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Diffusion tensor imaging in patients with major depression

Research Project

Project/Area Number 20591430
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Radiation science
Research InstitutionHokkaido University

Principal Investigator

TERAE Satoshi  Hokkaido University, 病院, 准教授 (40240634)

Co-Investigator(Kenkyū-buntansha) INOUE Takeshi  北海道大学, 病院, 講師 (70250438)
NAKAGAWA Shin  北海道大学, 病院, 講師 (60360905)
KUDO Kohsuke  岩手医科大学, 先端科学技術研究センター, 講師 (10374232)
Project Period (FY) 2008 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2008: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
KeywordsMRI / うつ病 / 拡散テンソル
Research Abstract

Diffusion tensor imaging (DTI) was conducted in 13 treatment-resistant, 12 nontreatment-resistant, and 19 drug-naive patients with major depression. As compared with normal control subjects, a voxel-based analysis revealed significant decrease in fractional anisotropy (FA) in the right frontal white matter in the treatment-resistant patients. Histogram analysis demonstrated significant decrease in peak position of FA histogram of the drug-naive patients. No significant correlation was observed between the FA abnormality and clinical severity as assessed by HDRS, GAF, and MADRS.

Report

(4 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (79 results)

All 2011 2010 2009 2008

All Journal Article (40 results) (of which Peer Reviewed: 40 results) Presentation (35 results) Book (4 results)

  • [Journal Article] Susceptibility of Tmax to Tracer Delay on Perfusion Analysis: Quantitative Evaluation of Various Deconvolution Algorithms Using Digital Phantoms.2011

    • Author(s)
      Kudo K, Sasaki M, Ostergaard L, Christensen S, Uwano I, Suzuki M, Ogasawara K, Shirato H, Ogawa A.
    • Journal Title

      J Cereb Blood Flow Metab 31

      Pages: 908-912

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Prediction of infarct volume and neurologic outcome by using automated multiparametric perfusion-weighted magnetic resonance imaging in a primate model of permanent middle cerebral artery occlusion.2011

    • Author(s)
      Sasaki M, Kudo K, Honjo K, Hu JQ, Wang HB, Shintaku K.
    • Journal Title

      J Cereb Blood Flow Metab 31

      Pages: 448-456

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Non-Invasive Measurement of Oxygen Saturation in the Spinal vein using SWI: Quantitative Evaluation under Conditions of Physiological and Caffeine Load.2011

    • Author(s)
      Fujima N, Kudo K, Terae S, Ishizaka K, Yazu R, Zaitsu Y, Tha KK, Yoshida K, Tsukahara A, Haacke EM, Sasaki M, Shirato H.
    • Journal Title

      Neuroimage 54

      Pages: 344-349

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] High-resolution diffusion tensor imaging for the detection of diffusion abnormalities in the trigeminal nerves of patients with trigeminal neuralgia caused by neurovascular compression.2011

    • Author(s)
      Fujiwara S, Sasaki M, Wada T, Kudo K, Hirooka R, Ishigaki D, Nishikawa Y, Ono A, Yamaguchi M, Ogasawara K.
    • Journal Title

      J Neuroimaging 21

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Susceptibility-Weighted Imaging and Magnetic Resonance Angiography during Migraine Attack : A Case Report.2011

    • Author(s)
      Shimoda Y, Kudo K, Kuroda S, Zaitsu Y, Fujima N, Terae S, Sasaki M, Houkin K.
    • Journal Title

      Magn Reson Med Sci 10

      Pages: 49-52

    • NAID

      10029698098

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Long-term naturalistic follow-up of lithium augmentation : relevance to bipolarity.2011

    • Author(s)
      Inoue T, Abekawa T, Nakagawa S, Suzuki K, Tanaka T, Kitaichi Y, Boku S, Toda H, Koyama T
    • Journal Title

      J Affect Disord 129

      Pages: 64-67

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Long-term naturalistic follow-up of lithium augmentation : relevance to bipolarity2011

    • Author(s)
      Inoue T, Abekawa T, Nakagawa S, Suzuki K, Tanaka T, Kitaichi Y, Boku S, Toda H, Koyama T
    • Journal Title

