• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Research of the role of tenascin C in coronary development

Research Project

Project/Area Number 20591310
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Embryonic/Neonatal medicine
Research InstitutionTokyo Women's Medical University

Principal Investigator

TOMITA Sachiko  Tokyo Women's Medical University, 医学部, 助教 (40231451)

Co-Investigator(Kenkyū-buntansha) YOSHIDA Kyoko  三重大学, 医学研究科, 准教授 (00242967)
Project Period (FY) 2008 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2008: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywords冠動脈 / 形態形成 / テネイシンC / 発生 / 血管形成 / 発達 / テネイシン
Research Abstract

Cells destined to form the coronary vasculature which supply oxygen and nutrients to the heart are thought to originate in the proepicardium. We examined an extracellular glycoprotein tenascin C in formation of the coronary stem and epithelial mesenchymal transformation of proepicardium-derived cells. Expression of tenascin C was seen in developing coronary stems and coronary smooth muscle cells. It is suggested that tenascin C facilitates the differentiation of proepicardium-derived cells into myofibroblast/smooth muscle cells, however, not induce the invasion/migration of the cells in vitro system.

Report

(4 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (94 results)

All 2011 2010 2009 2008 Other

All Journal Article (33 results) (of which Peer Reviewed: 27 results) Presentation (56 results) Book (5 results)

  • [Journal Article] Effects of transforming growth factor-b3 and matrix metalloproteinase-3 on the pathogenesis of chronic mitral valvular disease in dogs2011

    • Author(s)
      Obayashi K, Miyagawa-Tomita S, Matsumoto H, Koyama H, Nakanishi T,Hirose H
    • Journal Title

      Am J Vet Res 72

      Pages: 194-202

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Tenascin C induces epithelial-mesenchymal transition-like change accompanied by SRC activation and focal adhesion kinase phosphorylation in human breast cancer cells2011

    • Author(s)
      Nagaharu K, Zhang X, Yoshida T, Katoh, D, Hanamura, N, Kozuka Y, Ogawa T, Shiraishi T, Imanaka-Yoshida K
    • Journal Title

      Am J Pathol 178

      Pages: 754-63

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Developmental defects of coronary vasculature in rat embryos administered bis-diamine2011

    • Author(s)
      Hanato T, Nakagawa M, Okamoto N, Nishijima S, Fujino H, Shimada M, Takeuchi Y, Imanaka-Yoshida K
    • Journal Title

      Birth Defects Res B Dev Reprod Toxicol 92

      Pages: 10-6

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] 心筋炎2011

    • Author(s)
      今中恭子
    • Journal Title

      病理と臨床 29

      Pages: 126-131

    • Related Report
      2010 Final Research Report
  • [Journal Article] Effects of transforming growth factor-beta3 and matrix metalloproteinase-3 on the pathogenesis of chronic mitral valvular disease in dogs.2011

    • Author(s)
      Obayashi K, Miyagawa-Tomita S, Matsumoto H, Koyama H, Nakanishi T, Hirose H.
    • Journal Title

      American Journal of Veterinary Research

      Volume: 72 Pages: 194-202

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Tenascin C induces epithelial-mesenchymal transition-like change accompanied by SRC activation and focal adhesion kinase phosphorylation in human breast cancer cells.2011

    • Author(s)
      Nagaharu K, Zhang X, Yoshida T, Katoh D, Hanamura N, Kozuka Y, Ogawa T, Shiraishi T, Imanaka-Yoshida, K.
    • Journal Title

      Am J Pathol

      Volume: 178 Pages: 754-763

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Developmental defects of coronary vasculature in rat embryos administered bis-diamine.2011

    • Author(s)
      Hanato T, Nakagawa M, Okamoto N, Nishijima S, Fujino H, Shimada M, Takeuchi Y, Imanaka-Yoshida K.
    • Journal Title

      Birth Defects Res B Dev Reprod Toxicol

      Volume: 92 Pages: 10-16

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 心筋炎2011

    • Author(s)
      今中恭子
    • Journal Title

      病理と臨床

      Volume: 29 Pages: 126-131

    • Related Report
      2010 Annual Research Report
  • [Journal Article] Role of mesodermal FGF8 and FGF10 overlaps in the development of the arterial pole of the heart and pharyngeal arch arteries2010

    • Author(s)
      Watanabe Y, Miyagawa-Tomita S, Vincent SD, Kelly RG, Moon AM, Buckingham ME
    • Journal Title

