Developmental change of prefrontal function in children with Autism spectrum disorders
Project/Area Number |
20591391
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Psychiatric science
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Research Institution | The University of Tokyo |
Principal Investigator |
WATANABE Keiichiro (2009-2010) The University of Tokyo, 学生相談ネットワーク本部, 講師 (10323586)
川久保 友紀 (2008) The University of Tokyo, 医学部附属病院, 特任助教 (40396718)
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Co-Investigator(Kenkyū-buntansha) |
KAWAKUBO Yuki 東京大学, 医学部付属病院, 特任助教 (40396718)
KIM Sooyung 東京大学, 医学部附属病院, 特任助教 (90401108)
渡辺 慶一郎 東京大学, 医学部・附属病院, 特任講師 (10323586)
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Co-Investigator(Renkei-kenkyūsha) |
ISHII Ayaka 東京大学, 医学部付属病院, 助教 (40609020)
KASAI Kiyoto 東京大学, 医学部附属病院, 教授 (80322056)
|
Project Period (FY) |
2008 – 2010
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Project Status |
Completed (Fiscal Year 2010)
|
Budget Amount *help |
¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Fiscal Year 2010: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2009: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2008: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
|
Keywords | 発達障害 / 神経心理 / 脳・神経 / 自閉症 / 認知科学 |
Research Abstract |
The aim of this study was exploring the developmental change of prefrontal function in children with autism spectrum disorders (ASD) using the near-infrared spectroscopy. In the typically developing children, the relative change of oxy-hemoglobin was correlated with their age. On the other hand, children with ASD presented the smaller change than age- and IQ-matched typically developing children. Furthermore, there were no correlations between the oxy-hemoglobin and their age.
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Report
(4 results)
Research Products
(31 results)
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[Journal Article] Task dependent prefrontal dysfunction in persons with Asperger's disorder investigated with multi-channel near-infrared spectroscopy.2011
Author(s)
Iwanami A., Okajima Y, Ota H, Tani M, Yamada T, Hashimoto R, Kanai C, Watanabe H, Yamasue H, Kawakubo Y, Kato N
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Journal Title
Research in Autism Spectrum Disorders 5(3)
Pages: 1187-1193
Related Report
Peer Reviewed
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[Journal Article] Task dependent prefrontal dysfunction in persons with Asperger's disorder investigated with multi-channel near-infrared spectroscopy.2011
Author(s)
Iwanami A, Okajima Y, Ota H, Tani M, Yamada T, Hashimoto R, Kanai C, Watanabe H, Yamasue H, Kawakubo Y, Kato N
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Journal Title
Research in Autism Spectrum Disorders
Volume: 5
Pages: 1187-1193
Related Report
Peer Reviewed
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[Journal Article] Association study of the commonly recognized breakpoints in chromosome 15q11-q13 in Japanese autistic patients2008
Author(s)
C.Kato, M.Tochigi, S.Koishi, Y.Kawakubo, K.Yamamoto, H.Matsumoto, O.Hashimoto, S.Y.Kim, K.Watanabe, Y., 他
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Journal Title
Pgychiatr Genet 18
Pages: 133-136
Related Report
Peer Reviewed
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[Journal Article] Associations study of the 15q11-q13 maternal expression domain in Japanese autistic patients2008
Author(s)
C.Kato, M.Tochigi, J.Ohashi, S.Koishi, Y.Kawakubo, K.Yamamoto, H.Matsumoto, O.Hashimoto, S.Y.Kim, K.Watanabe, 他
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Journal Title
Am J Med Genet B Neuropsychiatr Genet 147
Pages: 1008-1012
Related Report
Peer Reviewed
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[Journal Article] No association between the ryanodine receptor 3 gene and autism in a Japanese population2008
Author(s)
M.Tochigi, C.Kato, J.Ohashi, S.Koishi, Y.Kawakubo,, K.Yamamoto, H.Matsumoto, O.Hashimoto, S.Y.Kim, K.Watanabe, Y.Kmmo, E.
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Journal Title
Psychiatry Clin Neurosci 62
Pages: 341-344
Related Report
Peer Reviewed
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[Journal Article] No association between the ryanodine receptor 3 gene and autism in a Japanese population2008
Author(s)
M. Tochigi, C. Kato, J. Ohashi, S. Koishi, Y. Kawakubo, K. Yamamoto, H. Matsumoto, O. Hashimoto, S. Y. Kim, K. Watanabe, Y. Kmmo, E.
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Journal Title
Psychiatry Clin Neurosci 62
Pages: 341-344
Related Report
Peer Reviewed
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[Journal Article] Associations study of the 15q11-q13 maternal expression domain in Japanese autistic patients2008
Author(s)
C. Kato, M. Tochigi, J. Ohashi, S. Koishi, Y. Kawakubo, K. Yamamoto, H. Matsumoto, O. Hashimoto, S. Y. Kim, K. Watanabe, Y. Kano, E. Nanba, N. Kato and T.Sasaki
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Journal Title
Am J Med Genet B Neuropsychiatr Genet 147
Pages: 1008-1012
Related Report
Peer Reviewed
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[Journal Article] Association study of the commonly recognized breakpoints in chromosome 15q11-q13 in Japanese autistic patients2008
Author(s)
C. Kato, M. Tochigi, S. Koishi, Y. Kawakubo, K. Yamamoto, H. Matsumoto, 0. Hashimoto, S. Y. Kim, K. Watanabe, Y. Kano, E. Nanba, N. Kato and T. Sasaki
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Journal Title
Pgychiatr Genet 18
Pages: 133-136
Related Report
Peer Reviewed
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