      J Affect Disord

      Volume: 129 Pages: 64-67

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Susceptibility of Tmax to Tracer Delay on Perfusion Analysis : Quantitative Evaluation of Various Deconvolution Algorithms Using Digital Phantoms2011

    • Author(s)
      Kudo K, Sasaki M, Ostergaard L, Christensen S, Uwano I, Suzuki M, Ogasawara K, Shirato H, Ogawa A
    • Journal Title

      JCBFM

      Volume: (In press)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] High-resolution diffusion tensor imaging for the detection of diffusion a bnormalities in the trigeminal nerves of patients with trigeminal neuralgia caused by neurovascular compression.2011

    • Author(s)
      Fujiwara S, Sasaki M, Wada T, Kudo K, Hirooka R, Ishigaki D, Nishikawa Y, Ono A, Yamaguchi M, Ogasawara K
    • Journal Title

      J Neuroimaging

      Volume: (In press)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Susceptibility-Weighted Imaging and Magnetic Resonance Angiography during Migraine Attack : A Case Report2011

    • Author(s)
      Shimoda Y, Kudo K, Kuroda S, Zaitsu Y, Fujima N, Terae S, Sasaki M, Houkin K
    • Journal Title

      Magnetic Resonance in Medical Science

      Volume: (In press)

    • NAID

      10029698098

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Non-Invasive Measurement of Oxygen Saturation in the Spinal vein using SWI : Quantitative Evaluation under Conditions of Physiological and Caffeine Load2011

    • Author(s)
      Fujima N, Kudo K, Terae S, Ishizaka K, Yazu R, Zaitsu Y, Tha KK, Yoshida K, Tsukahara A, Haacke EM, Sasaki M, Shirato H
    • Journal Title

      Neuroimage

      Volume: 54 Pages: 344-349

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Pramipexole for stage 2 treatment-resistant major depression : an open study.2010

    • Author(s)
      Inoue T, Kitaichi Y, Masui T, Nakagawa S, Boku S, Tanaka T, Suzuki K, Nakato Y, Usui R, Koyama T
    • Journal Title

      Prog Neuropsychopharmacol Biol Psychiatry 34

      Pages: 1446-1449

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] In vivo topographic illustration of microstructural white matter abnormalities of multiple system atrophy by diffusion tensor imaging.2010

    • Author(s)
      Tha KK, Terae S, Yabe I, Miyamoto T, Soma H, Zaitsu Y, Fujima N, Kudo K, Sasaki H, Shirato H.
    • Journal Title

      Radiology 255

      Pages: 563-569

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Differences in CT Perfusion Maps Generated by Different Commercially Available Software : Analysis Using Identical Source Data of Acute Stroke Patients.2010

    • Author(s)
      Kudo K, Sasaki M, Yamada K, Momoshima S, Utsunomiya H, Shirato H, Ogasawara K.
    • Journal Title

      Radiology 254

      Pages: 200-209

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Visual discrimination among patients with depression and schizophrenia and healthy individuals using semiquantitative color-coded fast spin-echo T1-weighted magnetic resonance imaging.2010

    • Author(s)
      Sasaki M, Shibata E, Ohtsuka K, Endoh J, Kudo K, Narumi S, Sakai A.
    • Journal Title

      Neuroradiology 52

      Pages: 83-89

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Depression and major depressive disorder in patients with Parkinson's disease.2010

    • Author(s)
      井上猛
    • Journal Title

      Movement Disorders 25

      Pages: 44-49

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Pramipexole for stage 2 treatment-resistant major depression : an open study2010

    • Author(s)
      Inoue T, Kitaichi Y, Masui T, Nakagawa S, Boku S, Tanaka T, Suzuki K, Nakato Y, Usui R, Koyama T
    • Journal Title

      Prog Neuropsychopharmacol Biol Psychiatry

      Volume: 34 Pages: 1446-1449

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Microstructural white matter abnormalities of multiple system atrophy : in vivo topographic illustration by using diffusion-tensor MR imaging2010

    • Author(s)
      Tha KK, Terae S, Yabe I, Miyamoto T, Soma H, Zaitsu Y, Fujima N, Kudo K, Sasaki H, Shirato H
    • Journal Title

