| Project/Area Number |
20591420
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Psychiatric science
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| Research Institution | Teikyo University |
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Principal Investigator |
IKEBUCHI Emi Teikyo University, 医学部, 教授 (20246044)
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| Project Period (FY) |
2008 – 2010
|
| Project Status |
Completed (Fiscal Year 2010)
|
| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2010: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2009: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2008: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Keywords | 精神科リハビリテーション医学 / 統合失調症 / 初発エピソード / 認知機能障害 / 追跡研究 / 社会機能 / 精神症状 / 社会的機能 / 認知機能リハビリテーション |
|---|
| Research Abstract |
Cognitive impairment of first episode schizophrenia was followed prospectively and cross-sectional to clarify time course and influence of cognitive functioning on psychiatric symptoms and social functioning. Twelve schizophrenia diagnosed with DSM IV were evaluated at baseline, after 6 months, and after 1 year using with BACS-J, PANSS, LSP, and GAF. Verbal memory, motor speed, and executive functioning were significantly improved after 1 year. Social relationship, communication skills, and GAF also significantly improved after 1 year. Nineteen first episode schizophrenia (after 6 month follow up point) were compared with 18 schizophrenia (DSM-IV) who were speculated that onset was 5 years ago. Five years group were significantly better in verbal fluency, social relationship, and general pathology than first episode group. Five years group were significantly worse in verbal memory and executive functioning.
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