Regulation of Langerhans cell function by fibroblasts
| Project/Area Number |
20591336
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|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
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| Research Field |
Dermatology
|
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| Research Institution | The University of Tokyo |
|---|
Principal Investigator |
TADA Yayoi The University of Tokyo, 医学部附属病院, 講師 (00334409)
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|---|
| Project Period (FY) |
2008 – 2010
|
| Project Status |
Completed (Fiscal Year 2010)
|
| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2009: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2008: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
|
|---|
| Keywords | 樹状細胞 / 線維芽細胞 |
|---|
| Research Abstract |
Molecules which are released from dead cells and activate immune systems are called danger signals. We found that one of such danger signals, monosodium urate crystal, induces Langerhans cell migration to the lymph node and augment contact hypersensitivity.
|
Report
(4 results)
Research Products
(16 results)
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[Journal Article] Identification of a novel marker for dendritic cell maturation, mouse transmembrane protein 123.2010
Author(s)
Takekoshi T, Tada Y, Watanabe T, Sugaya M, Hoashi T, Komine M, Kawashima T, Shimizu T, Hau CS, Asahina A, Yokomizo T, Sato S, Tamaki K
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Journal Title
J Biol Chem. 285
Pages: 31876-84
Related Report
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[Journal Article] Possible roles of IL-27 in the pathogenesis of psoriasis.2010
Author(s)
Shibata S, Tada Y, Kanda N, Nashiro K, Kamata M, Karakawa M, Miyagaki T, Kai H, Saeki H, Shirakata Y, Watanabe S, Tamaki K, Sato S
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Journal Title
J Invest Dermatol. 130
Pages: 1034-9
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