      Radiology

      Volume: 255 Pages: 563-569

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Susceptibility-Weighted Imaging of Cerebral Fat Embolism2010

    • Author(s)
      Zaitsu Y, Terae S, Kudo K, Tha KK, Hayakawa M, Fujima N, Yoshida D, Tsukahara A, Shirato H
    • Journal Title

      J Comput Assist Tomogr

      Volume: 34 Pages: 107-112

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Brain Temperature Measured by Proton Magnetic Resonance Spectroscopy Predicts Cerebral Hyperperfusion after Carotid Endarterectomy2010

    • Author(s)
      Murakamki T, Ogasawara K, Yoshioka Y, Ishigaki D, Sasaki M, Kudo K, Aso K, Nishimoto H, Kobayashi M, Yoshida K, Ogawa A
    • Journal Title

      Radiology

      Volume: 256 Pages: 924-931

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Prediction of infarct volume and neurologic outcome by using automated multiparametric perfusion-weighted magnetic resonance imaging in a primate model of permanent middle cerebral artery occlusion2010

    • Author(s)
      Sasaki M, Kudo K, Honjo K, Hu JQ, Wang HB, Shintaku K
    • Journal Title

      JCBFM

      Volume: (In press)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Depression and major depressive disorder in patients with Parkinson's disease.2010

    • Author(s)
      Inoue T
    • Journal Title

      Movement Disorders 25

      Pages: 44-49

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Differences in CT Perfusion Maps Generated by Different Commercially Available Software : Analysis Using Identical Source Data of Acute Stroke Patients2010

    • Author(s)
      Kudo K, Sasaki M, Yamada K, Momoshima S, Utsunomiya H, Shirato H, Ogasawara K
    • Journal Title

      Radiology 254

      Pages: 200-209

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Evaluation of Change in Venous Oxygenation by Susceptibility-Weighted Imaging in Patients with Spinal Arterio-Venous Malformations after Treatment2010

    • Author(s)
      Fujima N, Kudo K, Terae S, Hida K, Ishizaka K, Zaitsu Y, Asano T, Yoshida D, Tha KK, Sasaki M, Shirato H
    • Journal Title

      Radiology (In press)

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Visual discrimination among patients with depression and schizophrenia and healthy individuals using semiquantitative color-coded fast spin-echo T1-weighted magnetic resonance imaging2010

    • Author(s)
      Sasaki M, Shibata E, Ohtsuka K, Endoh J, Kudo K, Narumi S, Sakai A
    • Journal Title

      Neuroradiology 52

      Pages: 83-89

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] In vivo topographic illustration of microstructural white matter abnormalities of multiple system atrophy by diffusion tensor imaging2010

    • Author(s)
      Tha KK, Terae S, Yabe I, Miyamoto T, Soma H, Zaitsu Y, Fujima N, Kudo K, Sasaki H, Shirato H
    • Journal Title

      Radiology (In press)

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Differential diagnosis of hyperintense cerebrospinal fluid on fluid-attenuated inversion recovery images of the brain. Part II : non-pathological conditions.2009

    • Author(s)
      Tha KK, Terae S, Kudo K, Miyasaka K.
    • Journal Title

      Br J Radiol 82

      Pages: 610-614

    • Related Report
      2010 Final Research Report 2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Differential diagnosis of hyperintense cerebrospinal fluid on fluid-attenuated inversion recovery images of the brain. Part I : pathological conditions.2009

    • Author(s)
      Tha KK, Terae S, Kudo K, Miyasaka K.
    • Journal Title

      Br J Radiol 82

      Pages: 426-434

    • Related Report
      2010 Final Research Report 2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Difference in the Tracer Delay-Induced Effect among Deconvolution Algorithms in CT Perfusion Analysis: Quantitative Evaluation by using Digital Phantoms.2009

    • Author(s)
      Kudo K, Sasaki M, Ogasawara K, Terae S, Ehara S, Shirato H.
    • Journal Title

      Radiology 251

      Pages: 241-249

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Prospective study on the mismatch concept in acute stroke patients within the first 24h after symptom onset -1000Plus study.2009