      Circ Res 106

      Pages: 495-503

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Endothelin receptor Type A expression defines a distinct cardiac subdomain within the heart field and later implicated in chamber myocardium formation2010

    • Author(s)
      Asai R, Kurihara Y, Fujisawa K, Sato T, Kawamura Y, Kokubo H, Tonami K, Nishiyama K, Uchijima Y, Miyagawa-Tomita S, Kurihara H
    • Journal Title

      Development 137

      Pages: 3823-3833

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Tenascin-C enhances crosstalk signaling of integrin alphavbeta3/PDGFR-beta complex by SRC recruitment promoting PDGF-induced proliferation and migration in smooth muscle cells2010

    • Author(s)
      Ishigaki T, Imanaka-Yoshida K, Shimojo N, Matsushima S, Taki W, Yoshida T
    • Journal Title

      J Cell Physiol 28(Epub head of prints)

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Dynamic expression of tenascin-C after myocardial ischemia and reperfusion : assessment by 125I-anti-tenascin-C antibody imaging2010

    • Author(s)
      Taki J, Inaki A, Wakabayashi H, Imanaka-Yoshida K, Ogawa K, Hiroe M, Shiba K, Yoshida T, Kinuya S
    • Journal Title

      J Nucl Med 51

      Pages: 1116-22

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] テネイシンCの役割2010

    • Author(s)
      今中恭子
    • Journal Title

      総合臨床 59

      Pages: 1725-1728

    • Related Report
      2010 Final Research Report
  • [Journal Article] Tenascin-C may aggravate left ventricular remodeling and function after myocardial infarction in mice2010

    • Author(s)
      Nishioka T, Onishi K, Shimojo N, Nagano Y, Matsusaka H, Ikeuchi M, Ide T, Tsutsui H, Hiroe M, Yoshida T, Imanaka-Yoshida K
    • Journal Title

      Am J Physiol Heart Circ Physiol 298

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Role of mesodermal FGF8 and FGF10 overlaps in the development of the arterial pole of the heart and pharyngeal arch arteries.2010

    • Author(s)
      Watanabe Y, Miyagawa-Tomita S, Vincent SD, Kelly RG, Moon AM, Buckingham ME.
    • Journal Title

      Circulation Research

      Volume: 106 Pages: 495-503

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Endothelin receptor Type A expression defines a distinct cardiac sub-domain within the heart field and later implicated in chamber myocardium formation.2010

    • Author(s)
      Asai R, Kurihara Y, Fujisawa K Sato T, Kawamura Y, Kokubo H, Tonami K, Nishiyama K, Uchijima Y, Miyagawa-Tomita S, Kurihara H.
    • Journal Title

      Development

      Volume: 137 Pages: 3823-3833

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Tenascin-C enhances crosstalk signaling of integrin alphavbeta3/PDGFR-beta complex by SRC recruitment promoting PDGF-induced proliferation and migration in smooth muscle cells.2010

    • Author(s)
      Ishigaki, T, Imanaka-Yoshida K, Shimojo N, Matsushima S, Taki W, Yoshida T.
    • Journal Title

      J Cell Physiol.

      Volume: 28(Epub ahead of prints)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Dynamic expression of tenascin-C after myocardial ischemia and reperfusion : assessment by 125I-anti-tenascin-C antibody imaging.2010

    • Author(s)
      Taki J, Inaki A, Wakabayashi H, Imanaka-Yoshida K, Ogawa K, Hiroe M, Shiba K, Yoshida T, Kinuya S.
    • Journal Title

      J Nucl Med

      Volume: 51 Pages: 1116-1122

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] テネイシンCの役割2010

    • Author(s)
      今中恭子
    • Journal Title

      総合臨床

      Volume: 59 Pages: 1725-1728

    • Related Report
      2010 Annual Research Report
  • [Journal Article] Role of mesodermal FGF8 and FGF10 overlaps in the development of the arterial pole of the heart and pharyngeal arch arteries.2010

    • Author(s)
      Watanabe Y, Miyagawa-Tomita S, Vincent SD, Kelly RG, Moon AM, Buckingham ME
    • Journal Title

      Circulation Research 106

      Pages: 495-503

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Tenascin-C may aggravate left ventricular remodeling and function after myocardial infarction in mice.2010

    • Author(s)
      Nishioka T, Onishi K, Shimojo N, Nagano Y, Matsusaka H, Ikeuchi M, Ide T, Tsutsui H, Hiroe M, Yoshida T, Imanaka-Yoshida K.
    • Journal Title

