Arousal response and autonomic control in infants with future sudden death

• Project/Area Number: 20591302
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Embryonic/Neonatal medicine
• Research Institution: Nagoya City University
• Principal Investigator: KATO Ineko Nagoya City University, 大学院・医学研究科, 准教授 (00305541)
• Co-Investigator(Kenkyū-buntansha): TOGARI Hajime 名古屋市立大学, 大学院・医学研究科 (50106233)
• Research Collaborator: PATRICIA Franco リヨン女性母体小児病院, Pediatric Sleep Unit, 主任 ; JOSE Groswasser ブリュッセル自由大学附属ファビオラ女王記念小児病院, Pediatric Sleep Unit, 主任 ; SONIA Scaillet ブリュッセル自由大学附属ファビオラ女王記念小児病院, Pediatric Sleep Unit, 主任
• Project Period (FY): 2008 – 2010
• Project Status: Completed (Fiscal Year 2010)
• Budget Amount: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000); Fiscal Year 2010: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000); Fiscal Year 2009: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000); Fiscal Year 2008: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
• Keywords: 乳幼児突然死症候群 / SIDS / 覚醒反応 / 睡眠 / 自律神経系

Research Abstract

Sudden Infant Death Syndrome (SIDS) is a leading cause of infants under one year of age. In this study, heart rate spectral analysis and detrended fluctuation analysis (DFA) were made in infants with sudden unexpected death and control infants. DFAα_1 was decreased in SIDS cases compared with control infants. This result reflects abnormal control of autonomic nervous system in SIDS cases.

Research Products

• [Presentation] SIDS症例における非線形解析を用いた心拍変動解析 (2011)
  • Author(s): 加藤稲子、早野順一郎、Scaillet S, Groswasser J, Franco P,戸苅創
  • Organizer: 日本SIDS・乳幼児突然死予防学会
  • Place of Presentation: ビッグハート出雲(出雲、島根)
  • Year and Date: 2011-03-04
• [Presentation] SIDS症例における非線形解析を用いた心拍変動解析 (2011)
  • Author(s): 加藤稲子、早野順一郎、Fanco P、Scaillet S、Groswasser J、戸苅創
  • Organizer: 日本SIDS・乳幼児突然死予防学会
  • Place of Presentation: 出雲、島根
• [Presentation] Nonlinear Heart Rate Dynamics and Heart Rate Variability in Infants with Future Sudden Death. (2010)
  • Author(s): Kato I, Hayano J, Fanco P, Scaillet S, Groswasser J, Togari H.
  • Organizer: Congress of the International Pediatric Sleep Association joint meeting with Pediatric Sleep Medicine Conference.
  • Place of Presentation: Rome, Italy
• [Presentation] Nonlinear Heart Rate Dynamics and Heart Rate Variability in Infants with Future Sudden Death (2010)
  • Author(s): Kato I, Hayano J, Scaillet S, Groswasser J, Franco P, Togari H.
  • Organizer: Congress of the International Pediatric Sleep Association joint meeting with Pediatric Sleep Medicine Conference
  • Place of Presentation: Hotel Nazionale(Rome, Italy)