    • Author(s)
      Hotter B, Pittl S, Ebinger M, Oepen G, Jegzentis K, Kudo K, Rozanski M, Schmidt WU, Brunecker P, Xu C, Martus P, Endres M, Jungehulsing GJ, Villringer A, Fiebach JB.
    • Journal Title

      BMC Neurology 9

      Pages: 60-60

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Glucocorticoids and lithium reciprocally regulate the proliferation of adult dentate gyrus-derived neural precursor cells through GSK-3β and β-catenin/TCF pathway.2009

    • Author(s)
      Boku S
    • Journal Title

      Neuropsychopharmacology 34

      Pages: 805-815

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Difference in the Tracer Delay-Induced Effect among Deconvolution Algorithms in CT Perfusion Analysis : Quantitative Evaluation by using Digital Phantoms2009

    • Author(s)
      Kudo K, Sasaki M, Ogasawara K, Terae S, Ehara S, Shirato H
    • Journal Title

      Radiology 251

      Pages: 241-249

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Detectability of Normal Spinal Veins by Using Susceptibility Weighted Imaging2009

    • Author(s)
      Ishizaka K, Kudo K, Fujima N, Zaitsu Y, Yazu R, Tha KK, Terae S, Sasaki M, Shirato H
    • Journal Title

      J Magn Reson Imaging 31

      Pages: 32-38

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Susceptibility-weighted magnetic resonance imaging detects impaired cerebral hemodynamics in the superior sagittal sinus thrombosis--case report2009

    • Author(s)
      Kawabori M, Kuroda S, Kudo K, Terae S, Kaneda M, Nakayama N, Iwasaki Y
    • Journal Title

      Neurol Med Chir(Tokyo) 49

      Pages: 248-251

    • NAID

      10025947920

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Detection of changes in cerebrospinal fluid space in idiopathic normal pressure hydrocephalus using voxel-based morphometry2009

    • Author(s)
      Yamashita F, Sasaki M, Takahashi S, Matsuda H, Kudo K, Narumi S, Terayama Y, Asada T
    • Journal Title

      Neuroradiology 22(Epub)

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Prospective study on the mismatch concept in acute stroke patients within the first 24h after symptom onset-1000Plus study2009

    • Author(s)
      Hotter B, Pittl S, Ebinger M, Oepen G, Jegzentis K, Kudo K, Rozanski M, Schmidt WU, Brunecker P, Xu C, Martus P, Endres M, Jungehulsing GJ, Villringer A, Fiebach JB
    • Journal Title

      BMC Neurology 9

      Pages: 60-60

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] SSRI・SNRI単剤にて寛解に至らなかった単極性うつ病患者における第二選択治療の有効性に関する調査研究2008

    • Author(s)
      新出泰士, 中島幸治, 北市雄士, 中川伸, 井上猛, 小山司
    • Journal Title

      臨床精神薬理 11

      Pages: 1887-1898

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Depressive patients are more impulsive and inconsistent in intertemporal choice behavior for monetary gain and loss than healthy subjects--an analysis based on Tsallis' statistics.2008

    • Author(s)
      Takahashi T, Oono H, Inoue T, Boku S, Kako Y, Kitaichi Y, Kusumi I, Masui T, Nakagawa S, Suzuki K, Tanaka T, Koyama T, Radford MH
    • Journal Title

      Neuro Endocrinol Lett 29

      Pages: 351-358

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] SSRI・SNRI単剤にて寛解に至らなかった単極性うつ病患者における第二選択治療の有効性に関する調査研究2008

    • Author(s)
      新出泰士, 中島幸治, 北市雄士、中川伸、井上猛、小山司
    • Journal Title

      臨床精神薬理 11

      Pages: 1887-1898

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Depressive patients are more impulsive and inconsistent in intertemporal choice behavior for monetary gain and loss than healthy subjects--an analysis based on Tsallis' statistics2008

    • Author(s)
      Takahashi T, Oono H, Inoue T, Boku Kako Y, Kitaichi Y, Kusumi I, Masui T, Nakagawa S, Suzuki K, Tanaka T, Koyama T, Radford MH
    • Journal Title