      Am J Physiol Heart Circ Physiol 298

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 冠血管の発生2009

    • Author(s)
      宮川-富田幸子、今中恭子
    • Journal Title

      細胞 14

      Pages: 6-9

    • Related Report
      2010 Final Research Report
  • [Journal Article]2009

    • Author(s)
      Shirai M, Imanaka-Yoshida K, Schneider MD, Schwartz RJ, Morisaki T
    • Journal Title

      Proc Natl Acad Sci USA 106

      Pages: 18604-18609

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] 冠血管の発生2009

    • Author(s)
      宮川-富田幸子, ら
    • Journal Title

      細胞 14

      Pages: 6-9

    • Related Report
      2009 Annual Research Report
  • [Journal Article] T-box 2, a mediator of Bmp-Smad signaling, induced hyaluronan synthase 2 and Tgfbeta2 expression and endocardial cushion formation.2009

    • Author(s)
      Shirai M, Imanaka-Yoshida K, Schneider MD, Schwartz RJ, Morisaki T.
    • Journal Title

      Proc Natl Acad Sci U S A 106

      Pages: 18604-9

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] An FGF autocrine loop initiated in second heart field mesoderm regulates morphogenesis at the arterial pole of the heart2008

    • Author(s)
      Eon Joo Park, Watanabe Y, Smyth G, Miyagawa-Tomita S, Meyers E, Klingensmith J, Camenisch T, Buckingham M, Moon AM
    • Journal Title

      Development 135

      Pages: 3599-3610

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] 心外膜原基由来細胞を制御するテネイシンCの検討2008

    • Author(s)
      宮川-富田幸子、杉村洋子、中西敏雄、今中-吉田恭子
    • Journal Title

      日本小児循環器学会誌 24

      Pages: 20-28

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] An FGF autocrine loop initiated in second heart field mesoderm regulates morphogenesis at the arterial pole of the heart2008

    • Author(s)
      Eon Joo Park, et al.
    • Journal Title

      Development 135

      Pages: 3599-3610

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 心外膜原基由来細胞を制御するテネイシンCの検討2008

    • Author(s)
      宮川-富田 幸子ら.
    • Journal Title

      日本小児循環器学会雑誌 24

      Pages: 20-28

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Matricelular proteins-New molecular targets to prevent heart failure

    • Author(s)
      Okamoto H, Imanaka-Yoshida K
    • Journal Title

      Cardiovasc.Ther. (in press)

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Tenascin C may regulate the recruitment of smooth muscle cells during coronary artery development

    • Author(s)
      Ando K, Takahashi M, Yamagishi T, Miyagawa-Tomita S, Imanaka-Yoshida K, Yoshida T, Nakajima Y
    • Journal Title

      Differentiation (in press)

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Matricellular proteins-New molecular targets to prevent heart failure.

    • Author(s)
      Okamoto H, Imanaka-Yoshida K
    • Journal Title

      Cardiovasc.Ther

      Volume: (in press)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Tenascin C may regulate the recruitment of smooth muscle cells during coronary artery development

    • Author(s)
      Ando K, Takahashi M, Yamagishi T, Miyagawa-Tomita S, Imanaka-Yoshida K, Yoshida T, Nakajima Y.
    • Journal Title

      Differentiation

      Volume: (in press)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Presentation] 心臓形態形成・改変における細胞外マトリックスの役割-心臓を創り直す手がかり2010

    • Author(s)
      今中恭子
    • Organizer
      心臓血管発生研究会、特別シンポジウム
    • Place of Presentation
      千葉
    • Year and Date
      2010-07-10
    • Related Report
      2010 Final Research Report
  • [Presentation] 心臓形態形成・改変における細胞外マトリックスの役割-心臓を創り直す手がかり2010

    • Author(s)
      今中恭子
    • Organizer
      心臓血管発生研究会
    • Place of Presentation
      千葉
    • Year and Date
      2010-07-10
    • Related Report
      2010 Annual Research Report
  • [Presentation] Tenascin-C may regulate recruitment of mural cells during coronary arterial development2010

    • Author(s)
      Imanaka-Yoshida K, Ando K, Yamagishi T, Yoshida T, Nakajima Y, Miyagawa-Tomita S
    • Organizer
      Weinstein Cardiovascular Development Conference
    • Place of Presentation
      Amsterdam, The Netherlands
    • Related Report
      2010 Final Research Report
  • [Presentation] Tenascin C as a Target for Regulation of Cardiac Remodeling. Keystone Symposia2010

