病院, 病院助手 (40464143)
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| Project Period (FY) |
2008 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2008: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | 胎児発育不全 / 中枢神経障害 / 栄養管理 / 合成トロンボキサンA2 / メタボリック症候群 / 中枢神経障 |
|---|
| Research Abstract |
Fetal growth restriction (FGR) is one of the causes of small-for-gestational age (SGA). SGA is high risk of neurological squelae in later life. Neonatologists have introduced aggressive nutrition to SGA infants in order to prevent from neurological sequelae. However, it is suggested that such nutritional strategies might produce metabolic syndrome in later life. In this study, postnatal nutritional intervention might induce metabolic syndrome in later life and alternation of lipid in brain. It is suggested that optimal nutritional strategies might be important in SGA infants in order to decrease morbidity.
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