      Neuro Endocrinol Lett 29

      Pages: 351-358

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Presentation] Accuracy and reliability of post-proces sing software for ct perfusion : quantitative analysis by digital phantom.2010

    • Author(s)
      Kudo K, Christensen S, Sasaki M, Uwano I, Sasaki T, Ogasawara K, Ostergaard L
    • Organizer
      World Stroke Congress
    • Place of Presentation
      COEX Center, Seoul
    • Year and Date
      2010-10-13
    • Related Report
      2010 Final Research Report
  • [Presentation] ACCURACY AND RELIABILITY OF POST-PROCESSING SOFTWARE FOR CT PERFUSION : QUANTITATIVE ANALYSIS BY DIGITAL PHANTOM2010

    • Author(s)
      Kudo K, Christensen S, Sasaki M, Uwano I, Sasaki T, Ogasawara K, Ostergaard L
    • Organizer
      World Stroke Congress
    • Place of Presentation
      COEX Center(Seoul)
    • Year and Date
      2010-10-13
    • Related Report
      2010 Annual Research Report
  • [Presentation] Neuro Applications of Echelon 1.5T MRI.2010

    • Author(s)
      Kudo K.
    • Organizer
      MRI Seminar in Singapore
    • Place of Presentation
      Singapore
    • Year and Date
      2010-10-09
    • Related Report
      2010 Final Research Report
  • [Presentation] Neuro Applications of Echelon 1.5T MRI2010

    • Author(s)
      Kudo K
    • Organizer
      MRI Seminar in Singapore
    • Place of Presentation
      Singapore
    • Year and Date
      2010-10-09
    • Related Report
      2010 Annual Research Report
  • [Presentation] 中枢神経:CT/MRIのピットフォール脳血管障害2010

    • Author(s)
      工藤與亮
    • Organizer
      日本放射線科専門医会・医会ミッドサマーセミナー
    • Place of Presentation
      神戸ポートピアホテル(神戸)
    • Year and Date
      2010-07-24
    • Related Report
      2010 Annual Research Report
  • [Presentation] Hypothalamic-pituitary-adrenal axis abnormality and hippocampal change in depressed subjects.2010

    • Author(s)
      中川伸
    • Organizer
      第27回CINP
    • Place of Presentation
      HKCEC, Convention Hall BC、香港
    • Year and Date
      2010-06-07
    • Related Report
      2010 Final Research Report
  • [Presentation] Hypothalamic-pituitary-adrenal axis abnormality and hippocampal change in depressed subjects2010

    • Author(s)
      中川伸
    • Organizer
      第27回CINP
    • Place of Presentation
      HKCEC, Convention Hall BC(香港)
    • Year and Date
      2010-06-07
    • Related Report
      2010 Annual Research Report
  • [Presentation] 海馬神経細胞新生と気分障害治療2010

    • Author(s)
      中川伸
    • Organizer
      海馬神経細胞新生と気分障害治療
    • Place of Presentation
      広島国際会議場・アステールプラザ、広島市
    • Year and Date
      2010-05-22
    • Related Report
      2010 Final Research Report
  • [Presentation] 海馬神経細胞新生と気分障害治療2010

    • Author(s)
      中川伸
    • Organizer
      第106回日本精神神経学会
    • Place of Presentation
      広島国際会議場・アステールプラザ(広島市)
    • Year and Date
      2010-05-22
    • Related Report
      2010 Annual Research Report
  • [Presentation] Accuracy and Reliability of Post-Processing Software for DSC MR Perfusion : Quantitative Analysis by Digital Phantom Data.2010

    • Author(s)
      Kudo K, Christensen S, Sasaki M, Straka M, Fujiwara S, Ishizaka K, Zaitsu Y, Fujima N, Terae S, Ogasawara K, Ostergaard L
    • Organizer
      ISMRM (International Socie ty for Magnetic Resonance in Medicine)
    • Place of Presentation
      Stockholmsmassan AB, Stockholm
    • Year and Date
      2010-05-01
    • Related Report
      2010 Final Research Report
  • [Presentation] Improved Quantification of cerebral blood flow change using phase information of SWI, corrected by arterial oxygen saturation.2010