    • Author(s)
      今中-吉田恭子
    • Organizer
      Cardiovascular Development and Repair
    • Place of Presentation
      Keystone, Colorado, USA
    • Related Report
      2010 Final Research Report
  • [Presentation] Tenascin C may regulate recruitment of mural cells during coronary arterial development2010

    • Author(s)
      Imanaka-Yoshida K, Ando K, Yamagishi T, Yoshida T, Nakajima Y, Miyagawa-Tomita S.
    • Organizer
      Weinstein Cardiovascular Development Conference
    • Place of Presentation
      Amsterdam, Netherlands
    • Related Report
      2010 Annual Research Report
  • [Presentation] TGF-beta3 and MMP3 contribute to pathogenesis of myxomatous mitral valve in canine.2010

    • Author(s)
      Obayashi K, Miyagawa-Tomita S, Matsumoto H, Koyama H, Nakanishi T, Hirose H.
    • Organizer
      Weinstein Cardiovascular Development Conference
    • Place of Presentation
      Amsterdam, Netherlands
    • Related Report
      2010 Annual Research Report
  • [Presentation] Endothelin type-A receptor expression defines a distinct subdomain with in the crescent-forming heart field contributing to chamber myocardium.2010

    • Author(s)
      Asai R, Kurihara Y, Sato T, Kawamura Y, Kokubo H, Tonami K, Uchijima Y, Saga Y, Miyagawa-Tomita S, Kurihara H.
    • Organizer
      Weinstein Cardiovascular Development Conference
    • Place of Presentation
      Amsterdam, Netherlands
    • Related Report
      2010 Annual Research Report
  • [Presentation] The transcriptional repressor prdm1/blimp1 is required within the second heart field for the morphogenesis of the distal outflow tract.2010

    • Author(s)
      Vincent SD, Miyagawa-Tomita S, Buckingham M
    • Organizer
      Weinstein Cardiovascular Development Conference
    • Place of Presentation
      Amsterdam, Netherlands
    • Related Report
      2010 Annual Research Report
  • [Presentation] Hesr2 disrupted mice develop aortic valve disease with advancing age.2010

    • Author(s)
      Kokubo H, Miyagawa-Tomita S, Nakashima Y, Nakanishi T.
    • Organizer
      3^<rd> Congress of Asia-Pacific Cardiac Society
    • Place of Presentation
      Chiba
    • Related Report
      2010 Annual Research Report
  • [Presentation] 成獣Hesr2ノックアウトマウスの心機能解析2010

    • Author(s)
      中罵八隅、宮川-富田幸子、富松宏文、中西敏雄、小久保博樹
    • Organizer
      第46回日本小児循環器学会
    • Place of Presentation
      千葉
    • Related Report
      2010 Annual Research Report
  • [Presentation] Endothelin type-A receptor expression defines a distinct subpopulation within the first heart field contributing to chamber myocardium2010

    • Author(s)
      浅井理恵子、栗原由紀子、藤澤興、佐藤崇裕、河村悠美子、小久保博樹、磯波一夫、西山功一、内島泰信、宮川-富田幸子、栗原裕基
    • Organizer
      第33回日本分子生物学会
    • Place of Presentation
      神戸
    • Related Report
      2010 Annual Research Report
  • [Presentation] Tenascin C as a Target for Regulation of Cardiac Remodeling2010

    • Author(s)
      Imanaka-Yoshida, K.
    • Organizer
      Keystone Symposia : Cardiovascular Development and Repair
    • Place of Presentation
      Keystone, Colorado,アメリカ合衆国
    • Related Report
      2009 Annual Research Report
  • [Presentation] Endothelin type-A receptor expression defines a distinct subdomain within the first heart field contributing to chamber myocardium2009

    • Author(s)
      浅井理恵子, 栗原由起子,佐藤宗裕,河村美子,小久保博樹,相賀裕美子,宮川-富田幸子, 栗原裕基
    • Organizer
      第32回日本分子生物学会
    • Place of Presentation
      神奈川
    • Related Report
      2010 Final Research Report
  • [Presentation] Tenascin C regulates recruitment of smooth muscle cells during coronary arterial development2009

    • Author(s)
      Ando K, Yamagishi T, Miyagawa-Tomita S, Imanaka-Yoshida K, Yoshida T, Nakajima Y
    • Organizer
      49^<th> Ann Meeting of the American Society for Cell Biology(2012)(B391)
    • Place of Presentation
      カリフォルニア、米国
    • Related Report
      2010 Final Research Report
  • [Presentation] テネイシンCによる心臓血管新生の制御2009

