| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2009: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2008: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Research Abstract |
This study aimed to clarify the stimulus responses which carry out selection of centromere autoantigens from maculomolecular complexes including more than forty proteins. We examined immunoreactivities of nine different kinds of centromere proteins, which are different from three major centromere autoantigens, against sera from many patients and confirmed that a few of them reacted with a few patients'sera. At present, we have not identified any factors which might differentiate major centromere autoantigens from minor autoantigens that rarely react to autoantibodies.
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