    • Author(s)
      Zaitsu Y, Kudo K, Yazu R, Ishizaka K, Fujima N, Terae S, Sasaki M, Shirato H
    • Organizer
      ISMRM (International Society forMagnetic Resonance in Medicine)
    • Place of Presentation
      Stockholmsmassan AB, Stockholm
    • Year and Date
      2010-05-01
    • Related Report
      2010 Final Research Report
  • [Presentation] Accuracy and Reliability of Post-Processing Software for DSC MR Perfusion : Quantitative Analysis by Digital Phantom Data2010

    • Author(s)
      Kudo K, Christensen S, Sasaki M, Straka M, Fujiwara S, Ishizaka K, Zaitsu Y, Fujima N, Terae S, Ogasawara K, Ostergaard L
    • Organizer
      ISMRM
    • Place of Presentation
      Stockholmsmassan AB (Stockholm)スウェーデン
    • Year and Date
      2010-05-01
    • Related Report
      2010 Annual Research Report
  • [Presentation] Improved Quantification of cerebral blood flow change using phase information of SWI, corrected by arterial oxygen saturation2010

    • Author(s)
      Zaitsu Y, Kudo K, Yazu R, Ishizaka K, Fujima N, Terae S, Sasaki M, Shirato H
    • Organizer
      ISMRM
    • Place of Presentation
      Stockholmsmassan AB (Stockholm)スウェーデン
    • Year and Date
      2010-05-01
    • Related Report
      2010 Annual Research Report
  • [Presentation] 脳卒中の日常臨床における脳循環代謝画像:有用性と限界「CT灌流画像」2010

    • Author(s)
      工藤與亮
    • Organizer
      日本脳卒中学会
    • Place of Presentation
      岩手県民会館(盛岡市)
    • Year and Date
      2010-04-16
    • Related Report
      2010 Annual Research Report
  • [Presentation] Impaired microstructural integrity of frontal white matter in treatment-resistant depression.2010

    • Author(s)
      Tha KK, Terae S, Inoue S, Nakagawa S, Miyamoto T, Fujima N, Zaitsu Y, Koyama T, Shirato H
    • Organizer
      22nd European Congress of Radiology
    • Place of Presentation
      Austria Center Vienna, Bruno Kreisky Platz 1A-1220 Vienna, Austria
    • Year and Date
      2010-03-04
    • Related Report
      2010 Final Research Report
  • [Presentation] Impaired microstructural integrity of frontal white matter in treatment-resistant depression2010

    • Author(s)
      Tha KK, Terae S, Inoue S, Nakagawa S, Miyamoto T, Fujima N, Zaitsu Y, Koyama T, Shirato H
    • Organizer
      22nd European Congress of Radiology
    • Place of Presentation
      Austria Center Vienna, Bruno Kreisky Platz 1A-1220 Vienna, Austria
    • Year and Date
      2010-03-04
    • Related Report
      2009 Annual Research Report
  • [Presentation] デジタルファントムを用いたCT灌流画像解析ソフトの精度検証2010

    • Author(s)
      工藤與亮、Soren Christensen、佐々木真理、笹木工、藤原俊朗、小笠原邦昭、Leif Ostergaard
    • Organizer
      日本神経放射線学会
    • Place of Presentation
      メルパルク横浜、横浜
    • Year and Date
      2010-02-12
    • Related Report
      2009 Annual Research Report
  • [Presentation] うつ病の脳画像所見の臨床的意義2009

    • Author(s)
      井上猛
    • Organizer
      第7回北海道大学脳科学研究教育センターシンポジウム
    • Place of Presentation
      北大学術交流会館、札幌市
    • Year and Date
      2009-12-08
    • Related Report
      2010 Final Research Report 2009 Annual Research Report
  • [Presentation] 神経細胞新生から見た向精神薬の作用機序2009

    • Author(s)
      中川伸
    • Organizer
      第19回日本臨床精神薬理学会・第39回日本神経精神薬理学会合同年会(シンポジウム)
    • Place of Presentation
      国立京都国際会館、京都市
    • Year and Date
      2009-11-13
    • Related Report
      2010 Final Research Report 2009 Annual Research Report
  • [Presentation] Effects of mood stabilizers on adult dentate gyrus-derived neural precursor cell2009