    • Author(s)
      今中-吉田恭子,原万里,浪方美幸,レオンバルディビィアサライサベル,堰本晃代,吉田利通,宮川-富田幸子
    • Organizer
      第13回Molecular Cardiovascular Conference
    • Place of Presentation
      小樽
    • Related Report
      2010 Final Research Report 2009 Annual Research Report
  • [Presentation] Margaret Buckingham心臓円錐動脈幹と鰓弓動脈の発生における中胚葉性fgf8とfgf10の機能解析2009

    • Author(s)
      渡辺祐介, 宮川-富田幸子, Robert Kelly, Anne Moon
    • Organizer
      第8回心臓血管発生研究会
    • Place of Presentation
      福島
    • Related Report
      2010 Final Research Report
  • [Presentation] 僧帽弁閉鎖不全症発症におけるTGFβ3およびMMP3の役割2009

    • Author(s)
      大林浩二,宮川-富田幸子,松本浩毅、小山秀一、廣瀬昶
    • Organizer
      日本臨床獣医学会(22)
    • Place of Presentation
      埼玉
    • Related Report
      2010 Final Research Report
  • [Presentation] Endothelin typeA-receptor expression defines a distinct subpopulation within the first heart field contributing to chamber myocardium2009

    • Author(s)
      Asai R, Kurihara Y, Sato T,Kawamura Y,Kokubo H, Miyagawa-Tomita S
    • Organizer
      42^<nd> Ann Meet Jpn Soc Dev Biol
    • Place of Presentation
      Nigata
    • Related Report
      2010 Final Research Report
  • [Presentation] The transcriptional repressor prdm1/blimp1 is required within the second heart field for the morphogenesis of the distal outflow tract2009

    • Author(s)
      Vincent SD, Miyagawa-Tomita S, Buckingham M
    • Organizer
      Weinstein Cardiovascular Developmental Conference
    • Place of Presentation
      California, USA
    • Related Report
      2010 Final Research Report
  • [Presentation] TGF-β3 and MMP3 contribute to pathogenesis of myxomatous mitral valve in canine2009

    • Author(s)
      Obayashi K, Miyagawa-Tomita S, Matsumoto H, Koyama H, Nakanishi T, Hirose H
    • Organizer
      Weinstein Cardiovascular Developmental Conference, 148
    • Place of Presentation
      California, USA
    • Related Report
      2010 Final Research Report
  • [Presentation] Endothelin type-A receptor expression defines a distinct subdomain within the crescent-forming heart field contributing to chamber myocardium2009

    • Author(s)
      Asai R, Kurihara Y, Sato T, Kawamura Y, Kokubo H, Tonami K, Uchijima Y, Saga Y, Miyagawa-Tomita S, Kurihara H
    • Organizer
      Weinstein Cardiovascular Developmental Conference
    • Place of Presentation
      California, USA
    • Related Report
      2010 Final Research Report
  • [Presentation] Tenascin-C expression and neural crest are associated with formation of the coronary orifice2009

    • Author(s)
      Miyagawa-Tomita S, Sugimura H, Tomimatsu H, Yoshida T, Nakanishi T, Imanaka-Yoshida K
    • Organizer
      Weinstein Cardiovascular Developmental Conference
    • Place of Presentation
      California, USA
    • Related Report
      2010 Final Research Report
  • [Presentation] 僧帽弁閉鎖不全症発症におけるTGFbetaの役割2009

    • Author(s)
      大林浩二、宮川-富田幸子、松本浩毅、小山秀一、廣瀬昶
    • Organizer
      第147回日本獣医学会
    • Place of Presentation
      栃木
    • Related Report
      2010 Final Research Report
  • [Presentation] 僧帽弁閉鎖不全症発症におけるTGFβの役割2009

    • Author(s)
      大林浩二、宮川-富田幸子, ら
    • Organizer
      第147回日本獣医学会
    • Place of Presentation
      栃木
    • Related Report
      2009 Annual Research Report
  • [Presentation] Tenascin-C expression and neural crest are associated with formation of the coronary orifice.2009

