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Development of X-ray optics for microangiography using synchrotron radiation monochromatic X-rays

Research Project

Project/Area Number 20591468
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Radiation science
Research InstitutionHigh Energy Accelerator Research Organization

Principal Investigator

HYODO Kazuyuki  High Energy Accelerator Research Organization, 物質構造科学研究所, 講師 (60201729)

Co-Investigator(Kenkyū-buntansha) MATSUSHITA Shonosuke  筑波大学, 大学院・人間総合科学研究科, 講師 (70359579)
Project Period (FY) 2008 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2010: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2009: ¥390,000 (Direct Cost: ¥300,000、Indirect Cost: ¥90,000)
Fiscal Year 2008: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Keywords放射光科学 / 放射光単色X線 / 単色X線 / 微小血管造影 / X線分光素子 / 非対称反射 / K吸収端 / 医学物理 / 分光素子 / 心血管系 / 積分反射強度 / 血管造影 / 循環器 / X線光学素子
Research Abstract

Microangiography using synchrotron radiation monochromatic X-rays allows us to evaluate small vessels of less than 100 microns in diameter. Microangiography uses contrast materials, iodine, with a K-edge feature to visualize arterial blood flow as high-contrast images. The purpose of this study was to develop an optimized microangiography system using a new two-dimensional X-ray detector and X-ray optics. Many applications are expected by the developed system.

Report

(4 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (25 results)

All 2011 2010 2009 2008

All Journal Article (8 results) (of which Peer Reviewed: 4 results) Presentation (17 results)

  • [Journal Article] Identification of microvascular coronary spasm using synchrotron radiation microangiography.2010

    • Author(s)
      S.Matsushita, K.Hyodo, 他
    • Journal Title

      Photon Factory Activity Report 2009 (Part B)

      Pages: 257-257

    • Related Report
      2010 Final Research Report
  • [Journal Article] Evaluation of revascularization by arteriole/capillary ratio using synchrotron radiation coronary angiography.2010

    • Author(s)
      T.Imazuru, S.Matsushita, K.Hyodo, 他
    • Journal Title

      Photon Factory Activity Report 2009 (Part B)

      Pages: 258-258

    • Related Report
      2010 Final Research Report
  • [Journal Article] Unexpected vasodilation due to cold exposure assessed by synchrotron radiation micro-angiography.2010

    • Author(s)
      F.Sato, K.Hyodo, S.Matsushita, 他
    • Journal Title

      Photon Factory Activity Report 2009 (Part B)

      Pages: 259-259

    • Related Report
      2010 Final Research Report
  • [Journal Article] Various aspects of cigarette smoke induced vasoconstriction of peripheral arteries assessed by synchrotron radiation micro-angiography.2010

    • Author(s)
      S.Akishima, S.Matsushita, K.Hyodo, 他
    • Journal Title

      Photon Factory Activity Report 2009 (Part B)

      Pages: 260-260

    • Related Report
      2010 Final Research Report
  • [Journal Article] Giant coronary artery aneurysm with pulmonary artery fistula in a patient on chronic hemodialysis.2010

    • Author(s)
      C.Tokunaga, 他, S.Matsushita
    • Journal Title

      Ann Thorac Surg 89

      Pages: 963-965

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Development of FOP-HARP imaging device.2010

    • Author(s)
      K.Miyakawa, 他, S.Matsushita, K.Hyodo
    • Journal Title

      Proc.of SPIE-IS&T Electronic Imaging, SPIE Vol.7536

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Development of FOP-HARP imaging device2010

    • Author(s)
      K.Miyakawa, et al.
    • Journal Title

      Proceedings of SPIE 7536

      Pages: 7536041-7536048

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Erythropoietin enhances arterioles more significantly than it does capillaries in an infarct rat heart model.2009

    • Author(s)
      T.Imazuru, S.Matsushita, K.Hyodo, 他
    • Journal Title

      Int.Heart J 50(6)

      Pages: 801-810

    • NAID

      130000120862

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Presentation] X-ray imaging stations for medical applications at Photon Factory2011

    • Author(s)
      兵藤一行, 他
    • Organizer
      The 5^<th> Asian Meeting on Synchrotron Radiation Biomedical Imaging
    • Place of Presentation
      Andon, Korea(招待)
    • Year and Date
      2011-10-30
    • Related Report
      2010 Final Research Report
  • [Presentation] X-ray imaging stations for medical applications at Photon Factory2011

    • Author(s)
      K.Hyodo
    • Organizer
      The 5^<th> Asian Meeting on Synchrotron Radiation Biomedical Imaging
    • Place of Presentation
      Andong General Hospital (Andon, Korea)
    • Year and Date
      2011-10-30
    • Related Report
      2010 Annual Research Report
  • [Presentation] レーザー逆コンプトン微小X線光源によるX線イメージングの応用研究2011

    • Author(s)
      兵藤一行
    • Organizer
      第24回日本放射光学会
    • Place of Presentation
      茨城県つくば市
    • Year and Date
      2011-01-08
    • Related Report
      2010 Final Research Report
  • [Presentation] レーザー逆コンプトン微小X線光源によるX線イメージングの応用研究2011