    • Author(s)
      Boku S
    • Organizer
      Society for Neuroscience Meeting
    • Place of Presentation
      Chicago, USA, McCormic Place
    • Year and Date
      2009-10-18
    • Related Report
      2009 Annual Research Report
  • [Presentation] Impaired microstructural white matter integrity in treatment-resistant major depression.2009

    • Author(s)
      Tha KK, Terae S, Inoue S, Nakagawa S, Miyamoto T, Kitaichi Y, Matsui T, Boku S, Fujima N, Zaitsu Y, Koyama T, Shirato H
    • Organizer
      The 1stHokkaido Univ.-Academia Sinica Joint Symposium, The 7th Symposium for Future Drug Discovery and Medical Care
    • Place of Presentation
      北海道大学学術交流会館、札幌市
    • Year and Date
      2009-10-07
    • Related Report
      2010 Final Research Report
  • [Presentation] Impaired microstructural white matter integrity in treatment-resistant major depression2009

    • Author(s)
      Tha KK, Terae S, Inoue S, Nakagawa S, Miyamoto T, Kitaichi Y, Matsui T, Boku S, Fujima N, Zaitsu Y, Koyama T, Shirato H
    • Organizer
      The 1stHokkaido Univ.-Academia Sinica Joint Symposium, The 7th Symposium for Future Drug Discovery and Medical Care
    • Place of Presentation
      北海道大学学術交流会館、札幌
    • Year and Date
      2009-10-07
    • Related Report
      2009 Annual Research Report
  • [Presentation] MR灌流画像解析の標準化に向けたデジタルファントムの作成と応用2009

    • Author(s)
      工藤與亮、Soren Christensen、佐々木真理、藤原俊朗、Leif Ostergaard
    • Organizer
      日本磁気共鳴医学会
    • Place of Presentation
      パンパシフィック横浜ベイホテル東急、横浜市
    • Year and Date
      2009-10-01
    • Related Report
      2010 Final Research Report
  • [Presentation] Impaired frontal white matter integrity in treatment-resistant depression detected by DTI.2009

    • Author(s)
      Tha KK, Terae S, Inoue S, Nakagawa S, Miyamoto T, Matsuyama T, Fujima N, Zaitsu Y, Koyama T, Shirato H
    • Organizer
      第37回日本磁気共鳴医学会大会
    • Place of Presentation
      パンパシフィック横浜ベイホテル東急、横浜市
    • Year and Date
      2009-10-01
    • Related Report
      2010 Final Research Report
  • [Presentation] Impaired frontal white matter integrity in treatment-resistant depression detected by DTI2009

    • Author(s)
      Tha KK, Terae S, Inoue S, Nakagawa S, Miyamoto T, Matsuyama T, Fujima N, Zaitsu Y, Koyama T, Shirato H
    • Organizer
      第37回日本磁気共鳴医学会大会
    • Place of Presentation
      パンパシフィック横浜ベイホテル東急、横浜
    • Year and Date
      2009-10-01
    • Related Report
      2009 Annual Research Report
  • [Presentation] MR灌流画像解析の標準化に向けたデジタルファントムの作成と応用2009

    • Author(s)
      工藤與亮、Soren Christensen、佐々木真理、藤原俊朗、Leif Ostergaard
    • Organizer
      日本磁気共鳴医学会
    • Place of Presentation
      パンパシフィック横浜ベイホテル東急、横浜
    • Year and Date
      2009-10-01
    • Related Report
      2009 Annual Research Report
  • [Presentation] 拡散テンソルによる難治性うつ病における大脳白質障害の検討2009

    • Author(s)
      Tha KK、寺江聡、井上猛、中川伸、宮本環、相馬広幸、藤間憲幸、財津有里、矢部一朗、小山司、白土博樹
    • Organizer
      第120回日本医学放射線学会北日本地方会
    • Place of Presentation
      ホテルニューキャッスル、弘前市
    • Year and Date
      2009-06-20
    • Related Report
      2010 Final Research Report
  • [Presentation] 拡散テンソルによる難治性うつ病における大脳白質障害の検討2009

    • Author(s)
      Tha KK, 寺江聡, 井上猛, 中川伸, 宮本環, 相馬広幸, 藤間憲幸, 財津有里, 矢部一朗, 小山司, 白土博樹
    • Organizer
      第120回日本医学放射線学会北日本地方会
    • Place of Presentation
      ホテルニューキャッスル、弘前
    • Year and Date
      2009-06-20
    • Related Report
      2009 Annual Research Report
  • [Presentation] 認知症とうつ病2009

    • Author(s)
      中川伸
    • Organizer
      北海道高齢者研究会
    • Place of Presentation
      JRタワーホテル、札幌市
    • Year and Date
      2009-06-06
    • Related Report
      2010 Final Research Report 2009 Annual Research Report
  • [Presentation] SWI of the Spinal Veins.2009

    • Author(s)
      Kudo K.
    • Organizer
      ISMRM (International Society for Magnetic Resonance in Medicine)
    • Place of Presentation
      Hawaii conventioncenter, Honolulu, USA
    • Year and Date
      2009-04-18
    • Related Report
      2010 Final Research Report
  • [Presentation] SWI of the Spinal Veins2009

    • Author(s)
      Kudo K
    • Organizer
      ISMRM(International Society for Magnetic Reso nance in Medicine)
    • Place of Presentation
      Honolulu, USA, hawaii conventioncenter
    • Year and Date
      2009-04-18
    • Related Report
      2009 Annual Research Report
  • [Presentation] 難治性うつ病に対するドパミン作動薬の有用性2008

    • Author(s)
      井上猛、小山司
    • Organizer
      第18回日本臨床精神神経薬理学会・第38回日本神経精神薬理学会 合同年会
    • Place of Presentation
      品川プリンスホテル、東京
    • Year and Date
      2008-10-01
    • Related Report
      2010 Final Research Report
  • [Presentation] 難治性うつ病に対するドパミン作動薬の有用性2008

    • Author(s)
      井上猛、小山司
    • Organizer
      第18回日本臨床精神神経薬理学会・第38回日本神経精神薬理学会合同年会
    • Place of Presentation
      東京、品川プリンスホテル
    • Year and Date
      2008-10-01
    • Related Report
      2008 Annual Research Report
  • [Presentation] SWIを用いた定量的脳血流マップの開発2008

    • Author(s)
      工藤與亮
    • Organizer
      日本磁気共鳴医学会
    • Place of Presentation
      旭川市民文化会館、旭川市
    • Year and Date
      2008-09-11
    • Related Report
      2010 Final Research Report
  • [Presentation] SWIを用いた定量的脳血流マップの開発2008

    • Author(s)
      工藤與亮
    • Organizer
      日本磁気共鳴医学会
    • Place of Presentation
      旭川市、旭川市民文化会館
    • Year and Date
      2008-09-11
    • Related Report
      2008 Annual Research Report
  • [Book] 脳科学エッセンシャル-精神疾患の生物学的理解のために(神庭重信、加藤忠史編)(海馬とストレス)2010

    • Author(s)
      中川伸
    • Total Pages
      328
    • Publisher
      中山書店
    • Related Report
      2010 Final Research Report
  • [Book] 脳科学エッセンシャル-精神疾患の生物学的理解のために.2010

    • Author(s)
      中川伸
    • Total Pages
      4
    • Publisher
      中山書店
    • Related Report
      2010 Annual Research Report
  • [Book] Recent developments on depression research.(Yukihiko Shirayama and Shigeyuiki Chaki eds.)(Possible role of adulthippocampal neurogenesis in depression and antidepressant action.)2009

    • Author(s)
      中川伸
    • Total Pages
      256
    • Publisher
      Research Signpost
    • Related Report
      2010 Final Research Report
  • [Book] Recent developments on depression research.2009

    • Author(s)
      Nakagawa S
    • Total Pages
      12
    • Publisher
      Research Signpost
    • Related Report
      2009 Annual Research Report

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Published: 2008-04-01   Modified: 2016-04-21  

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