    • Author(s)
      Miyagawa-Tomita S, et al.
    • Organizer
      Weinstein Cardiovascular Developmental Conference
    • Place of Presentation
      カリフォルニア、米国
    • Related Report
      2009 Annual Research Report
  • [Presentation] Endothelin type-A receptor expression defines a distinct subdomain within the crescent-forming heart field contributing to chamber myocardium2009

    • Author(s)
      Asai R, et al.
    • Organizer
      Weinstein Cardiovascular Developmental Conference
    • Place of Presentation
      カリフォルニア、米国
    • Related Report
      2009 Annual Research Report
  • [Presentation] The transcriptional repressor prdml/blimpl is required within the second heart field for the morphogenesis of the dlstal outflow tract2009

    • Author(s)
      Vincent SD, Miyagawa-Tomita S, et al.
    • Organizer
      Weinstein Cardiovascular Developmental Conference
    • Place of Presentation
      カリフォルニア、米国
    • Related Report
      2009 Annual Research Report
  • [Presentation] Endothelin typeA-receptor expression defines a distinct subpopulation within the first heart field contributing to chamber myocardium.2009

    • Author(s)
      Asai R, et al.
    • Organizer
      42^<nd> Ann Meet Jpn Soc Dev Biol
    • Place of Presentation
      新潟
    • Related Report
      2009 Annual Research Report
  • [Presentation] 僧帽弁閉鎖不全症発症におけるTGFβ3およびMMP3の役割2009

    • Author(s)
      大林浩二、宮川-富田幸子, ら
    • Organizer
      日本臨床獣医学会
    • Place of Presentation
      埼玉
    • Related Report
      2009 Annual Research Report
  • [Presentation] 僧帽弁粘液腫様変性におけるTGFβの役割2009

    • Author(s)
      大林浩二、宮川-富田幸子, ら
    • Organizer
      第45回日本小児循環器学会
    • Place of Presentation
      神戸
    • Related Report
      2009 Annual Research Report
  • [Presentation] 心臓円錐動脈幹と鰓弓動脈の発生における中胚葉性fgf8とfgf10の機能解析2009

    • Author(s)
      渡辺祐介、宮川-富田幸子, ら
    • Organizer
      第8回心臓血管発生研究会
    • Place of Presentation
      福島
    • Related Report
      2009 Annual Research Report
  • [Presentation] Tenascin C regulates recruitment of smooth muscle cells during coronary arterial development.2009

    • Author(s)
      Ando K, et al.
    • Organizer
      49^<th> Ann Meeting of the American Society for Cell Biology
    • Place of Presentation
      カリフォルニア、米国
    • Related Report
      2009 Annual Research Report
  • [Presentation] Endothelin type-A receptor expression defines a distinct subdomain within the first heart field contributing to chamber myocardium.2009

    • Author(s)
      浅井理恵子, ら
    • Organizer
      第32回日本分子生物学会
    • Place of Presentation
      神奈川
    • Related Report
      2009 Annual Research Report
  • [Presentation] 鶏胚の心臓流出路におけるアポトーシスの検討2008

    • Author(s)
      吉岡朋子、宮川-富田幸子
    • Organizer
      第1回Tokyo Heart Development Club
    • Place of Presentation
      東京女子医科大学、東京
    • Year and Date
      2008-04-18
    • Related Report
      2010 Final Research Report
  • [Presentation] Hesr2 knockout mice show calcification in the aortic valve2008

    • Author(s)
      Kokubo H, Miyagawa-Tomita S, Nakashima Y, Nakanishi T, Saga Y
    • Organizer
      31^<st> Mol Biol Soc Japan and 81^<st> Jpn Biochem Soc Meeting(2T22-1)(2P-1160)
    • Place of Presentation
      Kobe, Japan
    • Related Report
      2010 Final Research Report
  • [Presentation] Relationship the cardiac conduction system and endthelinA receptor-LacZ/EGFP expression cells in early cardiac development2008

    • Author(s)
      Asai R, Sato M, Kawamura Y, Miyagawa-Tomita S, Kurihara Y, Kurihara H
    • Organizer
      31^<st> Mol Biol Soc Japan and 81^<st> Jpn Biochem Soc Meeting(2P-0992)
    • Place of Presentation
      Kobe, Japan
    • Related Report
      2010 Final Research Report
  • [Presentation] Function of Histon H3-K9 methylase, G9 and GLP in cardiac development2008