    • Author(s)
      兵藤一行
    • Organizer
      第24回日本放射光学会
    • Place of Presentation
      つくば国際会議場(茨城県)
    • Year and Date
      2011-01-08
    • Related Report
      2010 Annual Research Report
  • [Presentation] Cardiac sympathetic activity assessed by heart rate variability indicates myocardial ischemia on cold exposure in diabetes2010

    • Author(s)
      K.Sasaki, S.Matsushita, Y.Sakakibara
    • Organizer
      The 45th Annual Meeting of Experimental Biology
    • Place of Presentation
      Anaheim, U.S.A.
    • Year and Date
      2010-04-27
    • Related Report
      2010 Final Research Report
  • [Presentation] 放射光微小血管撮影を用いた寒冷負荷血管反応の研究2010

    • Author(s)
      佐藤藤夫, 松下昌之助, 兵藤一行, 他
    • Organizer
      第27回PFシンポジウム
    • Place of Presentation
      茨城県つくば市
    • Year and Date
      2010-03-09
    • Related Report
      2010 Final Research Report
  • [Presentation] X線イメージング用ビームラインの再編2010

    • Author(s)
      兵藤一行, 他
    • Organizer
      第27回PFシンポジウム
    • Place of Presentation
      茨城県つくば市
    • Year and Date
      2010-03-09
    • Related Report
      2010 Final Research Report 2009 Annual Research Report
  • [Presentation] New experimental stations for X-ray imaging at the photon factory2010

    • Author(s)
      兵藤一行, 他
    • Organizer
      International Workshop on Medical Application of Synchrotron Radiation
    • Place of Presentation
      Melbourne, Australia
    • Year and Date
      2010-02-15
    • Related Report
      2010 Final Research Report
  • [Presentation] New Experimental Stations for X-ray Imaging at Photon Factory2010

    • Author(s)
      K.Hyodo, et al.
    • Organizer
      International Workshop on Medical Application of Synchrotron Radiation
    • Place of Presentation
      オーストラリアメルボルン国際会議場
    • Year and Date
      2010-02-15
    • Related Report
      2009 Annual Research Report
  • [Presentation] Development of FOP-HARP imaging device.2010

    • Author(s)
      K.Miyakawa, 他, S.Matsushita, K.Hyodo
    • Organizer
      SPIE2010
    • Place of Presentation
      San Jose, USA
    • Year and Date
      2010-01-16
    • Related Report
      2010 Final Research Report
  • [Presentation] 放射光と高感度受像管を用いた新しい血管造影検査システムによる造影剤使用量低減の試み2009

    • Author(s)
      小西泰介,松下昌之助,兵藤一行, 他
    • Organizer
      第50回日本脈管学会総会
    • Place of Presentation
      東京
    • Year and Date
      2009-10-30
    • Related Report
      2010 Final Research Report
  • [Presentation] Erythropoietin enhances arteriogenesis more significantly than it does angiogenesis in the infarcted rat heart2009

    • Author(s)
      今水流智浩, 松下昌之助, 兵藤一行, 他
    • Organizer
      第50回日本脈管学会総会
    • Place of Presentation
      東京
    • Year and Date
      2009-10-30
    • Related Report
      2010 Final Research Report
  • [Presentation] 腎機能障害に対応し、造影剤の軽減をめざした高感度血管造影法の開発2009

    • Author(s)
      松下昌之助,小西泰介,兵藤一行, 他
    • Organizer
      第26回PFシンポジウム
    • Place of Presentation
      茨城県つくば市
    • Year and Date
      2009-03-25
    • Related Report
      2010 Final Research Report
  • [Presentation] PF-AR NE7の建設とBL14C改造計画について2009

    • Author(s)
      兵藤一行, 他
    • Organizer
      第26回PFシンポジウム
    • Place of Presentation
      茨城県つくば市
    • Year and Date
      2009-03-25
    • Related Report
      2010 Final Research Report
  • [Presentation] PF-AR NE7の建設とBL14C改造計画について2009

    • Author(s)
      兵藤一行, 他
    • Organizer
      第26回PFシンポジウム
    • Place of Presentation
      茨城県 つくば市
    • Year and Date
      2009-03-25
    • Related Report
      2008 Annual Research Report
  • [Presentation] Medical imaging stations at the photon factory2008

    • Author(s)
      K.Hyodo, M.Ando
    • Organizer
      The 3^<rd> Asian Meeting on Synchrotron Radiation Biomedical Imaging
    • Place of Presentation
      雲南省,中国(招待)
    • Year and Date
      2008-10-31
    • Related Report
      2010 Final Research Report
  • [Presentation] Medical Imaging Stations at the Photon Factory2008

    • Author(s)
      K. Hyodo, M. Ando
    • Organizer
      The 3^<rd> Asian Meeting on Synchrotron Radiation Biomedical Imaging
    • Place of Presentation
      中国 雲南省
    • Year and Date
      2008-10-31
    • Related Report
      2008 Annual Research Report

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Published: 2008-04-01   Modified: 2016-04-21  

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