    • Author(s)
      Inagawa K, Kojima M, Nakajima K, Miyagawa-Tomita S, Tachibana M, Managai Y, Takeuchi T
    • Organizer
      31^<st> Mol Biol Soc Japan and 81^<st> Jpn Biochem Soc Meeting(4P-0841)
    • Place of Presentation
      Kobe, Japan
    • Related Report
      2010 Final Research Report
  • [Presentation] 心臓形態形成におけるテネイシンCの役割2008

    • Author(s)
      原万里、浪方美幸、ポンセデレオンバルディビアサライサベル、堰本晃代、吉田利通、宮川-富田幸子、今中-吉田恭子
    • Organizer
      第30回心筋生検研究会(p-30)
    • Place of Presentation
      三重
    • Related Report
      2010 Final Research Report
  • [Presentation] Hesr2欠損マウスは石灰化大動脈弁を示す2008

    • Author(s)
      小久保博樹、宮川-富田幸子、中嶌八隅、中西敏雄、相賀裕美子
    • Organizer
      第30回心筋生検研究会(p-11)
    • Place of Presentation
      三重
    • Related Report
      2010 Final Research Report
  • [Presentation] 鳥類モデルを用いた冠動脈血管新生の解析2008

    • Author(s)
      宮川-富田幸子、杉村洋子、富松宏文、中西敏雄
    • Organizer
      第30回心筋生検研究会(シンポジウム5)
    • Place of Presentation
      三重
    • Related Report
      2010 Final Research Report
  • [Presentation] Role of Fgf8 and Fgf10 during second heart field and pharyngeal arch artery development2008

    • Author(s)
      Watanabe Y, Miyagawa-Tomita S, Park EJ, Kelly R, Moon A, Buckingham M
    • Organizer
      Frontiers in Developmental Biology
    • Place of Presentation
      Giens, France
    • Related Report
      2010 Final Research Report
  • [Presentation] Relationship the cardiac conduction sytem and endthelin A receptor-LacZ/EGFP expression cells in early cardiac development2008

    • Author(s)
      Asai R, Sato M, Kawamura Y, Miyagawa-Tomita S, Kurihara Y, Kurihara H
    • Organizer
      Frontiers in Developmental Biology
    • Place of Presentation
      Giens, France
    • Related Report
      2010 Final Research Report
  • [Presentation] hesr2ノックアウトマウスに認められる大動脈弁石灰化2008

    • Author(s)
      小久保博樹、宮川-富田幸子、中嶌八隅、中西敏雄、相賀裕美子
    • Organizer
      第7回心臓血管発生研究会、12
    • Place of Presentation
      福島
    • Related Report
      2010 Final Research Report
  • [Presentation] TGF-betaの僧帽弁編成における役割2008

    • Author(s)
      大林浩二、宮川-富田幸子
    • Organizer
      第7回心臓血管発生研究会、11
    • Place of Presentation
      福島
    • Related Report
      2010 Final Research Report
  • [Presentation] 心臓形態形成におけるテネイシンCの役割2008

    • Author(s)
      原万里、波方美幸、Ponse de Leon BSI, 堰本晃代、吉田利通、宮川-富田幸子、今中-吉田恭子
    • Organizer
      第7回心臓血管発生研究会、10
    • Place of Presentation
      福島
    • Related Report
      2010 Final Research Report
  • [Presentation] 心臓発生初期におけるendthelinA受容体-LacZ/EGFP発現細胞と刺激伝導系の関連2008

    • Author(s)
      浅井理恵子、佐藤崇裕、河村悠美子、宮川-富田幸子、栗原由紀子、栗原裕基
    • Organizer
      第7回心臓血管発生研究会、5
    • Place of Presentation
      福島
    • Related Report
      2010 Final Research Report
  • [Presentation] ワークショップ、心臓刺激伝導系の発生-最近のトピックス-2008

    • Author(s)
      宮川-富田幸子
    • Organizer
      第7回心臓血管発生研究会
    • Place of Presentation
      福島
    • Related Report
      2010 Final Research Report
  • [Presentation] Hesr2 disrupted mice develop dysfunction of the semilunar valve with age2008

    • Author(s)
      Kokubo H, Miyagawa-Tomita S, Saga Y
    • Organizer
      44^<th> Ann Meeting Jpn Soc Ped, I-D-19
    • Place of Presentation
      Fukushima, Japan
    • Related Report
      2010 Final Research Report
  • [Presentation] 冠動脈開口部形成には心臓神経堤細胞が関与する2008

    • Author(s)
      宮川-富田幸子
    • Organizer
      シンポジウム"心臓血管発生:先天性心疾患予防へ向けて"第44回日本小児循環器学会
    • Place of Presentation
      福島
    • Related Report
      2010 Final Research Report
  • [Presentation] Fgf autocrine loop initiated in second heart field mesoderm regulates morphogenesis at the arterial pole of the heart2008

    • Author(s)
      Park EJ, Watanabe Y, Smyth G, Miyagawa-Tomita S, Meyers EN, Klingensmith J, Camenisch T, Buckingham M, Moon AM
    • Organizer
      Weinstein Cardiovascular Development Conference, 9
    • Place of Presentation
      Houston, Texas, USA
    • Related Report
      2010 Final Research Report
  • [Presentation] Role of Fgf8 and Fgf10 during second heart field and pharyngeal arch artery development2008

    • Author(s)
      Watanabe Y, Miyagawa-Tomita S, Park EJ, Kelly R, Moon A, Buckingham M
    • Organizer
      Weinstein Cardiovascular Development Conference, 180
    • Place of Presentation
      Houston, Texas, USA
    • Related Report
      2010 Final Research Report
  • [Presentation] Tenascin-C may play a significant role in maturation of coronary arteries in mouse2008

    • Author(s)
      Imanaka-Yoshida K, Hara M, Namikata M, Yoshida T, Schwartz RJ, Miyagawa-Tomita S
    • Organizer
      Weinstein Cardiovascular Development Conference,97
    • Place of Presentation
      Houston, Texas, USA
    • Related Report
      2010 Final Research Report
  • [Presentation] Neural crest and proepicardial cells contribute to formation of the coronary orifice with Tenascin-C2008

    • Author(s)
      Miyagawa-Tomita S, Sugimura H, Nakanishi Toshio, Imanaka-Yoshida K
    • Organizer
      Weinstein Cardiovascular Development Conference,148
    • Place of Presentation
      Houston, Texas, USA
    • Related Report
      2010 Final Research Report
  • [Presentation] Role of Fgf signaling during anterior heart field and pharyngeal arch artery development2008

    • Author(s)
      Watanabe Y, Miyagawa-Tomita S, Robert GK, Moon A, Buckingham M
    • Organizer
      HeartRepair 2^<nd> Annual Meeting
    • Place of Presentation
      Madrid, Spain
    • Related Report
      2010 Final Research Report
  • [Presentation] 冠動脈開口部形成には心臓神経堤細胞が関与する2008

    • Author(s)
      宮川-富田 幸子ら
    • Organizer
      日本小児循環器学会
    • Place of Presentation
      福島
    • Related Report
      2008 Annual Research Report
  • [Presentation] 鳥類モデルを用いた冠動脈血管新生の解析2008

    • Author(s)
      宮川-富田 幸子ら
    • Organizer
      第30回心筋生検研究会
    • Place of Presentation
      三重
    • Related Report
      2008 Annual Research Report
  • [Book] Annual Review循環器(山口徹他編集)(心臓発生と心筋分化誘導のマスター因子)2011

    • Author(s)
      竹内純、宮川-富田幸子、笹岡陽介、小柴和子
    • Total Pages
      365
    • Publisher
      中外医学社
    • Related Report
      2010 Final Research Report
  • [Book] Annual Review循環器(山口徹他編集)(細胞外マトリックス調節因子)2011

    • Author(s)
      今中恭子
    • Total Pages
      365
    • Publisher
      中外医学社
    • Related Report
      2010 Final Research Report
  • [Book] Annual Review循環器(山口徹、高本真一、小室一成、佐地勉編)2011

    • Author(s)
      竹内純、宮川-富田幸子、笹岡陽介、小柴和子
    • Publisher
      中外医学社(心臓発生と心筋分化誘導のマスター因子(分担))
    • Related Report
      2010 Annual Research Report
  • [Book] Annual Review循環器(山口徹、高本真一、小室一成、佐地勉編)2011

    • Author(s)
      今中恭子
    • Publisher
      中外医学社(細胞外マトリックス調節因子(分担))
    • Related Report
      2010 Annual Research Report
  • [Book] Dogs and Cats 犬と猫の診療指針(Clinical Veterinary Advisor クリニカルベテリナリーアドバイザー)2010

    • Author(s)
      Etienne Cote監修、長谷川篤彦監訳
    • Total Pages
      1851
    • Publisher
      Mosby (Elsevier) interzoo発行 Mosby Elsevier Inc.
    • Related Report
      2010 Final Research Report

URL: 

Published: 2008-04-01   Modified: 2016-04-21  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi